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Inovio Pharmaceuticals Universal H1N1 Influenza Vaccine Achieves Protective Immune Responses Comparable to Conventional Vaccine in Phase I Study
Date:4/18/2013

vorable safety profile is consistent with multiple studies in different disease areas in which Inovio DNA vaccines delivered with Inovio electroporation delivery devices have been administered to over several hundred subjects.

About Inovio's Universal Influenza DNA Vaccine Program

Inovio aims to leverage the greater breadth of immune responses achievable using its SynCon® vaccine design to revolutionize the flu vaccine market.

We are advancing the development of a universal seasonal flu vaccine to protect against H1N1, H3N2, and Type B influenza strains, the subtypes comprising today's FDA-approved seasonal vaccines. In addition to the ongoing H1N1 study in elderly subjects (65+ years), for which we reported positive interim data in December, the company is completing immunogenicity testing across multiple strains in animal models of its vaccine constructs for A/H3N2 and Type B influenza.

We are also advancing development initiatives focused on the pandemic influenza subtypes H5N1 and H7N9. Our goal is to access the pandemic stockpiling market, which is dominated by government buyers.

About Inovio Pharmaceuticals, Inc.

Inovio is revolutionizing vaccines to prevent and treat today's cancers and challenging infectious diseases. Its SynCon® vaccines are designed to provide universal protection against known as well as new unmatched strains of pathogens such as influenza. These synthetic vaccines, in combination with Inovio's proprietary electroporation delivery, have been shown in humans to generate best-in-class immune responses with a favorable safety profile. Inovio's clinical programs include phase II studies for cervical dysplasia, leukemia and hepatitis C virus and phase I studies for influenza and HIV. Partners and collaborators include the University of Pennsylva
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SOURCE Inovio Pharmaceuticals, Inc.
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