Navigation Links
Ironwood and Forest Present Additional Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation
Date:5/31/2009

nal linaclotide presentations being made this week at DDW will be:

  • Abstract 236: Global Endpoints in IBS Clinical Trials: Results from a Phase 2b Study of Linaclotide, an oral presentation by Jeffrey Johnston, M.D., F.A.C.P., F.A.C.G. on Sunday, May 31 at 2:30 p.m. CT; McCormick Place, Room E352
  • Abstract 418: Effect of Linaclotide on Quality of Life in Adults with Chronic Constipation: Results from a Phase 2b Study, an oral presentation by Bernard J. Lavins, M.D. on Monday, June 1 at 2:15 p.m. CT; McCormick Place, Room S406A
  • Abstract 1273: Time to Onset of Linaclotide Effect on the Bowel Habits in Patients with Chronic Constipation: Results from a Phase 2b Study, a poster presentation by Jeffrey Johnston, M.D., F.A.C.P., F.A.C.G. on Tuesday, June 2 from 8:00 a.m. to 5:00 p.m. CT; McCormick Place, South Hall

Ironwood and Forest presented the initial analyses from both the IBS-C and CC studies last year.

IBS-C Phase 2b Study Design

This North American-based, randomized, multi-center, double-blind, placebo-controlled, dose-range-finding, parallel-group Phase 2b study was designed to assess the safety, efficacy, and dose response of linaclotide in patients with IBS-C. The primary efficacy endpoint was change from baseline in complete spontaneous bowel movement (CSBM) frequency. The study evaluated the effects of 75, 150, 300, or 600 ug linaclotide or placebo administered orally once daily to adults meeting modified Rome II criteria for IBS-C. Participants underwent a two-week pretreatment (baseline) period before undergoing the 12-week treatment period, followed by a two-week post-treatment period. Daily assessments of bowel habits and symptom severity, and weekly global assessments were performed using an interactive voice response system. During the baseline period patients had to demonstrate <3
'/>"/>

SOURCE Forest Laboratories, Inc.; Ironwood Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Ironwood Announces Linaclotide European Licensing Agreement with Almirall
2. Ironwood and Forest Present Positive Phase 2b Study Results for Linaclotide in Patients With Irritable Bowel Syndrome With Constipation
3. Ironwood and Collaborators Present Preclinical Data Demonstrating That Cyclic GMP Alleviates Intestinal Pain
4. Ironwood Raises $50 Million to Advance Linaclotide Through Phase 3
5. Ironwood and Forest to Present Positive Data From Linaclotide Phase 2b IBS-C Study at ACG Annual Scientific Conference
6. Ironwood Pharmaceuticals and Forest Laboratories Announce Presentation of Linaclotide Phase 2b Chronic Constipation Study Results
7. Forest Laboratories, Inc. and Laboratorios Almirall, S.A. Provide an Update on the Aclidinium Bromide Clinical Development Program
8. Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study of Milnacipran for the Management of Fibromyalgia
9. Forest Laboratories, Inc. and Gedeon Richter Plc Announce Positive Phase II Results with the Investigational Antipsychotic Cariprazine in Patients with Acute Mania Associated with Bipolar I Disorder
10. Forest Laboratories Announces Positive Results from Phase III Clinical Studies of Ceftaroline for the Treatment of Complicated Skin and Skin Structure Infections
11. Forest and Almirall Announce Positive Results of Clinical Studies for Aclidinium Bromide, a Novel, Long-Acting Anticholinergic for the Treatment for COPD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/29/2015)... June 29, 2015 Axxess , an ... the only software vendor accredited by the American Nursing ... helping home health agencies select the right revenue cycle ... and grow their business. Research by American ... providers should expect a decrease in productivity of 54.4 ...
(Date:6/29/2015)... , June 29, 2015  Arbor Solution ... workstation lineup. The high-powered, multi-functional M2150 ... Intel® Haswell Core i5-4402E 1.6 GHz ... significant data processing and computing performance. Integrated Intel® ... the unit well suited for graphics-intense applications in ...
(Date:6/29/2015)... SAN FRANCISCO , June 29, 2015 ... 47.54 billion by 2020, according to a new study by Grand ... II diabetes and the presence of high unmet needs in emerging ... China are expected to be two of the most ... lifestyle induced diseases such as obesity and growing global geriatric population ...
Breaking Medicine Technology:Axxess Releases eGuide for Home Health Agencies, Revenue Cycle Management: What You Must Do Now - to Succeed! 2Arbor Solution Introduces Multi-Function Medical Workstation with Large 21.5" True Flat Touch Screen 2Arbor Solution Introduces Multi-Function Medical Workstation with Large 21.5" True Flat Touch Screen 3Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 2Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 3Insulin Market To Reach $47.54 Billion By 2020: Grand View Research, Inc. 4
... Aung FootHealth Clinics &,Advanced Wound Care Center today ... foot ulcers to participate in the MATRIX clinical,trial. ... Excellarate(TM) (GAM501),(Ad5PDGF-B/bovine Type I collagen gel) for the ... ulcers. Excellarate is,an investigational product designed to stimulate ...
... participate in controversial debate over effects of ... Simvastatin vs. Ezetimibe/Simvastatin, ... medical professionals, will air on XM Satellite Radio Channel,157 ... a candid medical,discussion on the much talked-about ENHANCE (Effect ...
Cached Medicine Technology:Aung FootHealth Clinics & Advanced Wound Care Center Enrolling Patients With Chronic Diabetic Foot Ulcers for Matrix Clinical Trial 2ReachMD Broadcasts First-of-its-Kind Physician Peer-Peer Discussion on ENHANCE Trial 2
(Date:6/30/2015)... ... June 30, 2015 , ... Healthy ... enhance successful student outcomes. According to Dr. Theo Wubbels (Professor of Education, ... must be able to show “all kinds of behavior when the situation asks ...
(Date:6/30/2015)... ... 2015 , ... This Fourth of July, Peacock Alley celebrates the ... work, tenacity, perseverance, commitment to quality, honesty and love of friends and family. These ... Gabler's simple love of quilts, Peacock Alley was fully realized and grown while raising ...
(Date:6/29/2015)... ... June 30, 2015 , ... The National Association ... inductee into its VIP Woman of the Year Circle. She is recognized with ... organization exclusively for professional women, boasting more than 700,000 members and over 200 ...
(Date:6/29/2015)... ... June 30, 2015 , ... The United States ... Team (KORT) as it becomes the Official Physical and Occupational Therapists of the U.S. ... Rolex Kentucky Three-Day Event presented by Land Rover. , “The USEF is pleased ...
(Date:6/29/2015)... ... 2015 , ... Career Step, an online institution offering career-focused ... administrators with hospitals, healthcare providers, and insurance companies. The new website is intended ... comprehensive research and implementation of web design and marketing best practices. , ...
Breaking Medicine News(10 mins):Health News:Lessons On Leadership - Top 12 Global Teacher Bloggers Reveal the Best Strategies for Building Positive Leadership in Global Classrooms 2Health News:Luxury Linen Purveyor Peacock Alley Celebrates the Fourth of July 2Health News:National Association of Professional Women Inducts Melanie Richards, DMD, of Powdersville Pediatric Dentistry, Into its VIP Woman of the Year Circle 2Health News:KORT Physical Therapy Announces Partnership with The United States Equestrian Federation 2Health News:Career Step Launches New Website to Better Meet Needs of Partners, Clients and Others Searching for Corporate Training Solutions 2
... computed tomography (CT), magnetic resonance imaging and molecular imaging ... multi-modal contrast agent – Researchers // at the University ... these new agents may, in turn, significantly improve the ... a professor in the department of speech and hearing ...
... In the race for supremacy in the Indian biotech ... spot during the fiscal (2005-06) // by contributing ... (Rs.65 billion) as against 37 percent by the southern ... performance, Karnataka Biotech Vision group chairperson Kiran Mazumdar-Shaw told ...
... has been develooped to assess the risk of heart disease ... wrongly assessed. // ,ETHRISK is for everyday use ... has been developed by researchers at the University of Bristol ... British black and minority ethnic groups. ,Ethnic groups within Britain ...
... African union and aid organisations said on Wednesday, that, Africa ... years. // This is about three times as much as the ... pledge, in Beijing, made at a donors conference did not expect ... been reported in eight African countries since February, and this ...
... revealed that while the chances of surviving a heart attack ... unchanged. // ,The Canadian Institute for Health Information ... rate for people suffering a new heart attack fell to ... 1999-2000 whereas in the case of strokes, 18.8 per cent ...
... According to the recent report from the health authorities of central ... disease//. Statistics show that the disease is prevalent in the month ... ,The scenario was worse in 2002 were human deaths crossed 66. ... by the health authorities the number of deaths reduced to 12 ...
Cached Medicine News:Health News:New Multi-Modal Contrast Agents, A Boon For Medical Imaging 2Health News:New Multi-Modal Contrast Agents, A Boon For Medical Imaging 3Health News:New Multi-Modal Contrast Agents, A Boon For Medical Imaging 4Health News:Western Region Tops in Indian Biotech Growth 2Health News:New Web- Based Calculator to Assess Heart Disease Risk 2Health News:Survival Rates of Heart Attack Improving 2
... curtains or parting strip shields ... frame to form a free-standing, ... cleanliness to Class 10/ISO 3. ... lights, and ionizers are configured ...
Inquire...
Inquire...
Inquire...
Medicine Products: