Navigation Links
Iomai Trial Shows 100 Percent Immune Response in Elderly Subjects Vaccinated With Novel Travelers' Diarrhea Patch Vaccine
Date:8/19/2007

st week, provide additional evidence of the significant potential for Iomai's transcutaneous immunization (TCI) approach."

Iomai last week announced that a Phase 2 field trial of the vaccine found that healthy adults who traveled to Guatemala and Mexico and were vaccinated with the Iomai patch were 75 percent less likely to suffer moderate or severe travelers' diarrhea. With the high seroconversion rates in the elderly, the interim results from this new study suggest that the protective effect of Iomai's travelers' diarrhea vaccine may apply to all adults, not just young adults. Iomai will look to confirm this in its Phase 3 trials for its travelers' diarrhea vaccine, which the company intends to launch in 2008.

The study was designed to evaluate the safety of the travelers' diarrhea vaccine patch in the elderly and it met this primary endpoint. The secondary objective included evaluation of immunogenicity of the vaccine in the elderly compared with young adults. Iomai plans to submit the study data from the trial for publication as soon as possible.

ABOUT TRAVELERS' DIARRHEA

This year, approximately 55 million international travelers will visit countries where bacteria that cause travelers' diarrhea are endemic, particularly Africa, Asia and Latin America, and about 20 million of those travelers will develop travelers' diarrhea.

ETEC, the most common cause of travelers' diarrhea, represents just under half of all cases of travelers' diarrhea for international travelers to areas where ETEC is common. A recently completed market study suggested that there is a large market for an effective ETEC vaccine, potentially exceeding $500 million annually. If approved, the Iomai vaccine would be the first vaccine for travelers' diarrhea available in the United States.

ETEC's impact goes beyond travelers. The World Health Organization estimates that children in the developing world suffer 210 million episodes of diarrhea caused by ETEC annua
'/>"/>

SOURCE Iomai Corporation

Copyright©2007 PR Newswire.

Page: 1 2 3 4

Related medicine technology :

1. Iomai to Announce Results From Phase 1 Influenza Trial and Host Webcast Tomorrow
2. Iomai Dose-Ranging Trial Demonstrates Needle-Free Patch Vaccine for Travelers Diarrhea Stimulates Immune Response Even at Low Doses
3. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
4. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
5. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
6. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
7. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
8. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
9. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
10. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
11. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Tegra Medical is very pleased to announce the appointment ... Chief Executive Officer.  Mark was promoted from his current role ... company,s four facilities in Massachusetts , ... Tegra Medical in 2012 with 20+ years of broad-based operations, ...
(Date:1/15/2014)... Jan. 15, 2014 Reportlinker.com announces that ... in its catalogue: ... Analysis http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are gaining ...
(Date:1/15/2014)... Mass. , Jan. 15, 2014  Zafgen, Inc., ... unmet needs of severely obese patients, today announced ... beloranib, a selective inhibitor of methionine aminopeptidase 2 ... severe form of genetic obesity.  These results showed ...
Breaking Medicine Technology:Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4
(Date:4/18/2014)... worst memories? How did it make you feel? According ... personal experience, such as how sad you were or ... especially when you can,t stop thinking about it. ... the context of the memories, rather than how you ... alleviate the negative effects of these memories, a new ...
(Date:4/18/2014)... in French . ... and regenerative medicine. A team led by Ludwik Leibler ... Tech) and Didier Letourneur from the Laboratoire Recherche Vasculaire ... demonstrated that the principle of adhesion by aqueous solutions ... soft-tissue organs and tissues. This easy-to-use gluing method has ...
(Date:4/17/2014)... variant specifically associated with the risk of a ... cent of all breast cancer cases. , The ... called invasive lobular carcinoma, gives researchers important clues ... of breast cancer, which can be missed through ... the journal PloS Genetics , was co-led ...
(Date:4/17/2014)... of Experimental Biology and Medicine a ... and Paul Kenis in the Institute of Genomic ... of Illinois Urbana-Champaign describe their recent work on ... variety of cell functions including energy metabolism, signaling, ... in regulating normal cellular behavior, redox status has ...
(Date:4/17/2014)... Le Bonheur Children,s Hospital Pediatrician-in-Chief Jon McCullers, MD, ... the April issue of Nature Reviews Microbiology ... Dr. McCullers, a world-renowned infectious disease specialist, ... the University of Tennessee Health Science Center, analyzed ... 1918, 1957 and 1968 pandemics, as well as ...
Breaking Medicine News(10 mins):Health News:New study suggests a better way to deal with bad memories 2Health News:New study suggests a better way to deal with bad memories 3Health News:Innovative strategy to facilitate organ repair 2Health News:Innovative strategy to facilitate organ repair 3Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2
... Education Conference (I/ITSEC) has sold all its ... Center in Orlando. Occupying almost 200,000 square feet, ... simulation technology ever. The I/ITSEC Conference is ... the Orange County Convention Center in Orlando, Florida. ...
... the first robotic assisted surgery to gynaecologic cancer patient in August 2008. ... ... undergo surgery for gynaecological cancers now have an option to have surgery ... back on their feet faster while being just as effective in removing ...
... Smoked During Pregnancy More Than Twice as Likely to ... OAKLAND, Calif., Nov. 5 Babies whose mothers,smoked during ... a cleft,palate or lip as those whose mothers didn,t, ... confirms earlier findings, it is unique because it,did not ...
... Foundation Health Plan,Inc., Kaiser Foundation Hospitals and their ... for the quarter ended September,30, 2008, compared to ... KFHP/H,s operating income in the third quarter ... same quarter last year. Financial market,volatility impacted KFHP/H,s ...
... Increases 18.9% ... Recurring Diluted FAD Per Share Increases ... Third Quarter Investments Total $125 Million, NEWPORT BEACH, Calif., Nov. 4 ... investment activity for the third quarter and the nine months ended,September 30, 2008., ...
... ad has been produced by,an organization not affiliated with ... organization behind the ad., As we have stated ... other religion. But it is wrong for the Mormons ... California through the ballot box, We note Mr. ...
Cached Medicine News:Health News:World's Largest Modeling and Simulation Exhibition Sells Out for '08 2Health News:World's Largest Modeling and Simulation Exhibition Sells Out for '08 3Health News:Singapore Medicine - First in South East Asia to Offer Robotic Surgery for Gynaecologic Cancers 2Health News:Singapore Medicine - First in South East Asia to Offer Robotic Surgery for Gynaecologic Cancers 3Health News:Singapore Medicine - First in South East Asia to Offer Robotic Surgery for Gynaecologic Cancers 4Health News:Singapore Medicine - First in South East Asia to Offer Robotic Surgery for Gynaecologic Cancers 5Health News:Moms' Smoking Linked to Increased Risk of Birth Defects 2Health News:Kaiser Foundation Health Plan and Hospitals Report Third Quarter Results 2Health News:Kaiser Foundation Health Plan and Hospitals Report Third Quarter Results 3Health News:Kaiser Foundation Health Plan and Hospitals Report Third Quarter Results 4Health News:NHP Reports Third Quarter 2008 Earnings 2Health News:NHP Reports Third Quarter 2008 Earnings 3Health News:NHP Reports Third Quarter 2008 Earnings 4Health News:NHP Reports Third Quarter 2008 Earnings 5Health News:NHP Reports Third Quarter 2008 Earnings 6Health News:NHP Reports Third Quarter 2008 Earnings 7Health News:NHP Reports Third Quarter 2008 Earnings 8Health News:NHP Reports Third Quarter 2008 Earnings 9Health News:NHP Reports Third Quarter 2008 Earnings 10Health News:NHP Reports Third Quarter 2008 Earnings 11Health News:NHP Reports Third Quarter 2008 Earnings 12Health News:NHP Reports Third Quarter 2008 Earnings 13Health News:NHP Reports Third Quarter 2008 Earnings 14Health News:NHP Reports Third Quarter 2008 Earnings 15Health News:NHP Reports Third Quarter 2008 Earnings 16
... the cornea for centration of the flap and ... and enhancement cases. The corneal marker has a ... alignment of the flap after treatment. The spatula ... and to flood it back into place following ...
Duckbilled spatula designed to enter a side-port stab incision with tip broad enough to efficiently manipulate the lens nucleus in the anterior chamber. Spatula is useful for rotating and cracking th...
Short handled spatula for use through the side port stab incision. The malleable silver 0.5 mm tip can be shaped to the surgeon's preference for maximum control. Round serrated handle....
... to enter a side-port stab incision ... manipulate the lens nucleus in the ... rotating and cracking the nucleus. It ... and curved shaft which facilitates nuclear ...
Medicine Products: