Navigation Links
Initiation of Antiretroviral Treatment Protects Uninfected Sexual Partners from HIV Infection (HPTN Study 052)
Date:5/12/2011

WASHINGTON, May 12, 2011 /PRNewswire-USNewswire/ -- Men and women infected with HIV reduced the risk of transmitting the virus to their sexual partners through initiation of oral antiretroviral therapy (ART), according to findings from a large multinational clinical study conducted by the HIV Prevention Trials Network (HPTN), a global partnership dedicated to reducing the transmission of HIV through cutting-edge biomedical, behavioral, and structural interventions.

The study, known as HPTN 052, was designed to evaluate whether immediate versus delayed use of ART by HIV-infected individuals would reduce transmission of HIV to their HIV-uninfected partners and potentially benefit the HIV-infected individual as well. Findings from the study were reviewed by an independent Data and Safety Monitoring Board (DSMB).The DSMB recommended that the results be released as soon as possible and that the findings be shared with study participants and investigators. The DSMB concluded that initiation of ART by HIV-infected individuals substantially protected their HIV-uninfected sexual partners from acquiring HIV infection, with a 96 percent reduction in risk of HIV transmission. HPTN 052 is the first randomized clinical trial to show that treating an HIV-infected individual with ART can reduce the risk of sexual transmission of HIV to an uninfected partner.

"This is excellent news," said Dr. Myron Cohen, HPTN 052 Principal Investigator and Associate Vice Chancellor for Global Health and Director of the Institute of Global Health and Infectious Diseases at the University of North Carolina at Chapel Hill. "The study was designed to evaluate the benefit to the sexual partner as well as the benefit to the HIV-infected person. This is the first randomized clinical trial to definitively indicate that an HIV-infected individual can reduce sexual transmission of HIV to an uninfected partner by beginning antiretroviral therapy sooner. HPTN recognizes the significant contr
'/>"/>

SOURCE HIV Prevention Trials Network
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Initiation of FLINT Announced by NIDDK: Study of Intercept Pharmaceuticals Obeticholic Acid (INT-747) in NASH
2. Genus Oncology, LLC Announces Initiation of Phase I Trial of GO-203-2c in Patients With Solid Tumors
3. Vicus Therapeutics Announces Initiation of Phase 2 Trial to Evaluate VT-122 in Patients with Liver Cancer Receiving Nexavar
4. Jennerex and Transgene Announce Initiation of Clinical Trial of Intravenous JX-594 in Patients With Refractory Metastatic Colorectal Cancer
5. Upsher-Smith Laboratories Announces Initiation of Open-Label Extension Study of USL255 (Extended-Release Topiramate) for Adjunctive Treatment of Partial-Onset Epilepsy
6. Amira Pharmaceuticals Announces Initiation of Phase I Clinical Trial for AM152, A Novel LPA1 Antagonist
7. BioSpecifics Technologies Corp. Announces Initiation of Global Phase 3 Trial of XIAFLEX® for Treatment of Peyronies Disease
8. Auxilium Pharmaceuticals, Inc. Announces Initiation of XIAFLEX® Phase III Studies for Peyronies Disease
9. Agensys, an Affiliate of Astellas, Announces Initiation of Phase I Clinical Trial of AGS-16M8F for Renal Cancer
10. Ampio Pharmaceuticals Announces Initiation of Phase II Clinical Trial of Optina™
11. Upsher-Smith Laboratories Announces Initiation of Phase III Clinical Trial of USL255 (Extended-Release Topiramate) for Adjunctive Treatment of Partial-Onset Epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... , Aug. 29, 2014 The clinical and ... be the difference between a product,s success or failure. ... and stratify KOL targets – and then to coordinate ... of strong relationships upon which successful KOL engagement rests. ... companies have identified internal inconsistencies in their KOL management ...
(Date:8/29/2014)... WILSONVILLE, Ore. , Aug. 29, 2014 /PRNewswire-iReach/ ... its Accessory (Axilla) Strap for the SAM Junctional ... SAM Medical Products announced ... a voluntary recall to address a potential issue ... strap used for the Axilla application of the ...
(Date:8/29/2014)...  A Boston Scientific Corporation (NYSE: ... and preliminary long term stricture resolution of benign ... issue of the peer-reviewed journal, Gastroenterology. ... conducted in 11 countries and five continents, and ... (FCSEMS) after extended indwell (i.e., up to 12 ...
Breaking Medicine Technology:Implementing a Strategic Thought Leader Management & Engagement System 2SAM Medical Products Implements Voluntary Recall of its Accessory (Axilla) Strap for the SAM Junctional Tourniquet. 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 2Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 3Boston Scientific Study Published In Gastroenterology Reports Successful Management Of Benign Biliary Strictures With Fully Covered Metal Stents 4
... JERUSALEM , June 2, 2010 Oramed ... announced,today that its subsidiary Oramed Ltd. entered into a joint ... company listed on,the Tel Aviv Stock Exchange, for the establishment ... Under the terms of the agreement, Oramed,will out-license technology to ...
... June 1 The U.S. Food and Drug Administration today approved Prolia, ... for fractures. , , , ... ) , , , ... which the bones become weak and are more likely to break. According to ...
Cached Medicine Technology:Oramed Pharmaceuticals Forms Joint Venture - Launches Entera Bio Ltd. 2Oramed Pharmaceuticals Forms Joint Venture - Launches Entera Bio Ltd. 3FDA Approves New Injectable Osteoporosis Treatment for Postmenopausal Women 2FDA Approves New Injectable Osteoporosis Treatment for Postmenopausal Women 3
(Date:8/29/2014)... Village, IL (PRWEB) August 29, 2014 ... Baty, “The Safety Chick” who profiled a handful ... Safe-Listening Earphones from Etymotic Research. This year, many ... list, and Etymotic, an innovator of hearing wellness ... ears. Their ETY•Kids Safe-Listening Earphones, offered in yellow, ...
(Date:8/29/2014)... Mass. (August 29, 2014, 2 PM US Eastern ... is to inject antibodies, commonly produced in animals, ... challenges ranging from safety to difficulties in developing, ... , New research led by Charles Shoemaker, ... and Global Health at the Cummings School of ...
(Date:8/29/2014)... 2014 The microbiology testing sector is ... diagnostics industry; it is also the hugest challenge facing ... the ongoing spread of AIDS – still the world’s ... the upsurge of opportunistic infections (OIs); bioterrorism threat; advancements ... of immunosuppressive medicines. Although for certain infections the etiology ...
(Date:8/29/2014)... News) -- Prostate cancer patients lacking knowledge about the ... lead to worse quality of care and long-term results, ... with a median age of 63. All were newly ... the disease was associated with greater difficulty deciding which ... would be effective, the study found. "For prostate ...
(Date:8/29/2014)... 2014 Edvance360, a leading provider of ... online teaching, as well as 2011 winner and six-time-finalist ... Management System, announced that Brooke Education Services, Northwest Academy, ... Interactive Advertising Bureau of Canada (IAB Canada), StarSVCS, and ... are delighted to welcome each new client to the ...
Breaking Medicine News(10 mins):Health News:The Today Show Features ETY•Kids® Safe-Listening Earphones by Etymotic 2Health News:Mice study shows efficacy of new gene therapy approach for toxin exposures 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 2Health News:Infectious Disease Testing Universe Examined in New VPG Research Report Available at MarketPublishers.com 3Health News:Faced With Prostate Cancer, It Helps to Know the Enemy 2Health News:Edvance360 Continues to Experience Growth in Corporate, K-12, Health, and Non-Profit Sectors 2
... - Nearly 500 kindergarten schools on the island ... , from the eastern Malaysian state of Sarawak// succumbed to ... reports from the official news agency today. ,Health ... ordered immediate closure of 488 schools for two weeks, with ...
... Wales have discovered that temporary injury to the ... lead to chronic fatigue syndrome (CFS). ,More ... the brain that play a critical role in the ... infection could damage the above-mentioned regions of the brain. ...
... centres have been blamed for interfering in the approach ... the where and when// of patient surgery, serve as ... the British Medical Association feel that the inference lead ... referral management centres are currently being managed by staff ...
... virtual reality simulation tools are making dentists hone their ... Cenk Cavusoglu has his // way, then this method ... delicate surgeries in a risk-free manner. ,"Simulation ... learning time and allows students to learn independently," said ...
... scientists in Victoria have claimed that they have developed ... ,These two viruses in question can easily kill humans ... charge sheet against the viruses is that Hendra virus ... Rail and 16 horses in Brisbane. Thereafter the trainer ...
... German study has now proved that acupuncture, even sham acupuncture ... treating migraine//. A comparable level of treatment efficacy has been ... obtained with respect to reduction in migraine days. ... included for the study. The study participants who had two ...
Cached Medicine News:Health News:Brain Injury, A Consequence Of Glandular Fever Could Trigger Fatigue Syndrome 2Health News:Referral Schemes Blamed By GPs For Treatment Delay 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: