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Intellect Neurosciences, Inc. Announces Independent Studies on Copper Binding Properties of its Lead Candidate OXIGON(TM)
Date:3/3/2009

Studies Support Potential for Alzheimer's Disease and Other Neurodegenerative Diseases

NEW YORK, March 3 /PRNewswire-FirstCall/ -- Intellect Neurosciences, Inc. (OTC Bulletin Board: ILNS), a biopharmaceutical company focused on development of disease-modifying therapeutic agents for Alzheimer's disease ("AD"), announced today that the chemical structure of OXIGON(TM) (indole-3-propionic acid) has been independently shown to form copper complexes. This discovery provides important insight into how the drug neutralizes the neurotoxicity of Alzheimer's beta-amyloid toxin, previously reported by several investigators. Also, it provides further support that OXIGON(TM) has broad potential for use in the treatment of other neurodegenerative conditions, such as Parkinson's disease, where metal binding is believed to induce the pathological aggregation of proteins. The discovery regarding the metal binding properties of OXIGON(TM) was reported by Professor Liang Hong and colleagues from Guangxi Normal University, Guilin, China, in February 2008 in an online publication, CJI.

Intellect is developing OXIGON(TM) as a drug candidate for AD. The drug, which has disease-modifying potential by preventing metal-dependent aggregation, neurotoxicity and deposition of beta amyloid, has been tested in human Phase I trials for safety and tolerability at various doses and different durations in a total of 90 elderly, healthy volunteers. The development of OXIGON(TM) as a drug candidate for AD has been supported in part by the National Institute of Aging, the BIRD Foundation and The Institute for the Study of Aging. The Company is seeking additional investments to support initiation of Phase II clinical trials for OXIGON(TM) in Alzheimer's patients.

Dr. Daniel Chain, Intellect's Chairman and CEO commented: "We were very interested to learn that OXIGON(TM) has metal binding properties." Dr. Chain added: "These data fit perf
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SOURCE Intellect Neurosciences, Inc.
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