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In First- and Second-Line Treatment of Clostridium Difficile Infection, Nearly 70 Percent of Surveyed Infectious Disease Specialists and Internists Will Use Fidaxomicin and Nearly Half Will Use CDA1/CDB1
Date:8/5/2010

eutic Area Director Danielle Drayton, Ph.D. "Over the past 12 months, 82 percent of surveyed infectious disease specialists observed an increase in the incidence of ESBL-producing enterobacteriaceae while more than half of surveyed clinicians also point to an increase in the incidence of CDI and MRSA. Drugs that target key gram-negative pathogens such as Pseudomonas aeruginosa and ESBL-producing enterobacteriaceae and Clostridium difficile stand to address a key unmet need and will capitalize on untapped market opportunities."

The report also finds that Forest/AstraZeneca/Takeda's ceftaroline and Trius's torezolid are the two late-stage emerging therapies that are most likely to gain formulary inclusion, according to surveyed P&T committee members. Seventy one percent of surveyed P&T committee members expect torezolid to be on formulary and 62 percent expect ceftaroline to be on formulary.

Hospital Anti-Infectives: Insights on the Uptake and Formulary Inclusion of Emerging Antibiotics and Antifungals—A Survey of Infectious Disease Specialists, Internists and P&T Committee Members is based on a U.S. survey of 51 infectious disease specialists, 52 internal medicine specialists and 21 infectious disease specialists who sit on their hospital's P&T committee.

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