Navigation Links
In Rare Disorder, a Familiar Protein Disrupts Gene Function
Date:5/27/2009

nge syndrome." He added that a gene array might also be developed as a single-platform tool to diagnose, from a patient's blood sample, not only CdLS, but also a variety of other developmental disorders.

Funding for the study came from the National Institute of Child Health and Development of the National Institutes of Health, the Pennsylvania Department of Health, the Genome Network Project and Grant-in-Aid for Scientific Research from the MEXT, a Japanese government ministry. First author Jinglan Liu received a Cornelia de Lange Foundation Fellowship Grant.

Krantz's co-authors on the study came from Children's Hospital; the University of Pennsylvania School of Medicine; Drexel University School of Medicine; the Tokyo Institute of Technology; the Misakaenosono Mutsumi Developmental, Medical, and Welfare Center, in Isahaya, Japan; and the National University of Colombia, in Bogota, Colombia.

Liu et al, "Transcriptional dysregulation in NIPBL and cohesin mutant human cells," PloS Biology, published online, May 26, 2009.

About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking second in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.ch
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion
2. CEL-SCI Presents Data for CEL-1000 as a Vaccine Adjuvant with Recombinant Hepatitis B Virus Protein
3. Study Published in Endocrinology Reports Potential of Modigene Technology to Extend Duration of Protein Drugs
4. Study Suggests Soy Protein May Reduce Prostate Cancer Risk
5. Vical Demonstrates Dose-sparing of Protein-based H5N1 Influenza Vaccine With Vaxfectin(TM) Adjuvant
6. Exelixis Reports Top-Line Results of the Phase 2 Trial of XL784 in Patients With Proteinuria Associated With Diabetic Nephropathy
7. First High-Res 3-D Structures of Mammalian HSP90 Protein Solved, Key to Better Targets for AIDS, Sepsis, Cancer Drugs
8. The New England Journal of Medicine Publishes First Clinical Results for MedImmunes Chitinase-like Protein YKL-40 in Patients With Asthma
9. VioQuest Pharmaceuticals Announces Dosing of First Patient in Phase IIa Solid Tumor Study for Lenocta(TM), a Novel Protein Tyrosine Phosphatase Inhibitor
10. Neptune Industries Reports Favorable Phase II Trial Results on Ento- Protein(TM)
11. Fundamental Applied Biology, Inc. Is Awarded SBIR Phase IIB Grant for the Commercialization of Protein Therapeutics Using Cell Free Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2009)... December 17 ,Agendia, a world leader in ... and Drug Administration (FDA) cleared its MammaPrint breast,cancer ... only FDA-cleared,breast cancer recurrence test available to patients ... has issued four clearances for MammaPrint, covering,all aspects ... "This FDA clearance, along with our recently ...
(Date:12/17/2009)... SAN DIEGO, Dec. 17 Suneva Medical, ... that it has signed a multi-million dollar line ... The line of credit facility will be ... only FDA-approved microsphere-enhanced collagen dermal filler on the ... Aesthetic Market growth objectives. ,, "Today Suneva Medical ...
(Date:12/17/2009)... 17 Instacare Corp. (OTC Bulletin Board: ... life-enhancing prescription drugs and diagnostics and at home ... leading developer and provider of e-health technologies and ... today that as part of the preparation of ... to add two new Directors and has rejected, ...
Breaking Medicine Technology:FDA Broadens Clearance for Agendia's MammaPrint(R) 2Suneva Medical Signs Multi-Million Dollar Line of Credit Agreement with Western Technology Investment 2Suneva Medical Signs Multi-Million Dollar Line of Credit Agreement with Western Technology Investment 3Instacare Corp. Board of Directors Sets Growth Plans for 2010 2Normal cells far from cancer give nanosignals of trouble 9146 1Normal cells far from cancer give nanosignals of trouble 9146 2Normal cells far from cancer give nanosignals of trouble 9146 3Playing it safe 9143 1Claimsnet Announces Claims Processing Agreement With New Health Care Solutions Company 50956 1Claimsnet Announces Claims Processing Agreement With New Health Care Solutions Company 50956 2
(Date:12/17/2009)... arms and legs in order to correct limb deformities, repair traumatic ... patients can remain mobile while growing new bone, resulting in fewer ... ... December 17, 2009 -- Dr. Randolph C. Robinson , a ... in Lone Tree, Colorado, has been granted a U.S. patent ...
(Date:12/17/2009)... facial aesthetics specialist offers a discount certificate to introduce the wonders ... ... December 17, 2009 -- Jeffrey R. Raval, MD, FACS, a Denver ... Mountain Laser Aesthetics in Cherry Creek North, is offering an online ... Gift Certificate for $100 in services or products for just $75., ...
(Date:12/17/2009)... 17 Pacific Shore Holdings, ... balms, today announced the launch of their new ... treatment packs are specifically designed to reduce swelling ... a variety of applications. Researchers behind Thermal-Aid created ... corn to hold temperatures for long periods of ...
(Date:12/17/2009)... 30-Year Lease Agreement Will Help Stevens Hospital Expand, ... ,, EDMONDS, Wash., Dec. 17 The ... of Snohomish County today approved non-binding terms for ... Hospital to be effective this summer, pending regulatory ... to a hearing in mid-January to learn more ...
(Date:12/17/2009)... -- and adding to obesity epidemic, study says , , THURSDAY, ... for a new sofa, don,t despair: 22 percent of U.S. ... report finds. , In fact, the sale of high-calorie snack ... segments of the retail market, say the authors of the ... of Public Health . The easy availability of snack ...
Breaking Medicine News(10 mins):Health News:Patent Granted on GenerOs EX, A Medical Device That Helps Bones Grow 2Health News:Patent Granted on GenerOs EX, A Medical Device That Helps Bones Grow 3Health News:Holiday Aesthetics Special is Ageless Beauty Gift from Denver's Dr. Raval 2Health News:Holiday Aesthetics Special is Ageless Beauty Gift from Denver's Dr. Raval 3Health News:Thermal-Aid Bears Provide Warm Comfort to Children at Penny Lane for the Holidays 2Health News:Stevens Hospital to Affiliate with Swedish 2Health News:Stevens Hospital to Affiliate with Swedish 3Health News:Stevens Hospital to Affiliate with Swedish 4Health News:Wide Array of Stores Now Sell High-Calorie Snacks 2
... of the only tuberculosis vaccine approved for humans provided ... test, report scientists at The University of Texas Health ... Advance Online Publication March 1. Their findings resulted from ... National Institutes of Health (NIH). , Bacille Calmette-Gurin ...
... Calif., March 3 /PRNewswire/ -- ... that it is expanding the states in which ... the country,s largest private provider of emergency neurology ... than 5,500 emergency neurology consultations to date.(Logo: ...
... The Libyan Department of Relief and Humanitarian ... a significant capability for medical disaster response in ... experts from the American-based company BLU-MED Response Systems ... University where members of Libyan Aid erected the ...
... soles of their feet and the palms of their hands ... some types of chemotherapy. Patients, family members also can feel ... Both share a need for quick answers or more detailed ... or unexpected symptoms. , A new section of the ...
... (OTC Bulletin Board: PLCSF) announced today that it expects to ... fourth quarter and year ended December 31, 2008 before the ... to host a conference call to discuss those results at ... be joined via telephone by dialing (866) 356-3377 or (617) ...
... Her Quest to Raise One Million Dollars for Charity, Makes ... March 3 At 56, Linda Quirk has undergone an ... under a year. She began her trek across the ... has since gone on to run the Great Wall of ...
Other Medicine News:Health News:TB breakthrough could lead to stronger vaccine 2Health News:TB breakthrough could lead to stronger vaccine 3Health News:Specialists On Call Expands Access to Emergency Neurology On-Call Services in Montana 2Health News:Libyan Aid Tests 50-Bed BLU-MED Deployable Field Hospital 2Health News:Walther Cancer Foundation grant funds new IU Simon Cancer Center Web site section 2Health News:56-Year-Old Grandmother Heads to Antarctica to Run Her Seventh Worldwide Marathon in Under a Year 2Health News:56-Year-Old Grandmother Heads to Antarctica to Run Her Seventh Worldwide Marathon in Under a Year 3
... immunoassay system built around the many positive ... important addition of Logic Driven Incubation (LDI). ... for optimal performance with the fastest possible ... such as the cardiac biomarkers and HCG ...
... For The Detection ... Uses Of C-Peptide Measurement:, ... fasting hypoglycemia , Assisting ... diabetes mellitus , Differentiating ...
... for the quantitative determination of C-peptide in ... Automatic Immunoassay System. C-peptide measurement is used ... patients treated with insulin, to distinguish between ... various other diagnostic applications in patients with ...
... Multifocal IOL was designed to provide a ... glasses in most situations. While distance vision ... to that of a single vision monofocal ... and about 19 in 20 people with ...
Medicine Products: