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Ion Torrent Cancer Panel Finds Mutations in One Day
Date:10/12/2011

CARLSBAD, Calif., Oct. 12, 2011 /PRNewswire/ -- Life Technologies Corporation (NASDAQ: LIFE) today announced the launch of the Ion AmpliSeq™ Cancer Panel, enabling scientists to sequence dozens of genes in cancer research samples using a simple workflow. Mutations are confirmed within just one day, starting with a single-tube reaction and 10 ng of DNA extracted from fixed, frozen or fresh tissue. Novel Ion AmpliSeq™ kits prepare targeted regions for sequencing in 3.5 hours of total time, with under 10 minutes of hands-on time, just like standard PCR. The method is scalable to hundreds of genes. Current methods require weeks of work to generate hundreds of gene regions via PCR or hybridization-based capture.

This dramatic improvement in time-to-result will accelerate cancer research, enabling even small labs to run thousands of research samples a year.  The Ion AmpliSeq™ Cancer Panel sequences 46 cancer-related genes for over 700 known cancer mutations.  The panel was chosen in collaboration with leading oncologists and cancer researchers. View a video with an Ion AmpliSeq™ user.

Speed: The Ion AmpliSeq™ Cancer Panel enables researchers to sequence 190 amplicons in one day starting with a 3.5 hour amplification reaction, then Ion OneTouch™ template preparation, and finally a sequencing run that takes just 90 minutes.

Simplicity: The Ion AmpliSeq™ Cancer Panel is the simplest solution because researchers just add DNA to a single tube containing all primers. It's as easy to perform as endpoint PCR, so any trained laboratory technician can d
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SOURCE Life Technologies Corporation
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