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Imprimis to Begin New Study of Its Topical Analgesic Drug
Date:9/19/2012

SOLANA BEACH, Calif., Sept. 19, 2012 /PRNewswire/ -- Imprimis Pharmaceuticals, Inc. (IMMY:OTCQB) today announced the initiation of a clinical study of Impracor™, a topical cream that delivers a dose of the pain-relieving, anti-inflammatory drug ketoprofen. The study will measure the amount of ketoprofen found in the bloodstream following topical application of two different doses of the anti-inflammatory cream under different "real world' conditions, including normal activities, heat exposure to the application site and exercising on a treadmill. The amount of the drug in the bloodstream after taking an oral dose of ketoprofen will also be studied in healthy volunteers.

Impracor is designed to be applied to the site of muscle or joint pain, delivering a clinical dose of the active drug ketoprofen in its proprietary topical-delivery platform Accudel™ to the affected area. Current prescription ketoprofen (a non-steroidal anti-inflammatory drug, NSAID) is only available in an oral formulation in the US and is used to relieve pain and inflammation in various musculoskeletal conditions. Topical delivery of NSAIDs is recognized as safe pain medication that significantly reduces side effects, especially less stomach irritation, cardiac or liver problems compared with NSAIDs taken by mouth.

Imprimis believes its patented topical-delivery platform Accudel™ can also serve as a delivery vehicle for other medications.  Going forward, the company plans to employ a strategy of repurposing or reformatting existing FDA-approved generic drugs to be used in combination with Imprimis's delivery platform to create entirely new medications to address unmet therapeutic applications.

"We are pleased to achieve an important milestone for our company, which we expect to be the first of many such advances as we pursue FDA approval of our lead pain and anti-inflammatory product, Impracor™ and consider other potential product candidates
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SOURCE Imprimis Pharmaceuticals, Inc.
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