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Intravenous (IV) Administration of Cempra Pharmaceutical's Solithromycin (CEM-101) Demonstrates Excellent Systemic Tolerability in a Phase 1 Clinical Trial
Date:5/7/2011

am-positive bacteria, including all S. aureus strains such as HA-MRSA and CA-MRSA
  • TAKSTA employs a novel and proprietary PK-PD-based dosing regimen of sodium fusidate that optimizes efficacy and minimizes the risk of resistance development
  • Sodium fusidate is the only compound within the fusidane class and therefore is unlikely to select for cross-resistance to other classes of antibiotics
  • Sodium fusidate's safety has been well documented even when used for long periods of time (over one year) to treat osteomyelitis and other serious infections
  • Sodium fusidate has been used safely in children including neonates in countries where it is marketed

  • About 60 to 80 percent of the 13 million acute skin structure infections that occur in the U.S. each year are attributed to MRSA. There is a growing need for an oral anti-MRSA drug that is safe and effective for acute illness, and is safe for long-term administration.

    About Cempra Pharmaceuticals

    Founded in 2006, Cempra Pharmaceuticals is a privately-held, clinical-stage pharmaceutical company focused on developing antibacterials to address critical medical needs. Two lead products, both in late-stage clinical trials, address the urgent and increasing need for new treatments targeting drug-resistant bacterial infections in the hospital and in the community. Cempra is well-funded and is committed to developing commercially and medically differentiated and novel products that reduce development risk and provide a high financial return. The company is also utilizing its proprietary compound library and chemistry technology to develop novel macrolides without antibacterial activity for non-antimicrobial indications in COPD, chronic inflammatory and GI disorders. Additional information about Cempra can be found at www.cempra.com.

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    SOURCE Cempra Pharmaceuticals
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