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Ipsogen Launches a New Test to Determine Tumor HER2 Status and Guide Herceptin(R) Prescription in Breast Cancer
Date:11/24/2008

MARSEILLE, France, November 24 /PRNewswire-FirstCall/ -- IPSOGEN SA (Marseille, France and New Haven, CT, USA), a cancer profiler that markets molecular diagnostic assays for leukemia and breast cancer announced today the European launch of MapQuant Dx(TM) HER2 test. Developped on the MapQuant Dx(TM) microarray diagnostic platform, MapQuant Dx(TM) HER2 accurately measures a set of HER2-amplified genes that correlate with HER2 protein expression. This new HER2 test provides reliable, intelligible and decisive information for pathologists, oncologists and patients.

"MapQuant(TM) Dx HER2 is the second test to be developped on our MapQuant Dx(TM) platform, after the Genomic Grade launched by Ipsogen earlier this year. Thanks to our experience in molecular diagnostics and to multiple research collaborations, we will keep delivering innovative tests at an accelarated pace." says Dr. Jean-Marc Le Doussal, Director of the Breast Cancer Program at Ipsogen.

Commenting on its experience with Ipsogen, Pr. Francois Bertucci, Medical Oncologist at Institut Paoli Calmettes Cancer Center in Marseille adds: "I was very pleased to collaborate with Ipsogen in rapidly and efficiently moving from our research findings to a market-ready diagnostic test. As a translational researcher, I believe that MapQuant Dx(TM) is a comprehensive "plug & play" solution, making research rapidly available to patients".

About MapQuant Dx(TM) HER2

Clinical Rationale

The amplification of the HER2-region of chromosome 17 results in the constitutive overexpression of the HER2 oncogene protein and fuels uncontroled tumor growth in approximately 15 to 30% of breast tumors. HER2 is considered today as a predictive marker for clinical benefit from trastuzumab, or Herceptin(R), a monoclonal antibody directed against the HER2 protein, in both primary and metastatic tumors. However current testing methods are inaccur
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SOURCE Ipsogen SA
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