Navigation Links
InterMune Reports Presentation of Triple Combination Study of ITMN-191 at European Association for the Study of the Liver (EASL)
Date:4/24/2009

- Results inform selection of doses, regimens to be explored in Phase 2b study -

-- Phase 2b program anticipated to begin in summer 2009 --

COPENHAGEN, April 24 /PRNewswire-FirstCall/ -- InterMune, Inc. (Nasdaq: ITMN) today announced that results from a 14-day Phase 1b clinical study of ITMN-191 (R7227) in combination with the current standard of care were presented today by Stefan Zeuzem, M.D., of the J.W. Goethe University, Frankfurt, Germany, in an oral presentation at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL) in Copenhagen, Denmark. The study explored the use of ITMN-191 in combination with Pegasys(R) (peginterferon alfa-2a) and Copegus(R) (ribavirin) for 14 days of treatment in hepatitis C virus (HCV) treatment-naive patients infected with HCV genotype 1. ITMN-191 is an HCV protease inhibitor being developed in collaboration with Roche.

Among the highlights of his presentation, Dr. Zeuzem reported:

  • The combination of ITMN-191 plus the standard of care for 14 days resulted in rapid and sustained reductions in HCV RNA.
  • Substantial antiviral activity was observed in both the q8h and q12h dosing cohorts; the most rapid declines in HCV RNA occurred in the ITMN-191 900 mg q12h dosing cohort.
  • Viral rebound was not observed in any patient receiving treatment with ITMN-191 plus Pegasys and ribavirin.
  • ITMN-191 plus standard-of-care therapy was safe and generally well tolerated.
  • The findings support the continued evaluation of ITMN-191-based combination regimens of twice-daily and three-times-daily dosing in patients with chronic HCV infection.

Dr. Zeuzem, protocol chair of the study, said, "Based on the t
'/>"/>

SOURCE InterMune, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. InterMune Announces Approval of Clinical Trial Authorization for Phase 1b Trial of ITMN-191
2. InterMune Announces Start of Phase 1b Trial of ITMN-191
3. InterMune Announces Top-Line Results of Phase 1b Trial of ITMN-191 (R7227) and Provides Program Update
4. InterMune Provides Additional Information on ITMN-191 (R7227) MAD Study Results
5. InterMune Announces Progress on Pirfenidone in IPF
6. InterMune Announces Receipt of Fast Track Designation for Pirfenidone From FDA
7. InterMune Announces Start of 14-Day Triple Combination Study of ITMN-191 in Patients With Chronic Hepatitis C
8. Roche, InterMune and Pharmasset Announce Initiation of INFORM-1, the First Dual-Combination Clinical Trial with Oral Antivirals in Hepatitis C
9. InterMune to Report Top-Line Results of Triple Combination Study of ITMN-191 in January 2009
10. InterMune to Conduct Conference Call and Webcast to Discuss Results of Triple Combination Study of ITMN-191
11. InterMune to Announce Results of Phase 3 CAPACITY Program of Pirfenidone in IPF Tomorrow, February 3
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 2014 Research and Markets has ... Medical X-ray Film Industry Report 2014" report to ... Global And Chinese Medical X-Ray Film Industry ... the current state of the Global medical X-ray film ... The report provides a basic overview of the industry ...
(Date:7/11/2014)... , July 11, 2014 Research and ... Hypodermic Needles Market 2014-2018" report to their offering. ... A hypodermic needle is a hollow needle commonly used ... or or to extract fluids from it. A hypodermic ... to inject substances that cannot be ingested. Hypodermic needles ...
(Date:7/11/2014)... 2014  Australian drug delivery company, Phosphagenics Limited (ASX: ... A$19.3 million via a placement of A$16.3 million to ... U.S., Asia and ... purchase plan (SPP) to be offered to existing shareholders. ... two tranches. "This capital raising positions us ...
Breaking Medicine Technology:Global and Chinese Medical X-ray Film Industry Report 2014 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 2Global Hypodermic Needles Market 2014-2018: Key Vendors are Becton, Dickinson and Co, Covidien, Retractable Technologies and Terumo Corp. 3Phosphagenics' A$19.3 million Capital Raising 2Phosphagenics' A$19.3 million Capital Raising 3
... Unilife Corporation ("Unilife" or the "Company") (NASDAQ: ... financial results for the fourth quarter and fiscal year ... Completed construction of new global headquarters ... relocated entire staff (December 2010) Appointed Dr. Ramin ...
... Watson Pharmaceuticals, Inc. (NYSE: WPI ), a leading ... and Chief Executive Officer, will provide an overview and update ... Healthcare Conference on Tuesday, September 13, 2011 at 1:35 pm ... York City. The presentation will be webcast live and can ...
Cached Medicine Technology:Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 2Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 3Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 4Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 5Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 6Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 7Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 8Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 9Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 10
(Date:7/14/2014)... Downers Grove, IL (PRWEB) July 14, 2014 ... and online marketing company for mental health professionals, ... Professional Counselors Association of North Carolina (LPCANC). ... extend their online marketing solutions to LPCANC members, ... the past 7 years, we have been dedicated ...
(Date:7/14/2014)... Spine Team Texas continues ... diagnosis to treatment and recovery. Currently all physical therapists ... or training for certification in The McKenzie Method. Two ... the extensive program. , “We require certification of our ... in better outcomes for spine pain patients,” said Mark ...
(Date:7/14/2014)... New research and analysis from the national ... examines toxic ingredients in tampons, a product used ... chemicals that may be found in the product’s absorptive ... put women’s health at risk. , According to ... , the potential impact of toxic chemical exposure from ...
(Date:7/13/2014)... Save the Date for the 2014 Art & ... , BOXWOODS & BowTies “A Modern Twist on Southern Traditions” ... Women’s Board of Wolfson Children’s Hospital will host its ... their ongoing commitment to raising funds for the advancement of ... The 2014 Art & Antiques Show is a three-day show ...
(Date:7/13/2014)... 14, 2014 The special two-day sale starts ... Sublime Beauty®. Use coupon code 20SCRUB at the webstore checkout. ... who tries the Fresh Citrus Scrub falls in love with ... is a perfect little cleanser for face, but can also ... beads that help to exfoliate with pleasure, clean pores and ...
Breaking Medicine News(10 mins):Health News:TherapySites Partners With the Licensed Professional Counselors Association of North Carolina to Make Online Marketing Available to All Therapists 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:New Patent Analysis Shows Toxic Risk From Tampons 2Health News:New Patent Analysis Shows Toxic Risk From Tampons 3Health News:New Patent Analysis Shows Toxic Risk From Tampons 4Health News:New Patent Analysis Shows Toxic Risk From Tampons 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 4Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 6Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 7Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 8Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 9Health News:Discover the Favorite Sublime Beauty® Citrus Scrub: Special "Two-Day Only" Sale 2
... conducted by Professor William Ledger, a fertility expert at ... of producing //a baby through in-vitro fertilisation and the ... study states that the benefits of providing free fertility ... to the government. ,He along with a ...
... is a bacteria resistant to certain antibiotics. This bacteria ... systems, especially in hospitals and nursing homes and is ... like the Netherlands, Sweden, and Norway, where MRSA has ... now facing an increase in incidence with the rates ...
... of infecting 400 Libyan children with AIDS, five Bulgarian Nurses ... //in the Court of Appellations in Tripoli. ... hospital aids made the outbreak possible since all the instruments ... that outbreak was made by them knowingly. ,Re-assessment ...
... seeking various opinions on the issue of doctors being allowed ... a ban. , In its new draft guidance, ... them that the relationship would usually be considered inappropriate. ... the guidelines acknowledge that social circumstances may demand ...
... of Medicine and colleagues finds it’s better to inform ... dizzy feel of nausea previously. ... to adversity – both subjectively and physiologically,’ said lead ... can benefit people greatly.’ ,The study, designed ...
... found in cannabis, also known as hashish or marijuana, ... it on rats //. ,Yehoshua Maor, a ... created a synthetic version of a minor cannabis constituent ... lowering blood pressure, reported science portal The News Medical. ...
Cached Medicine News:Health News:Free IVF Treatment Could Prove Beneficial to the Society And Its Economy 2Health News:Super-bug MRSA Getting Fitter And Out of Control 2Health News:Precautious Measure Help Tolerate Nausea In Patients 2Health News:Precautious Measure Help Tolerate Nausea In Patients 3
... Workstations provide comprehensive neurological monitoring in ... unit to accurately access your patients ... 15 years experience, and a long ... neurological monitoring systems have a proven ...
Vikingselect™ Intra-Operative Monitoring (IOM)....
The Nicolet Bravo™ is a Multi-application system that can configure to meet the needs of neurophysiology department....
... system especially designed for surgical monitoring and ... channels and is equipped with two headboxes ... can be independently configured as either a ... Endeavor amplifiers are based on the Firewire ...
Medicine Products: