Navigation Links
Isis Pharmaceuticals And AstraZeneca Form Strategic Alliance On RNA Therapeutics For Cancer
Date:12/11/2012

s reflect a common goal of bringing new medicines to cancer patients."

"We are excited to collaborate with AstraZeneca, a global leader in oncology, to apply our technology and drug discovery expertise to developing novel anti-cancer agents. We will benefit from AstraZeneca's extensive oncology expertise in the use of novel pre-clinical animal models to validate targets and develop predictive assays to identify which patients would benefit the most from these new targets," said B. Lynne Parshall, chief operating officer and chief financial officer at Isis.

"ISIS-STAT3Rx is our first cancer drug to incorporate our new technology and we are encouraged by the early clinical data we have observed," said Brett Monia, Ph.D., senior vice president, antisense drug discovery at Isis. "While STAT3 is implicated in a number of different cancers, the focus in our ongoing clinical study is to evaluate the effectiveness of our drug in hematologic malignancies, such as lymphoma. We have worked closely with AstraZeneca to design a rapid path to the market for ISIS-STAT3Rx in these patient populations. While working toward this goal, AstraZeneca's resources, expertise and development capabilities also provide us the opportunity to evaluate ISIS-STAT3Rx as a broad-based anti-tumor agent."

Under the terms of the agreement, Isis will receive from AstraZeneca $31 million in upfront and near term payments, comprising a $25 million payment on signing followed by a $6 million payment in the second quarter of 2013 assuming the research program is continuing. In exchange, Isis has granted AstraZeneca an exclusive license to develop and commercialise ISIS-STAT3Rx and a pre-clinical program as well as an option to license products developed under a separate research program. Once licensed, AstraZeneca will be responsible for all further development and commercialization. AstraZeneca will be responsible fo
'/>"/>

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Biogen Idec and Isis Pharmaceuticals Announce Collaboration For Antisense Programs To Treat Neurological Disorders
2. Isis Pharmaceuticals Reports Positive Phase 1 Data On Three Drugs In Development To Treat Metabolic Disorders
3. AcelRx Pharmaceuticals Announces Pricing of Public Offering of Common Stock
4. Arena Pharmaceuticals to Present at the Oppenheimer 23rd Annual Healthcare Conference
5. Valeant Pharmaceuticals And Galderma Agree On Revised Agreement Terms
6. Optimer Pharmaceuticals to Present at 23rd Annual Oppenheimer Healthcare Conference
7. AcelRx Pharmaceuticals Announces Proposed Public Offering Of Common Stock
8. Additional Clinical Data from Two Trials on Actinium Pharmaceuticals Iomab-B to be Presented at American Society of Hematology (ASH) Annual Meeting
9. Salix Pharmaceuticals Donates $500,000 To ASGEs IT&T Capital Campaign To Build A New State-of-the-Art GI Training Center
10. Questcor Pharmaceuticals Accelerates Cash Dividend; Payment Date Set for December 21, 2012
11. Double-digit Growth Rate of the Pharmaceuticals Industry in Asia Pacific Boosts the API Market, Finds Frost & Sullivan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/16/2015)... China , April 16, 2015 ... leading developer, manufacturer, and marketer of medical devices ... the Securities and Exchange Commission an Annual Report on ... the year ended December 31, 2014. An electronic version ... available on Mindray,s investor relations website at  http://ir.mindray.com ...
(Date:4/16/2015)... Mass. , April 16, 2015  Hologic, ... important cervical cancer screening study i published ... a peer-reviewed journal of the American Cancer Society. ... Diagnostics and the University of Pittsburgh Medical Center, supports current ... which recommend that women 30-65 years of age ...
(Date:4/16/2015)... , April 16, 2015  Amgen (NASDAQ: AMGN ... quarter financial results on Tuesday, April 21, 2015, after ... will be followed by a conference call with the ... call from Amgen will be Robert A. Bradway ... of Amgen,s senior management team. Live audio ...
Breaking Medicine Technology:Mindray Files Annual Report on Form 20-F with the U.S. Securities and Exchange Commission 2Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 2Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 3Hologic Comments on Important Cervical Cancer Screening Study Published in the American Cancer Society Journal, Cancer Cytopathology 4Amgen Announces Webcast Of 2015 First Quarter Financial Results 2
(Date:4/18/2015)... 2015 Lower-auto-insurance.com has released a new ... auto insurance quotes . , Drivers can find ... quotes. A professional insurance brokerage website can help drivers ... a simple, convenient way. The whole process is designed ... , Comparing online car insurance quotes is advantageous because ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 On April 14th, ... Threat Report , which they say, “exposes a tactical shift ... new malware variants were introduced in 2014 - almost a ... Zero Day threats to be identified and patched by prominent ... abundantly clear that doing business in a digital world can ...
(Date:4/17/2015)... Heritage Woods of McLeansboro, a Gardant affordable assisted ... on April 20 with a day full of activities ... soul. , The community, which is located at 605 ... all incomes, including those on Medicaid, who need some ... is observed every April and highlights the communities within ...
(Date:4/17/2015)... 17, 2015 Alcohol and Violence , ... notes that drinking and driving has been the focus ... same time, the link between alcohol and crime received ... and violence and sexual assault, and their relationship to ... NCADD, 5.3 million adults in America were drinking alcohol ...
(Date:4/17/2015)... Jose, CA (PRWEB) April 17, 2015 ... life insurance protection without modifications can now use the ... now general life insurance policy rates that are featured ... , The standard plans that are offered are mixed ... adults aged 18 to 79. There are now term, ...
Breaking Medicine News(10 mins):Health News:Auto Insurance Quotes Can Provide Accurate Results! 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3Health News:General Life Insurance Policy Rates Added to Quotation System at Insurance Website Online 2
... the risk of developing lung cancer although the effect is ... over 200 women under the age of 80 with primary ... Teeside, northeast England, reported Newswise wire. ,Rates of ... of England, where heavy industries expanded rapidly throughout the 19th ...
... of Bihar's 32 districts are infected with kala azar, ... government apathy make the disease endemic to the region. ... in collaboration with the World Health Organisation (WHO) and ... plains of the state are infected with kala azar. ...
... a specially equipped aircraft early Wednesday from Merignac Airport in ... in weightless conditions, the Bordeaux University Hospital Centre (CHU) said. ... surgical module, which could serve as a prototype for equipment ... of outer space. ,The surgery will be to ...
... likely to grow into overweight children than formula-fed babies, says ... teenagers in the US are overweight, according to government statistics. ... two to 19 years, reported an online edition of health ... in the US studied 15,253 children between the ages of ...
... play host to a new entrant - oseltamivir or popularly ... the Director of patent policy in Canada, Douglas Clark. This ... of generic drug manufacturers, who can now avail the license ... ,Biolyse Pharma Corp., a leading pharmaceutical company, ...
... decrease the need of insulin injections for people with type ... Shapiro, M.D., Ph.D., from the University of Alberta in Edmonton, ... Journal of Medicine. ,In this study, processed islet ... by this disease for around 27 years. There is a ...
Cached Medicine News:Health News:Bihar Districts Affected by Black Fever 2Health News:Bihar Districts Affected by Black Fever 3
... Designed with 96-well plates in mind, ... for molecular biology applications: PCR* sequencing, ... plates, etc. Used with Diamond Tips ... this product will maximize performance and ...
... The Finnpipette Digital Multichannel, with ... lighter work of routine laboratory ... these advanced features: Soft-touch tip ... volume pipetting (0.5-10ul models), Entire ...
... multichannel pipettes speed up ... into microplates, with super ... volumes. The improved ergonomic ... multichannels, combined with super ...
... 96-well plates in mind, Pipetman Ultra ... biology applications: PCR* sequencing, immunology assays, ... Used with Diamond Tips from Gilson's ... will maximize performance and assure productivity.,* ...
Medicine Products: