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Ion Mobility Diagnostic Test from Quest Diagnostics is First to Provide Direct Physical Measurement of Lipoprotein Particles, Cardiovascular Disease Indicators, Study Finds
Date:6/3/2008

MADISON, N.J., June 3 /PRNewswire-FirstCall/ -- Quest Diagnostics Incorporated (NYSE: DGX) today announced results of a study that demonstrates that a novel diagnostic testing technique it has developed is the first to provide direct, accurate and reproducible physical measurement of both the size and concentration of a broad range of lipoproteins in blood plasma. Results of the study were published in the May 29, 2008, online edition of Clinical Chemistry.

"Our data suggest that this novel ion mobility-based method offers advantages over other procedures for lipoprotein particle analysis because it both measures particle size accurately on the basis of physical principles as well as directly counts the particles present at each size independently of particle composition. We believe this approach provides the only direct physical measurement of lipoprotein particle size and concentration for each lipoprotein subclass, from small HDL to large VLDL," said Richard E. Reitz, MD, co-lead investigator and acting vice president, Science and Innovation, and medical director, Quest Diagnostics Nichols Institute. "We look forward to learning the results of additional research to identify the technique's clinical utility for risk assessment and treatment in patients with cardiovascular disease and related conditions."

Lipoprotein particles are fatty substances carried through the blood stream that affect cardiovascular health. High-density lipoproteins (HDL), referred to as "good" cholesterol, promote healthy cardiovascular function, but LDL and very-low density lipoproteins (VLDL), or "bad" cholesterol, may deposit on the walls of arteries, promoting atherosclerosis and other cardiovascular diseases. Because particles of LDL, intermedi
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SOURCE Quest Diagnostics Incorporated
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