Navigation Links
Intarcia Presents Positive ITCA 650 Phase 2 Study Results for Type 2 Diabetes at EASD
Date:9/22/2010

p>

23%week 6

8%

23%

19%week 12

2%

19%

19%Mean improvement in patient-reported QOL
week 8 vs. baseline

21%

34%

13%* p<0.001 relative to baseline"ITCA 650 therapy represents an important advance in the treatment of type 2 diabetes.  For the first time, patients are able to receive all the benefits of a GLP-1 therapy without the need for self-injection," said Robert Henry, M.D., Chief, Section of Diabetes, Endocrinology and Metabolism at the University of California, San Diego. He noted, "Injection has been a significant hurdle for the use of GLP-1 therapies for many patients.  ITCA 650 allows far more patients to benefit from GLP-1 therapy due to better tolerability and ease of administration. We are highly encouraged by improved levels of patient acceptance of ITCA 650, indicating broader use potential."

Summary of Week 24 ResultsAfter initial treatment week 12, patients on the ITCA 650 arms were re-randomized on a 1:1 basis to either continue on the same dose (20 mcg/day or 40 mcg/day) or escalate to higher doses of ITCA 650 (60 mcg/day or 80 mcg/day) for weeks 13 - 24.  Patients on the exenatide injection arm were switched to receive ITCA 650 at a dose of either 40 mcg/day or 60 mcg/day for weeks 13 – 24.

Incremental reductions in HbA1c and weight were observed across all treatment arms at week 24 compared to week 12. Both incremental and aggregate reductions in HbA1c were greatest in the 60 mcg/day and 80 mcg/day dose arms but not measurably different between the two dose arms.  Results of the week 20 quality of life assessment suggest that quality of life improved substantially for patients switching from exenatide injection to ITCA 650 and that the substantial improvement observed among patients initially randomized to ITCA 650 was maintained after transition to higher doses of ITCA 650.ITCA 650 Dose weeks 13 – 24

20 mcg/day


'/>"/>

SOURCE Intarcia Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Intarcia Therapeutics, Inc. Announces Completion of Enrollment of ITCA 650 Phase 1b Study for the Treatment of Type 2 Diabetes
2. Intarcia Therapeutics Names Kurt Graves Executive Chairman to Advance Strategic Interests and Broaden Commercial Goals
3. Genaera Corporation Presents Interim Phase 1 Data for Obesity Compound Trodusquemine (MSI-1436) at IBC Conference
4. EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer
5. Pharmasset Presents R7128 Phase 1 Single Ascending Dose Study in Healthy Volunteers
6. Anadys Pharmaceuticals Presents Preclinical Results on ANA598, a Non-Nucleoside Inhibitor of the NS5B Polymerase, at the 14th International Symposium on Hepatitis C Virus and Related Viruses
7. CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein
8. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
9. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
10. Wyeth Presents Phase 3 Fracture Data for Bazedoxifene, an Investigational Therapy for Osteoporosis
11. Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... According to the new ... therapy, Hydrotherapy), Accessories (Posture Mirror, Exercise Ball), Applications (Pediatric, ... Global Forecast to 2019" published by MarketsandMarkets, the global ... Million by 2019 from $14,240.0 Million in 2014, ... 2019. Browse 74 market data tables ...
(Date:9/19/2014)... WASHINGTON , Sept. 19, 2014 The ... that Drive Medical Design and Manufacturing has joined the ... its CEO Harvey Diamond have been actively ... year history, as it has quickly grown into a ... corporate partners like Drive allows AAHomecare to increase efforts ...
(Date:9/19/2014)... , September 19, 2014 ... by Equipment Type (Benchtop, Mobile, Industrial, & Laboratory), ... Technology (Tray-style, Manifold, & Rotary) & Geography - ... MarketsandMarkets, defines and segments the lyophilization market on ... with analyses and projections of the market size ...
Breaking Medicine Technology:Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 2Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 3Physiotherapy Equipment Market Worth $19,786.3 Million by 2019 4Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3
... 2011 BioMed Realty Trust, Inc. (NYSE: ... of its 2010 distributions as follows:Security Description: Common ... ShareAllocable to 2010Taxable Ordinary DividendReturn of CapitalLong-Term Capital ... , $0.140000 , $0.090527 , $0.049473 , $0.000000 ...
... Jan. 19, 2011 Pervasis Therapeutics, Inc. today announced ... therapy (PVS-30200) to target and regulate cell stroma (the ... supporting cell types distinct from cancer cells) in order ... advancing solid tumor growth and metastasis (the spread of ...
Cached Medicine Technology:BioMed Realty Trust Announces Tax Treatment of 2010 Distributions 2Pervasis Therapeutics to Develop Novel Cell-Based Approach to Target Tumor Environment, Prevent Cancer Recurrence 2Pervasis Therapeutics to Develop Novel Cell-Based Approach to Target Tumor Environment, Prevent Cancer Recurrence 3Pervasis Therapeutics to Develop Novel Cell-Based Approach to Target Tumor Environment, Prevent Cancer Recurrence 4Pervasis Therapeutics to Develop Novel Cell-Based Approach to Target Tumor Environment, Prevent Cancer Recurrence 5
(Date:9/20/2014)... New York, New York (PRWEB) September 20, 2014 ... of power morcellators ( http://www.injurybeacon.com/power-morcellator/ ) in ... notes that yet another insurer has announced plans ... a statement posted on its website last month, ... such procedures effective November 1, 2014. The insurer ...
(Date:9/20/2014)... 2014 The excitement is building up once again ... Carolina. This year the Surry Arts Council will be celebrating ... the country who are still fans of the Andy Griffith Show. ... that aired on CBS from 1960 through 1968. The show ... television history. Mount Airy, North Carolina is where the show ...
(Date:9/20/2014)... Recently, UWDress.com, an innovative company that provides ... outfits, has launched a special offer for its brand ... popular among worldwide clients. Now, all the company’s new ... on its website. , Additionally, the firm also ... world. Great custom made items can be ordered at ...
(Date:9/20/2014)... Wisconsin (PRWEB) September 20, 2014 QueenBeeTickets.com ... the young star’s tour performances. She will visit many ... of February until the 16th of April. , ... Grande Honeymoon Tour tickets at QueenBeeTickets.com. , The star’s ... opportunity to see their favorite young singer in a ...
(Date:9/20/2014)... (PRWEB) September 20, 2014 The Arizona ... College (MCC) is celebrating National Manufacturing Day by opening ... enhanced machining, processing and additive manufacturing labs will be ... 3, 2014 at MCC’s Southern and Dobson campus (1833 ... in southeast Lot D. , The AzAMI at MCC ...
Breaking Medicine News(10 mins):Health News:As Power Morcellator Concerns Grow, Bernstein Liebhard LLP Notes Another Insurer’s Decision to Drop Coverage for Uterine Morcellation 2Health News:As Power Morcellator Concerns Grow, Bernstein Liebhard LLP Notes Another Insurer’s Decision to Drop Coverage for Uterine Morcellation 3Health News:Mayberry Days Parade Cars will be Provided by Mount Airy Toyota and Mount Airy Chrysler Dodge Jeep Ram 2Health News:Discounted 2014 Prom Dresses Provided By Innovative Company UWDress.com 2Health News:Discount Ariana Grande Tickets: QueenBeeTickets.com Delights Fans with Discount Concert Tickets for Ariana Grande’s 2015 Honeymoon Tour 2Health News:National Manufacturing Day Open House at Mesa Community College Oct. 3 2
... new study published in the current issue of the Journal of ... are based on their ethnicity and racial backgrounds. // The study ... days at a nursing home, while African Americans did not mind ... worried about it. ,White people did ...
... caused by non veg items but now roam tomatoes have been ... that three outbreaks in 2004 were caused by this agent. ... caused havoc. ,The link was establoished when it ... item that was roma tomatoes. ,So the direct culprit ...
... of Infectious Diseases, and Bernard Moss, NIAID's Laboratory of Viral ... prevent and treat small pox virus infection. Though Small pox ... fear over the use of small pox virus as a ... referral strains are only available in two places in the ...
... and his colleagues have reported in the Cochrane Database ... genital tract reduces// the surgical procedure such as Episiotomy ... surgical procedure done in the perineum in the area ... involved during birthing process to expand the opening of ...
... fears of anxiety-ridden fathers are passed on to the ... As many as 65 women were studied by the ... at this conclusion. ,This increased the pain ... affect their immediate recovery and factors such as breastfeeding ...
... risk of dementia at a latter age can be halved ... research findings published in the Psychological Medicine//. Cognitive decline can ... occupational complexity. As many as 29,000 people from 22 studies ... of Psychiatry’s Dr Michael Valenzuela has revealed that where the ...
Cached Medicine News:Health News:Death Wishes Influenced By Ethnicity and Racial Background 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: