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Inovio Pharmaceuticals Reports 2012 Fourth Quarter and Year End Financial Results
Date:3/18/2013

es/toc/volume/8/issue/11/">Human Vaccines & Immunotherapeutics.

Inovio scientists and collaborators demonstrated in animal models that optimized electroporation (EP) parameters of our new minimally invasive skin (intradermal) EP delivery devices using decreased current could generate stronger antibody and T cell responses to HIV and flu vaccine antigens in both guinea pigs and monkeys. These newly published optimized conditions, which enhance this delivery system as an attractive method for mass vaccination, appeared in the peer-reviewed journal, Human Gene Therapy

Corporate DevelopmentInovio continues to advance discussions with large pharmaceutical companies with the goal of securing strategic partnerships to advance the development of SynCon® vaccines.

In 2012 Inovio expanded its existing license agreement with the University of Pennsylvania with worldwide rights to technology and intellectual property for novel synthetic vaccines against C. difficile (intestinal infections),  Wilms' tumor gene (leukemia and various solid tumor types), and Ebola virus and the family of Filovirus such as Marburg (which could potentially be used in bioterror attacks).

Inovio received U.S. patents covering its synthetic consensus influenza H1 and cervical dysplasia/cancer SynCon® DNA vaccine constructs, adding to its patent estate of more than 400 worldwide granted and pending patents.

We were awarded a U.S. Department of Defense Small Business Innovation Research Grant to advance a low-cost, non-invasive surface electroporation delivery device and test its utility in combination with Inovio synthetic vaccines against viruses with bioterrorism potential.

Our VGX Animal Health subsidiary reported advancements for its growth hormone releasing hormone (GHRH) treatment focused on enhancing health and food production efficiency of farm animals. Previously approved in Australia, the Company w
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SOURCE Inovio Pharmaceuticals, Inc.
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