Navigation Links
Intercept Pharmaceuticals and Servier Announce Agreement for Intercept's TGR5 Research Program in Type 2 Diabetes
Date:8/9/2011

omplement those of other classes of marketed diabetes drugs."

About TGR5

TGR5 (GPR131) is a cell-surface G protein coupled receptor that is regulated by bile acids. Bile acids are known to be key regulators of lipid, glucose and overall energy metabolism. This receptor has been shown to be a key regulator of energy homeostasis through induction of the incretin GLP-1 in the intestine with resulting insulin sensitizing effects, as well as through activation of metabolic pathways in brown adipose tissue and skeletal muscle that drive energy expenditure and resulting resistance to weight gain. TGR5 is also involved in the modulation of cytokine production by immune cells, potentially playing a role in the control of inflammation.

About Intercept Pharmaceuticals

Intercept is a biotechnology company focused on discovering and developing small molecule drugs for the treatment of chronic liver and metabolic diseases.  The company's most advanced programs are focused on the development of modified bile acids that are selective for FXR, a nuclear receptor, and TGR5. Bile acid signaling through these receptors regulates key aspects of lipid, glucose and overall energy metabolism, while also serving to maintain the functional integrity of the liver, intestine and kidneys, organs that are exposed to bile acid flux. For more information about Intercept, please go to www.interceptpharma.com and for information about Intercept's lead investor, Genextra S.p.A., please go to www.genextra.it. CONTACT: Mark Pruzanski, M.D. or Barbara Duncan, both of Intercept Pharmaceuticals, +1-646-747-1000.

About Servier

Servier is the leading independent pharmaceutical company in France with sales worldwide reaching EUR3.7 billion in 2010. The Servier Research Group is established in 140 countries with its main therapeutic products treating ty
'/>"/>

SOURCE Intercept Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Intercept Pharmaceuticals Announces Positive Phase II Results for Obeticholic Acid (INT-747) as Monotherapy in Primary Biliary Cirrhosis
2. Dainippon Sumitomo Pharma and Intercept Pharmaceuticals Announce Agreement to Develop and Commercialize Obeticholic Acid (INT-747) for Chronic Liver Disease
3. Initiation of FLINT Announced by NIDDK: Study of Intercept Pharmaceuticals Obeticholic Acid (INT-747) in NASH
4. Intercept Pharmaceuticals to Collaborate With NIDDK on Study of Obeticholic Acid (INT-747) in Nonalcoholic Steatohepatitis (NASH)
5. Intercept Pharmaceuticals Raises $25 Million Series B Financing
6. Intercept Pharmaceuticals Announces Positive Phase II Results for INT-747 as a Treatment for Primary Biliary Cirrhosis
7. Intercept Pharmaceuticals FXR Agonist INT-747 Meets Primary Endpoint in a Phase II Clinical Trial in Type 2 Diabetic Patients with Nonalcoholic Fatty Liver Disease
8. Lexicon Pharmaceuticals Reports on Clinical Program Status and 2011 Second Quarter Results
9. K-V Pharmaceutical Company Announces the Completion of the Sale of Nesher Pharmaceuticals, Inc. its Generic Pharmaceutical Business
10. Avanir Pharmaceuticals Reports Fiscal 2011 Third Quarter Financial Results
11. Auxilium Pharmaceuticals, Inc. Announces Promotion of Dr. James P. Tursi to Chief Medical Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... N.C. , July 11, 2014 ... pharmaceutical marketing and, consequently, organizations are turning to ... patients. As part of this evolving ... important to educate, communicate and engage patients throughout ... awareness to patient empowerment. By mapping the patient ...
(Date:7/11/2014)... Research and Markets  has announced the ... report to their offering. ... a hollow needle commonly used with a syringe to ... fluids from it. A hypodermic needle is used for ... cannot be ingested. Hypodermic needles are broadly classified into ...
(Date:7/11/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/tjlw9k/immunoprotein ) has ... Testing Market - Forecasts to 2019: Expected to ... is expected to be valued at USD 4,943.0 ... http://photos.prnewswire.com/prnh/20130307/600769 The ... according to immunoprotein types which include immunoglobulins, complement ...
Breaking Medicine Technology:New Study Uses Six-Step Patient Journey as Framework for Consumer-Focused Marketing Opportunities 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2
(Date:7/13/2014)... optical imaging device developed at Cedars-Sinai can provide ... the brain and are a classic sign of ... conducting a clinical trial in Australia. , The ... an oral presentation at the Alzheimer,s Association International ... invited by conference organizers to participate in a ...
(Date:7/13/2014)... OH (PRWEB) July 13, 2014 Wright ... bellwether trial has been scheduled in July of 2015, ... Lipitor lawsuits are in the discovery process ... Richard M. Gergel is presiding over the multidistrict litigation ... filed on behalf of individuals who allege that they ...
(Date:7/13/2014)... ECS is being founded by Seattle ... a special needs child, I have become keenly aware ... contemporary special education resources and evidence-based instruction. Emerald City ... families in the Seattle metro area that are looking ... We welcome the opportunity to serve our community and ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 According to ... this is a comprehensive program that teaches people how ... peripheral neuropathy without medications. This program also provides ... symptoms of peripheral neuropathy , including numbness, prickling, burning, ... its review that this home treatment program can help ...
(Date:7/12/2014)... According to the new market research ... Systems, and Naval Systems) - Global Forecasts and Analysis ... Surveillance Radar market are estimated to be $6.08 billion ... of 5.97% to reach $8.61 billion by 2020. , ... figures spread through 161 pages and in-depth TOC on ...
Breaking Medicine News(10 mins):Health News:Study of noninvasive retinal imaging device presented at Alzheimer's conference 2Health News:Study of noninvasive retinal imaging device presented at Alzheimer's conference 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 2Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 3Health News:Lipitor Lawsuits Move Forward With Scheduling Of First Bellwether Trial 4Health News:New Private School, Emerald City School, Founded in Downtown Seattle Now Accepting 1st to 6th Grade Students Who Learn Differently 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 2Health News:The Peripheral Neuropathy Program Review Exposes Randall Labrum's Peripheral Neuropathy Treatment Program – Vkool.com 3Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Security and Surveillance Radar Market Estimated to Reach $8.61 Billion by 2020 – New Report by MarketsandMarkets 4
Fatehpur Sikri, Mughal Emperor Akbar's dream city, has come up some new finds, thanks to the labourious// excavatory work of the Archaeological Survey of India (ASI). ,According to Munazar Ali, a mo...
... from the University of Lund in Sweden have conducted ... of type 2 diabetes // . ,Exposure ... asthma, diabetes and many cancers. ,High levels of ... dichloro-diphenyl-trichloro-ethane or DDT in the blood of diabetic patients ...
... practices, massive migration and low awareness there has been ... disease // amongst the tribal community, living close to ... Ganjam, Kendrapara, Balasore Nuapada, Koraput, Rayagada, Phulbani and Sundargarh ... a challenge to the Government of Orissa. The percentage ...
... that loud noise can increase the risk of heart attacks ... to the noise related to the workplace as well as ... found that this noise had a physiological effect on the ... Medicine, Epidemiology and Health Economics at Charite University Medical Centre ...
... to have succumbed to pneumonia in the earthquake affected ... The severe cold in the earthquake-hit areas is reported ... hundred people. The inadequate medical facilities in the quake-hit ... pneumonia. ,'More than 30 people have been reported ...
... Beer as it is, is a very popular drink in Europe ... there have manufactured a healthy beer called karla //, which they ... cancer. ,The beer is made form herbs and also ... also with a lower alcohol percentage. Chemists claim that the sale ...
Cached Medicine News:Health News:High Decibel Levels Raise Heart Disease Risk 2Health News:Pneumonia Claims 30 Lives In Pakistan 2
One channel transcranial Doppler...
Locates flow easily, and identifies flow depth and direction for multiple vessels simultaneously....
... an advanced Doppler system that allows non-invasive ... body. This method of measurement is particularly ... blood to the brain. , ,TCD is ... problems such as vasospasm and intracranial stenosis. ...
Swiss Watchmaker Forceps, 4" extra-long precision ground points....
Medicine Products: