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Inspiro Medical Ltd. Completes a Successful First Clinical Trial in Asthmatic Children

TEL AVIV, Israel, June 6, 2013 /PRNewswire/ --

Inspiro Medical, a portfolio company of The Trendlines Group, recently completed a successful clinical trial for InspiromaticTM, its innovative, breath-synchronized, active dry powder inhaler.

The study, completed in May 2013 at Schneider Medical Center aimed to objectively assess, in a randomized, crossover, double blind study, the efficacy and safety profiles of formoterol (bronchodilator) treatment via the Inspiromatic in asthmatic children, compared to its delivery via a competitive inhaler already on the market.

30 children with asthma, aged 8-18, were randomly allocated to treatment with formoterol via the Inspiromatic inhaler or a competitive device.

The study met both primary and secondary endpoints. The results demonstrated superior results for of the Inspiromatic in pulmonary delivery of the active drug. Lung function test (FEV1) demonstrated a statistically significant improvement following formoterol delivery via the Inspiromatic. Moreover, the Inspiromatic was highly rated by patients. Successful delivery of the API was achieved even with patients with poor inhalation technique and even in low-flow inhalation rate.  

"I'm very happy with the study results showing that the Inspiromatic achieved safety and efficacy," said Nimrod Kaufmann , CEO of Inspiro Medical. "This successful study will enable us to move to the next step in the company development and partner with pharmaceutical companies to develop drug-device combinations and also bring better therapy to patients with poor inhalation technique."  

Despite the numerous aerosol delivery devices currently on the market, Inspiro Medical believes that their device can significantly improve effectiveness in deposing the necessary medication. Inspiromatic takes into account drug particle/droplet size; design of the delivery device; and the patient's ability to use and understand the device.

Following this successful trial, Inspiro Medical will continue partnering with global pharmaceutical companies to jointly develop combination products.

Inspiro Medical will be opening investment round A in Q3/2013 to further develop its device and support partnering activities.

Nimrod Kaufmann will present Inspiro's proven technology at BioMed 2013 in Tel Aviv on June 10.

Company contact details:

Nimrod Kaufmann , CEO
Tel: +972-72-260-7051

Media relations:

Efrat Kaduri
Ofir Shpigel Media and Public Relations

SOURCE Inspiro Medical Ltd.
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