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Independent Data Published on BioLife Solutions HypoThermosol® and CryoStor®
Date:1/27/2012

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  • About 95% of frozen cells were recovered as live cells after freezing in CryoStor solutions with 5% and 10% DMSO followed by storage in liquid nitrogen for 1 month 
  • Hypothermic storage for 2 and 4 days resulted in about 100% and 85% cell recovery respectively, less than 10% of apoptotic cells, and normal proliferation, marker expression, and osteogenic potential
  • Results demonstrate that human MSC could be successfully cryopreserved for banking and clinical applications and delivered to the bedside in clinically safe protective reagents
  • Hypothermic storage of isolated human hepatocytes: a comparison between University of Wisconsin solution and a hypothermosol platform, in Archives of Toxicology.
  • Cell viability, energy status, and xenobiotic metabolism following cold preservation in HypoThermosol was consistently and, in some cases, markedly higher when compared with other systems
  • Moreover, the use of HypoThermosol eliminates the need for serum in preservation solutions
  • HypoThermosol represents an improved solution compared to UW for extending the shipping/storage time of human hepatocytes
  • Additional published data by customers, which cite the use of BioLife include:

  • A double-blind, randomized, controlled, multicenter study to assess the safety and cardiovascular effects of skeletal myoblast implantation by catheter delivery in patients with chronic heart failure after myocardial infarction, by the Duke Clinical Research Institute and several other centers, in the American Heart Journal.
  • Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous and placebo in patients with critical limb ischemia, in the

  • SOURCE BioLife Solutions, Inc.
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