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Interim Data Announced for BIBF 1120 as Compared to bevacizumab in Combination Chemotherapy in Metastatic Colorectal Cancer
Date:9/27/2011

izumab Plus mFOLFOX6 In Patients With Metastatic Colorectal Cancer.  Oral presentation, European Cancer Organization Congress, Stockholm, September 2011.

3.  Hilberg F et al. BIBF1120: Triple angiokinase inhibitor with sustained receptor blockade and good anti-tumor efficacy. Cancer Research 2008;68(12): 4774-4782.

4.  Van Cutsem et al.  A Phase I/II, open-label, randomised study of BIBF 1120 plus mFOLFOX6 compared to bevacizumab plus mFOLFOX6 in patients with metastatic colorectal cancer. Clinical Trial Protocol (1199.51), Revised 23 June 2009.

5.  American Cancer Society.  Cancer Facts and Figures: 2011.  Available at: http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-029771.pdf.  Last accessed September 15, 2011.

6.  Folkman N. Clinical Applications of Research on Angiogenesis. New England Journal of Medicine 1995;333: 1757-1763.

7.  Ellis, L.M. and Hicklin, D.J. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nature Reviews Cancer 2008;8: 579-591.


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