Navigation Links
Intarcia Presents Positive ITCA 650 Phase 2 Study Results for Type 2 Diabetes at EASD
Date:9/22/2010

40 mcg/day

60 mcg/day

80 mcg/dayMean baseline HbA1c (%)

7.96

7.79

8.05

8.03Mean week 24 HbA1c (%)

7.07

6.93

6.67

6.67Mean HbA1c change at week 24

-0.89

-0.86

-1.38

-1.36HbA1c  < 7% at week 24

60%

71%

73%

79%Mean weight change at week 24 (lbs)

-1.8

-7.9

-6.8

-7.7"The reductions in HbA1c and weight are substantial, especially for a group of patients on metformin-only background therapy with baseline HbA1c levels at 8.0 percent.  We look forward to evaluating optimized dose regimens of ITCA 650 in broader patient populations in the phase 3 program," Graves said.

ITCA 650 therapy in the phase 2 trial was administered for the 90-day treatment period with a single insertion of ITCA 650 on day 1 and removal on or around day 90. The extension phase of the 2 trial evaluated higher doses of ITCA 650 using a single device to deliver 3 months of treatment. The phase 3 study planned for early 2011 will evaluate treatment regimens involving initial 12-week ITCA 650 dosing at 20 mcg/day transitioning to 60 mcg/day thereafter using even longer duration ITCA 650 devices.

A downloadable version of the ITCA 650 phase 2 presentation from EASD is available on the Intarcia corporate website at: http://www.intarcia.com/media_presentations.html

About ITCA 650ITCA 650 therapy for type 2 diabetes consists of DUROS continuous subcutaneous delivery of exenatide. The DUROS delivery technology comprises the DUROS device, a matchstick-size, miniature osmotic pump that is inserted subcutaneously to provide continuous and consistent drug therapy. Intarcia's proprietary formulation technology that maintains stability of therapeutic proteins and peptides at human body temperature for extended periods of time.

The DUROS technology can
'/>"/>

SOURCE Intarcia Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes
2. Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals
3. Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference
4. EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer
5. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
6. Anadys Pharmaceuticals Presents Preclinical Results on ANA598, a Non-Nucleoside Inhibitor of the NS5B Polymerase, at the 14th International Symposium on Hepatitis C Virus and Related Viruses
7. CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein
8. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
9. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
10. Wyeth Presents Phase 3 Fracture Data for Bazedoxifene, an Investigational Therapy for Osteoporosis
11. Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)...  Pharmaceutic Labs announces its official status as ... the FDA,s Drug Quality and Security Act. To ... to Current Good Manufacturing Practice (CGMP) and increased ... highest standards of CGMP 21 CFR Part 210 ... with FDA regulations and ensure patient safety, Pharmaceutic ...
(Date:5/28/2015)... INDIANAPOLIS , May 28, 2015  Eli ... final results of the Phase III PROCLAIM trial ... presentation at the American Society of Clinical Oncology ... . PROCLAIM was a randomized, Phase III superiority ... lung cancer (NSCLC), which evaluated Lilly,s ALIMTA ® ...
(Date:5/28/2015)... Research and Markets( http://www.researchandmarkets.com/research/rjpc7h/2015_strategies ) has ... in the US Ancillary Hospital Locations (ERs, ORs, ... offering. This new 973-page report contains ... diagnostic testing markets outside the main hospital laboratory ... of the market dynamics, size, growth, regulatory requirements, ...
Breaking Medicine Technology:PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 2PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 3PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 4PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 5PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 6PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 7PROCLAIM Final Trial Results to be Presented at ASCO Annual Meeting 8Strategies in the US Ancillary Hospital Locations (ERs, ORs, ICUs) Diagnostic Testing Market 2015-2020 2
(Date:5/28/2015)... Hexagon Geospatial is pleased to announce that ... engineering, spatial data and mapping services, is using Hexagon ... clouds for urban change assessments in Bernalillo County, New ... Spatial Data Division implemented a countywide approach to generating ... by a variety of different digital aerial camera systems, ...
(Date:5/28/2015)... May 28, 2015 lifeIMAGE ... round of financing led by Cambia Health Solutions ... dedicated to transforming health care by creating a person-focused ... most utilized network for exchanging medical imaging, will use ... base, increase the breadth of its network capabilities and ...
(Date:5/28/2015)... 28, 2015 WebWatcher, the ... their partnership with BeSure Consulting to help ... The partnership will combine BeSure Consulting’s ... parental monitoring software solution. , Led by ... Consulting's passion is concentrated on teaching law ...
(Date:5/28/2015)... PA (PRWEB) May 28, 2015 A ... and adventures. Each item on the bucket ... impossible events, experiences and tasks that the owner wants ... no right or wrong when it comes to making ... a business, writing poems, publishing a book, seeing the ...
(Date:5/28/2015)... Ask not what your racquet can do for you ... your racquet. With the launch of their new digital campaign, ... astonishing tricks and unique skill to HEAD Pro Players and ... trick artist playfully demonstrates how to gain more control over ... but also challenges tennis enthusiasts everywhere to join the show. ...
Breaking Medicine News(10 mins):Health News:Hexagon Geospatial Supports Urban Change Detection Programs in New Mexico 2Health News:Hexagon Geospatial Supports Urban Change Detection Programs in New Mexico 3Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 2Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 3Health News:Cambia Health Solutions Leads New Round of Investment in lifeIMAGE 4Health News:WebWatcher Partners with BeSure Consulting 2Health News:WebWatcher Partners with BeSure Consulting 3Health News:Tennis Artist Baffles Novak Djokovic - HEAD Launches Trick Shot Campaign “Frame & Play” 2
... NEWARK, Calif., June 24 Novasys Medical, Inc., a ... that as of July 1, 2009, First Coast Service ... serving over 3 million beneficiaries in Florida, Puerto Rico ... Renessa(R) treatment for women with stress urinary incontinence (SUI) ...
... by Surescripts Use Allscripts Electronic Health Record and ePrescribing ... (Nasdaq: MDRX ) today congratulated three of ... "E-Prescriber of the Year" award winners announced Monday by ... Awards. Safe-Rx is an annual award that recognizes how ...
... June 24 /PRNewswire-FirstCall/ - Hard to Treat Diseases (HTDS.PK) ... is in the process of recovering intellectual property (IP) ... the Company. , The Company retained a USA based ... which the current management, preferred shareholder and its corporate ...
... Inspired Life, , , WASHINGTON, June 24 ... that seeks to safeguard patients through effective mediation assuring ... their financial stability relative to their diagnosis of life ... that Elizabeth Edwards, an accomplished attorney, successful author and ...
... HIPAA era has arrived; ZixCorp executive offers advice for ... June 24 Zix Corporation (ZixCorp(R)) (Nasdaq: ... for email encryption, today announced that ZixCorp Vice President ... to discuss the recent amendments to the healthcare privacy ...
... , Chocolate and Candy Remain Recession Resistant , ... flexibility and variety, confectionery makers are thinking outside the bar ... drive consumer purchasing over the next five years, according to ... Even in economic uncertainty, the industry continues to post gains. ...
Cached Medicine News:Health News:First Coast Medicare to Provide Case by Case Reimbursement for the Renessa(R) Treatment for Incontinence in Women 2Health News:First Coast Medicare to Provide Case by Case Reimbursement for the Renessa(R) Treatment for Incontinence in Women 3Health News:Allscripts Clients Win Half of National 'E-Prescriber of the Year' Awards 2Health News:Allscripts Clients Win Half of National 'E-Prescriber of the Year' Awards 3Health News:Allscripts Clients Win Half of National 'E-Prescriber of the Year' Awards 4Health News:Allscripts Clients Win Half of National 'E-Prescriber of the Year' Awards 5Health News:Hard To Treat Diseases (HTDS.PK) To Regain Intellectual Property (IP) Ownership 2Health News:Hard To Treat Diseases (HTDS.PK) To Regain Intellectual Property (IP) Ownership 3Health News:Elizabeth Edwards to Deliver Keynote Address at Patient Advocate Foundation's 10th Annual Patient Congress 2Health News:Zix Corporation Addresses New HIPAA Regulations 2Health News:Zix Corporation Addresses New HIPAA Regulations 3Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 2Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 3Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 4Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 5Health News:Confectionery Industry Forecast Is Sweet: Globally Inspired Flavors, Eco-Friendly and Health Minded Trends Lead New Product Innovations 6
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Temporary mini-type 1/1 (mm), opening width 5.0 mm and length 6 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Fenestrated large type 1/1 (mm), opening width 8.0 mm and length 7.5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Fenestrated large type 1/1 (mm), opening width 8.0 mm and length 10 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Fenestrated large type 1/1 (mm), opening width 8.0 mm and length 5 mm....
Medicine Products: