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Ion Torrent Cancer Panel Finds Mutations in One Day
Date:10/12/2011

o it successfully. The technology is ideal for FFPE or biopsy research samples because it requires only 10 ng of DNA, yet it's sensitive enough to detect variation present in complex research samples at only a 5 percent frequency.

Scalability: Ion AmpliSeq™ technology is highly scalable, accommodating hundreds of genes or DNA regions up to 500 kb in size. It also accommodates a range of budgets. For small projects, researchers can use the Ion 314™ chip for just $99. For larger projects or for barcoding samples, researchers can use the 100 Mb Ion 316™ chip or the 1 Gb Ion 318™ chip, available by the end of 2011. Ion AmpliSeq™ technology is compatible with barcodes and fully configurable in 96 or 384 well plate formats - delivering additional scalability. More information regarding AmpliSeq™ Custom Kits may be obtained at:  www.iontorrent.com/community .

Early access customers have reported excellent results with the Ion AmpliSeq™ Cancer Panel:

"While we have only been using Ion AmpliSeq™ Cancer Panels for a short time, we are very pleased with the results," said Dr. Christopher Corless, Medical Director of the Knight Diagnostic Laboratories at Oregon Health and Science University. "We've been able to obtain perfect correlation, in that every mutation we knew about going into the study emerged on the other end of the Ion PGM™ sequencer as an exact match. This technology has enormous potential in clinical research because it's so simple and will enable us to rapidly get more information to our hematologists and oncologists for less money." View a video interview with Dr. Corless.

"The product is remarkably easy to use with very little 'hands on' time," said Marjolijn Ligtenberg, the head of the Laboratory of Tumor Genetics at the Radboud Un
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SOURCE Life Technologies Corporation
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