Navigation Links
International, Well-Known Scientific Experts Say That New GFT505 Data Unlikely to Have the Potential to Affect the Established Role of Generic Fenofibrate and Bezafibrate in Managing Atherogenic Dyslipidemia
Date:12/16/2009

NEW YORK, December 16 /PRNewswire/ -- International, well-known scientific experts were surprised by the publication of GFT505 (80 mg/day) data presented as "extremely promising."[1] More than 50 internationally recognized expert scientists and clinicians critically reviewed these data. These experts reaffirmed the continuing role of generic lipid-modifying treatments, fenofibrate and bezafibrate, in treating atherogenic dyslipidemia, which is commonly observed in patients with metabolic syndrome and type 2 diabetes and is characterized by elevated triglycerides and low 'good' high-density lipoprotein (HDL) cholesterol. Published clinical data also already indicate a potential role for fenofibrate in treating non-alcoholic fatty liver disease.[1]

    Reviewing published evidence, these experts argued that:

    - Elevated triglycerides (>150 mg/dL) are decreased by 43% with
      generic fenofibrate[2] and 32% with generic bezafibrate[2]
    - Low HDL cholesterol (<40 mg/dL) is increased by 18%[3],[4]

Either agent is approximately two-fold more effective than 80 mg of GFT505, an investigational agent currently in early phase II development.[5]

                      GFT505     Fenofibrate        Bezafibrate

    Triglycerides      -21%     -43 percent[6]     -32 percent[7]
    (>150mg/dL)

    HDL-C (<40mg/dL)    +9%    +18,8 percent[8]   +17,9 percent[9]

Published data show a potential role for fenofibrate in treating non-alcoholic fatty liver disease, significantly decreasing the proportion of patients with liver dysfunction.[1]

Fenofibrate significantly reduced both liver enzymes, alanine amino transferase (ALT) and aspartate amino transferase (AST), unlike GFT505.[10]

Commenting on these data, these experts said: 'These new data show that GFT505 is unlikely to have the potential to replace generic fenofibrate and bezafibrate in treatin
'/>"/>

SOURCE international experts
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Arno Therapeutics, Inc. Completes $18 Million Financing and Reverse Merger with Laurier International, Inc.
2. Medizone International, Inc. (MZEI.PK): Trials of the AsepticSure Hospital Sterilization System Have Begun
3. Chindex International, Inc. to Report Second Quarter Fiscal 2010 Financial Results
4. Chindex International, Inc. Reports Second Quarter and First Half Fiscal 2010 Financial Results
5. Natural Alternatives International, Inc. Announces Filing of Patent Infringement Lawsuit
6. New Database from ANSI, AAMI, ASTM International, and DIN Provides Centralized Source of Information for Medical Device Professionals
7. DAVISCO Foods International, Inc. and MEGGLE Group Announce a Joint Venture for the Production of Pharmaceutical Lactose.
8. Lexington International, LLC Receives 2009 U.S. Presidents E Award Recognizing its Export Achievements
9. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
10. Avicena Scientific Collaborator Advances Program for Using Energy Enhancing Molecules to Treat Neuromuscular Diseases
11. Boston Scientific Announces Schedule for European Society of Cardiology Congress 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... July 28, 2015   DigiPath Labs , the ... combining efforts with True North Laboratory of ... , a leading global supplier of diagnostic solutions for ... Romer Labs, rapid diagnostic test kits to screen ... "This joint effort is expected to result ...
(Date:7/27/2015)... CTI BioPharma Corp. (NASDAQ and MTA: CTIC) ... quarter 2015 financial results on Thursday, August 6, 2015, ... the announcement, members of the management team will host ... provide a general corporate update at 4:30 p.m. EDT ... obtained as follows: Thursday, August 6 1:30 ...
(Date:7/27/2015)... , July 28, 2015   Regeneron Pharmaceuticals, ... a new global collaboration to discover, develop and commercialize ... immuno-oncology. As part of the agreement, the two companies ... (PD-1) inhibitor currently in Phase 1 testing and plan ... candidates based on ongoing, innovative preclinical programs. ...
Breaking Medicine Technology:DigiPath Labs Partners with Romer Labs to Validate Food-Borne Pathogen and Mycotoxin Testing Solutions for Cannabis 2DigiPath Labs Partners with Romer Labs to Validate Food-Borne Pathogen and Mycotoxin Testing Solutions for Cannabis 3CTI BioPharma to Report Second Quarter 2015 Financial Results on August 6, 2015 2Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 2Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 3Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 4Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 5Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 6Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 7Regeneron and Sanofi Launch Major New Immuno-Oncology Collaboration 8
... Reportlinker.com announces that a new market research ... Assistive Devices for Special Needs: Technologies and ... THIS REPORT CONTAINS ... for several categories of special needs, including cognitive ...
... Reportlinker.com announces that a new market research ... Triple Analysis: Colorectal Cancer, Lung Cancer and ... This triple analysis focuses on cancer drug ... Lymphoma. Each of these three individual parts is ...
Cached Medicine Technology:Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 2Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 3Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 4Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 5Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 6Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 7Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 8Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 9Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 10Reportlinker Adds Assistive Devices for Special Needs: Technologies and Global Markets 11Reportlinker Adds Triple Analysis: Colorectal Cancer, Lung Cancer and Lymphoma 2Reportlinker Adds Triple Analysis: Colorectal Cancer, Lung Cancer and Lymphoma 3Reportlinker Adds Triple Analysis: Colorectal Cancer, Lung Cancer and Lymphoma 4Reportlinker Adds Triple Analysis: Colorectal Cancer, Lung Cancer and Lymphoma 5
(Date:7/28/2015)... , ... July 28, 2015 , ... Fertility specialist ... as a “Top Doctor 2015” by Atlanta Magazine. In Atlanta Magazine's annual Top Doctors ... hundreds of her esteemed colleagues and peers in the metro area as one of ...
(Date:7/28/2015)... ... July 28, 2015 , ... Every summer, the public is reminded ... caution when lighting fireworks in their own neighborhoods. Unfortunately, according to a recent report ... 3, 2015 USA Today article " Eye Injuries Caused by Fireworks Doubled in Last ...
(Date:7/28/2015)... , ... July 28, 2015 , ... A new study ... Easy Fibromyalgia, Study Says " sheds light on a possible new treatment option for ... two months of regular HBOT sessions, at least five per week, patients experienced a ...
(Date:7/28/2015)... ... July 28, 2015 , ... A ... Mets' David Wright's Spinal Stenosis Injury" discussed baseball player David Wright’s spinal stenosis ... acquired lumbar stenosis, brought on by degenerative changes in the spine, rather than ...
(Date:7/28/2015)... ... July 28, 2015 , ... The PULs ... Sudden Death, or Angina), many of whom are missed by conventional evaluation ... with active yet undetected sub-clinical disease, who are at risk of experiencing a ...
Breaking Medicine News(10 mins):Health News:Atlanta Fertility Specialist Named Top Doctor in Atlanta Magazine 2Health News:Atlanta Fertility Specialist Named Top Doctor in Atlanta Magazine 3Health News:Carlsbad Ophthalmologist Discusses Doubling of Fireworks Eye Injuries in Three Year Span 2Health News:Carlsbad Ophthalmologist Discusses Doubling of Fireworks Eye Injuries in Three Year Span 3Health News:Recovery Specialists Discuss How Oxygen Therapy Can Ease Fibromyalgia 2Health News:Recovery Specialists Discuss How Oxygen Therapy Can Ease Fibromyalgia 3Health News:Spine Surgeon Weighs in on Uncertain Future Baseball Career Future for David Wright 2Health News:Spine Surgeon Weighs in on Uncertain Future Baseball Career Future for David Wright 3Health News:Utility of a novel coronary artery disease biomarker algorithm in modifying physician adherence to guideline therapy presented at 20th World Congress on Heart Disease 2
... estimates savings of more than $60 million over 11 years ... of air bags and seat belts significantly reduces injuries to ... and also lowers in-hospital death rates, injury severity and hospital-acquired ... It also suggests that optimal use of air bags could ...
... Ill. Recent studies have linked sleep loss ... obesity, diabetes, high blood pressure and stroke. The ... discussed by more than 5,000 scientists and sleep specialists ... Associated Professional Sleep Societies convenes at the Baltimore Convention ...
... The Joint Annual Meeting of the American Society of Plant ... y Biologia Molecular de Plantas will be held June 2225, ... , A major theme of this year,s annual meeting ... in the America,s. Presentations will also focus on ...
... clinicians identify best treatment ... risk of heart disease, BIRMINGHAM, Ala., May 28 ... its VAP,Cholesterol Test in booth No. 4202 at the American ... June 6 -,10, 2008, at the Moscone Convention Center in ...
... China, May 28 /Xinhua-PRNewswire-FirstCall/ -- China Sky One,Medical, ... or ,the Company,), a,manufacturer, marketer and distributor of ... that it has engaged MSPC,Certified Public Accountants and ... May 21, 2008. The Company terminated its,contract with ...
... to complete electronic records, CINCINNATI and MONTREAL, ... STRM ) and Emergis Inc., a TELUS company,today ... and,workflow solution at the eight hospitals representing the ... McGill University,Health Centre (MUHC). The module is integrated ...
Cached Medicine News:Health News:Air Bags-Seat Belts Cut Injuries, Deaths, Costs 2Health News:Experts to discuss sleep science and the health risks of sleep disorders in Baltimore this June 2Health News:Experts to discuss sleep science and the health risks of sleep disorders in Baltimore this June 3Health News:ASPB engages Latin America colleagues at Annual Meeting in Merida, Mexico June 22-25 2Health News:ASPB engages Latin America colleagues at Annual Meeting in Merida, Mexico June 22-25 3Health News:Atherotech to Exhibit The VAP Test at ADA 2008 Meeting in San Francisco 2Health News:China Sky One Medical, Inc. Engages Moore Stephens as New Independent Auditor 2Health News:China Sky One Medical, Inc. Engages Moore Stephens as New Independent Auditor 3Health News:Streamline Health's Document Management Solution Integrated into Oacis, Allowing Clinicians to Access Patients' Information - Either Scanned or Electronic 2Health News:Streamline Health's Document Management Solution Integrated into Oacis, Allowing Clinicians to Access Patients' Information - Either Scanned or Electronic 3Health News:Streamline Health's Document Management Solution Integrated into Oacis, Allowing Clinicians to Access Patients' Information - Either Scanned or Electronic 4Health News:Streamline Health's Document Management Solution Integrated into Oacis, Allowing Clinicians to Access Patients' Information - Either Scanned or Electronic 5
White Standard Girdle...
This compression garment can be used immediatlely following Abdominoplasty, Tram Flap, Abdominal Liposuction, Lipoplasty, Suction Lipectomy, Stomach Liposuction, Liposculpture and Tummy Tuck procedur...
Below Knee Girdle, High Waist...
Short Girdle, Mid-thigh, Front Closure...
Medicine Products: