Navigation Links
InNexus Lead Candidate DXL625 Outperforms Rituxan in Additional Animal Studies
Date:9/16/2008

- Biotech Begins to Demonstrate Strategy to Expand NHL Marketplace with Novel Antibody and Speedy DXL Screening Preclinical Development Program -

BRITISH COLUMBIA, Canada, Sept. 16 /PRNewswire-FirstCall/ -- InNexus Biotechnology Inc. (TSX VENTURE: IXS; OTC Bulletin Board: IXSBF; http://www.ixsbio.com), a drug development company commercializing the next generation of monoclonal antibodies based on its technology, Dynamic Cross Linking (DXL(TM)), announced today the results of an extensive mouse tumor study demonstrating superiority of InNexus' DXL625 (CD20) versus Rituxan(R) in the xenograft model.

InNexus plans to submit the data for publication along with additional data from animal studies recently completed and presented at the American Association for Cancer Research (AACR) 2008 Annual Conference. The company has also launched a large scale study of DXL625 with primates, designed to evaluate toxicity and pharmokinetics, enabling the company to move the product to the FDA toward human testing.

"A study performed by an independent group investigating the survival of mice intravenously injected with B-lymphoma cells and treated subsequently with DXL625 showed a significant improvement in outcome compared to animals treated with equivalent doses of Rituxan(R), a commercially available anti-CD20 antibody," said Dr. Thomas Kindt, InNexus' Chief Scientific Officer. "Animals treated with either drug had a superior outcome when compared to those receiving inactive control (vehicle), however DXL625 had a substantial advantage over the competing antibody. We are confident that these results will translate to therapeutic advantage when DXL625 is used in human subjects."

"The DXL(TM) technology platform builds better antibodies and soon you'll be able to see our strategy to expand the NHL marketplace. We enhance an antibody's potency in a real, measurable and predictable fashion," said Jeff
'/>"/>

SOURCE InNexus Biotechnology Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Lexicon to Present Research Results at American Chemical Society Meeting Regarding Target of LX1031 Drug Candidate
2. GlaxoSmithKline Receives New HHS Order for H5N1 Bulk Antigen. First North American Clinical Trials with GSKs Candidate Pre-pandemic Flu Vaccine to Start.
3. Lpath Demonstrates Strong Safety Profile of Lead Drug Candidate, Sphingomab(TM), in Non-Human Primates
4. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
5. Upstream Biosciences Acquires Innovative Platform Technology and Drug Candidates for Tropical Parasitic Diseases
6. Phase 2 Clinical Studies Initiated for a Novel Therapeutic Candidate Identified Through Pharmacopeia Collaboration
7. BiPar Expands Management Team to Advance Lead PARP Inhibitor Product Candidate Into Phase 2 Trials for Cancer
8. Pharmacopeia Earns Milestone Payment From Schering-Plough on Initiation of Phase 1 Clinical Trials of Novel Therapeutic Candidate
9. Horizon Therapeutics Initiates Long-Term Phase 3 Safety Study for Lead Product Candidate HZT-501
10. Survival Data for Avicenas Amyotrophic Lateral Sclerosis Drug Candidate, AL-02, to be Presented at 18th International Symposium on ALS/MND
11. Leading AIDS Groups Turn Up The Heat on 08 Presidential Candidates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... 2014 Ambit Biosciences (Nasdaq: AMBI ), a ... unmet needs in oncology, autoimmune and inflammatory disease, today announced ... to be held at The New York Palace Hotel in ... 2014. Alan Fuhrman , Ambit,s CFO, will ... candidate, quizartinib, at 1:10 p.m. ET on Wednesday, September 3, ...
(Date:8/27/2014)... Calif. , Aug. 27, 2014 IRIDEX Corporation ... CFO James H. Mackaness is scheduled to make ... Care Conference at 2:55 p.m. Eastern Time on Wednesday, September ... audio webcast of the investor presentation will be available in ... . About IRIDEX IRIDEX Corporation ...
(Date:8/27/2014)... , Aug. 27, 2014 Sinovac Biotech Ltd. (NASDAQ: ... China , today announced the results of the Company,s ... 2014 in Beijing , PRC. The required quorum, ... The Company,s shareholders approved the following proposals:  ... Lam Lo , Simon Anderson , Kenneth Lee ...
Breaking Medicine Technology:Ambit Announces Participation At Baird 2014 Health Care Conference 2Sinovac Announces Results of 2014 Annual General Meeting of Shareholders 2
... Calif., March 14, 2011 Varian Medical Systems (NYSE: ... for second quarter of fiscal year 2011 following the close ... release will be followed by a teleconference available to all ... a link to the conference call webcast will be available ...
... -- China Botanic Pharmaceutical Inc. (AMEX: CBP ... and distributor of botanical products, bio-pharmaceuticals and traditional Chinese ... conference call at 9:00 a.m. Eastern Daylight Time on ... the first quarter of fiscal year 2011 ended January ...
Cached Medicine Technology:Varian Medical Systems Schedules Second Quarter FY2011 News Release and Conference Call 2China Botanic Schedules Conference Call to Discuss FY 2011 First Quarter Results 2
(Date:8/27/2014)... PA (PRWEB) August 27, 2014 What’s ... of this year’s 87th Annual Scripps National Spelling Bee? ... for a tour of internationally renowned Wills Eye Hospital.     ... like to be an ophthalmologist one day. , Wills ... eye surgery and the latest hi-tech visual diagnostic testing. ...
(Date:8/27/2014)... WEDNESDAY, Aug. 27, 2014 (HealthDay News) -- A new ... an effective treatment for seniors with sleep apnea. ... obstructive sleep apnea, a condition in which the airway ... interrupted sleep that leads to daytime drowsiness. ... stream of air through a patient,s nose via a ...
(Date:8/27/2014)... each receive $100,000 in funding to launch pilot programs ... for patients served by community health centers. The program ... and is part of the group,s effort to reach ... over receiving regular screening for colorectal cancer by 2018. ... are: Port Royal, South Carolina; New Haven, Connecticut; and ...
(Date:8/27/2014)... Driven by the expanded automobile market capacity, ... steadily during the next few years, with the demand ... by end-2017. Tightness is an essential indicator for measuring ... most-used parts in an automobile. As of 2013, the ... meters, up just under 15% y-o-y. , The Chinese ...
(Date:8/27/2014)... Georgia State University’s Center for Leadership ... grant from the Maternal and Child Health Bureau ... support implementation of the Autism Plan for Georgia, ... with autism spectrum disorder. , In preparing for ... Council composed of key stakeholders from across Georgia. ...
Breaking Medicine News(10 mins):Health News:Scripps National Spelling Bee Co-Champion and Aspiring Ophthalmologist Coming to Wills Eye Hospital in Philadelphia 2Health News:Sleep Apnea Treatment Helps Seniors, Study Finds 2Health News:Pilot program aims to improve cancer screening, specialty care in community health centers 2Health News:Pilot program aims to improve cancer screening, specialty care in community health centers 3Health News:Automobile Weatherstrip Sector in China Analysed in New SinoMarketInsight Research Study Published at MarketPublishers.com 2Health News:Automobile Weatherstrip Sector in China Analysed in New SinoMarketInsight Research Study Published at MarketPublishers.com 3Health News:Center for Leadership in Disability Awarded $600,000 Grant to Improve Services for Georgia’s Children and Youth with Autism 2
... on Capitol Hill Once Negative Impact on,Local Seniors Becomes ... In thanking U.S.,Senators Kent Conrad (D-ND), Norm Coleman (R-MN) ... Moore Capito (R-WV) for leading a,new bipartisan effort in ... regulatory means $770 million in seniors, Medicare Part A ...
... 5 Hill-Rom (NYSE: HRC ),has received ... the,TotalCare(R) Bariatric Plus therapy system. The award recognizes ... the second year in a row,that a Hill-Rom(R) ... The TotalCare Bariatric Plus therapy system is an ...
... update, including fourth-quarter fiscal 2008 ... ... Meredith Corporation,(NYSE: MDP ), one of America,s leading media ... healthcare,marketing communications firm. Additionally, the company provided a,business update, and announced ...
... makes people more likely to reject unfair offer, study shows ... brain chemical known as serotonin govern the way people react ... a new study indicates. , Serotonin, which carries messages between ... that the expression of anger in women was affected by ...
... Duke University chemist has apparently solved a long-standing frustration in ... lead to better drugs with fewer side effects. , Like ... two shapes, right and left. But usually only one of ... at best useless and sometimes even harmful. For example, side ...
... months after completing high school are significantly less likely ... do not go to college, according to the first ... of Washington study, published in this month,s issue of ... behavior of teens living at home and those who ...
Cached Medicine News:Health News:Front Line Caregiver Coalition Thanks Sens. Conrad, Coleman and Reps. Pomeroy, Capito and Berkley for Leading Bipartisan Hill Effort to Stop Bush Administration's Damaging Medicare Cuts 2Health News:Hill-Rom Innovative TotalCare(R) Bariatric Plus Therapy System Receives Gold Medical Device Excellence Award 2Health News:Hill-Rom Innovative TotalCare(R) Bariatric Plus Therapy System Receives Gold Medical Device Excellence Award 3Health News:Meredith Expands Integrated Marketing Capabilities by Acquiring Top Healthcare Marketing Communications Firm 2Health News:Meredith Expands Integrated Marketing Capabilities by Acquiring Top Healthcare Marketing Communications Firm 3Health News:Meredith Expands Integrated Marketing Capabilities by Acquiring Top Healthcare Marketing Communications Firm 4Health News:Meredith Expands Integrated Marketing Capabilities by Acquiring Top Healthcare Marketing Communications Firm 5Health News:Serotonin Levels Determine Sense of Fairness 2Health News:Duke chemist has new way to tell right from left 2Health News:Teenagers attending college less likely to engage in risky sexual behavior 2Health News:Teenagers attending college less likely to engage in risky sexual behavior 3
... The CritSpin whisper quiet, compact system ... clinic anywhere fast, accurate and cost effective ... Digital Reader, the CritSpin System offers a ... spin, complete cell packing - Meets NCCLS ...
... light over one smooth pulse duration, rather ... damage skin) that other technologies use. Palomar's ... water supply through the StarLux handpiece, down ... to as low as 4 degrees C. ...
Used to provide drainage of urine from the bladder. All-silicone construction provides maximum softness and biocompatibility for enhanced patient comfort. Supplied sterile in peel-open packages. Inte...
Used for stenting the urethra during hypospadias or epispadias repair and to promote postoperative drainage of the bladder. Supplied sterile in peel-open packages. Intended for one-time use....
Medicine Products: