Navigation Links
Instrumentation Laboratory Introduces Automated HemosIL VWF Ristocetin Cofactor Activity Assay in Europe and International Regions
Date:11/29/2011

BEDFORD, Mass., Nov. 29, 2011 /PRNewswire/ -- Instrumentation Laboratory (IL) today announced the release of the new HemosIL von Willebrand Factor Ristocetin Cofactor Activity (VWF: RCo) assay as a European CE IVD Mark product under the European Directive on in vitro Diagnostic Medical Devices.  It will be commercialized in Europe and other international regions.  This new, fully automated VWF: RCo assay is for use on the ACL TOP® Family of Hemostasis Testing Systems. Together with other HemosIL reagents (HemosIL VWF Antigen, HemosIL VWF Activity, and HemosIL FVIII), it aids in the diagnosis and monitoring of von Willebrand Disease (VWD). 

(Logo:  http://photos.prnewswire.com/prnh/20100803/NE44435LOGO )

Based on new proprietary technology, the assay represents an innovative approach to VWD testing. Demonstrating excellent agreement with existing ristocetin-platelet-based tests, the HemosIL VWF: RCo assay eliminates platelet-associated variability.  The result is superior precision.  Additionally, variability associated with human interpretation, common with manual testing methods, is eliminated.  Moreover, because the assay is automated, liquid and ready-to-use, results are available in minutes and on-demand, 24/7. 

"This important new addition to our portfolio of VWF assays will help ensure early diagnosis and proper treatment for patients," said Remo Tazzi, Director, Hemostasis Marketing at IL.  "By simplifying and automating a complex procedure, the HemosIL VWF: RCo assay marks a significant improvement in not only the turnaround time for results, but also in accuracy and precision.  It is a perfect example of our commitment to providing specialized solutions for disease-state management."

About von Willebrand Disease

VWD is the most common inherited blood disorder, occurring in approximately 1% of the general population.  It disrupts the blood's ability to clot properly.  Unlike hemophilia, it affects both genders and is caused by a quantitative defect (i.e., VWF level is abnormally low) or a qualitative defect (i.e., VWF has abnormal physical characteristics) of the VWF.   A large protein involved in primary hemostasis, VWF helps platelets stick to damaged vessel walls and carries the clotting protein, Factor VIII, in the blood.  Excessive or prolonged bleeding can be a sign of VWD.  For those with a moderate-to -severe form of the disease, proper diagnosis and treatment is essential.  Acquired von Willebrand Syndrome (AVWS) can also occur as a direct consequence of other medical disorders.  Laboratory findings in AVWS are similar to those in VWD and may include decreased values for VWF:Ag, VWF:RCo, or FVIII.

Principle of the HemosIL VWF:RCo Assay

HemosIL VWF:RCo assay detects quantitative and qualitative VWF defects (VWD Type 1, 2 and 3).  It is based on the principle that a recombinant fragment of the platelet receptor, glycoprotein-Ib alpha contains the VWF-binding site.  The VWF:RCo reagent consists of a latex particle, coated with glycoprotein-Ib alpha, through a highly specific monoclonal antibody.  If VWF is present in the sample, it will bind to the glycoprotein-Ib alpha fragment, in the presence of ristocetin.  The degree of agglutination is directly proportional to the activity of VWF in the sample, and is determined by measuring the decrease of transmitted light caused by the aggregates.

HemosIL VWF:RCo Assay is not currently 510(k) cleared.

Instrumentation Laboratory (www.ilus.com), founded in 1959, is a worldwide developer, manufacturer and distributor of in vitro diagnostic instruments, related reagents and controls for use primarily in hospitals and independent clinical laboratories.  The company's product lines include critical care systems, hemostasis systems and information management systems.  IL's GEM® product offerings, part of the critical care line, include the GEM Premier™ 4000 analyzer with Intelligent Quality Management (iQM®), GEM Premier 3500, GEMweb® Plus Custom Connectivity, and the GEM PCL Plus, a portable coagulation analyzer.  IL's hemostasis portfolio includes the ACL TOP® Family of Hemostasis Testing Systems, fully automated, high-productivity analyzers, including the ACL TOP 700, ACL TOP 700 LAS and ACL TOP 500 CTS.  IL also offers the new ACL AcuStar®, ACL ELITE® and ELITE PRO, other hemostasis analyzers and the HemosIL® line of reagents.  IL is based in Bedford, Massachusetts.

The Instrumentation Laboratory logo, GEM, iQM, HemosIL, ACL TOP, ACL ELITE, ACL AcuStar and Premier are trademarks of Instrumentation Laboratory Company and/or one of its subsidiaries or parent companies, and may be registered in the United States Patent and Trademark Office and in other jurisdictions.  All other product names, company names, marks, logos, and symbols are trademarks of their respective owners.


'/>"/>
SOURCE Instrumentation Laboratory
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Instrumentation Laboratory Receives FDA Clearance for HemosIL RecombiPlasTin 2G Assay
2. Instrumentation Laboratory Installs 2000th ACL TOP(R) System
3. Amerinet Awards Contract to Instrumentation Laboratory for Critical Care Portfolio
4. Instrumentation Laboratory Receives 510(K) Clearance From FDA and Canadian License for HemosIL(R) D-Dimer HS 500 Assay
5. Patient-Specific Surgical Instrumentation Expedites Total Knee Replacement Procedures
6. Instrumentation Laboratory Achieves Record Sales in 2009
7. Instrumentation Laboratory Receives FDA Clearance for New Automated Total Bilirubin Assay on GEM Premier 4000 Critical Care Analyzer
8. Instrumentation Laboratory Introduces Fully Automated, Liquid, Ready-to-Use HemosIL® HIT-Ab(PF4-H) Assay in Europe
9. Specialty Surgical Instrumentation Launches New Interactive Web Site
10. Instrumentation Laboratory to Host 2nd Asia Pacific Hemostasis Forum
11. Reportlinker Adds Global Ophthalmic Instrumentation Industry
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... June 24, 2016  Arkis BioSciences, a leading ... and more durable cerebrospinal fluid treatments, today announced ... Series-A funding is led by Innova Memphis, followed ... other private investors.  Arkis, new financing will accelerate ... the market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... BEVERLY HILLS, Calif. , June 23, 2016 ... faced the many challenges of the current process. Many of ... option because of the technical difficulties and high laboratory costs ... would have to offer it at such a high cost ... to afford it. Dr. Parsa Zadeh , ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced that it ... (procalcitonin) assay as a dedicated testing solution for people ... Roche is the first IVD company in the U.S ... assessment and management. PCT is a sepsis-specific ... blood can aid clinicians in assessing the risk of ...
Breaking Medicine Technology:
(Date:6/27/2016)... ... June 27, 2016 , ... TherapySites, ... its affiliation with Tennessee Counseling Association. This new relationship allows TherapySites ... Tennessee Counseling Association, adding exclusive benefits and promotional offers. , "TCA is extremely ...
(Date:6/26/2016)... ... ... Quality metrics are proliferating in cancer care, and are derived from many of ... beholder, according to experts who offered insights and commentary in the current issue of ... full issue, click here . , For the American Society of Clinical Oncology ...
(Date:6/26/2016)... ... ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a weight ... app plans to fix the two major problems leading the fitness industry today:, ... program , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... ... Bruton Memorial Library on June 21 due to a possible lice infestation, as reported by ... lice: the parasite’s ability to live away from a human host, and to infest common ... the event that lice have simply gotten out of control. , As lice are a ...
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
Breaking Medicine News(10 mins):