Navigation Links
ImpactRx Tracks Decline in Zetia and Vytorin Prescribing
Date:1/24/2008

Changes in prescribing behavior appear inconsistent with ACC statements on

ENHANCE study results

MOUNT LAUREL, N.J., Jan. 24 /PRNewswire/ -- ImpactRx, Inc., the pioneering force in measuring the impact of pharmaceutical promotion on physicians' prescribing behavior, has released data showing a sharp drop in prescribing Zetia and Vytorin since Merck / Schering-Plough's release of the ENHANCE study results on January 14. That study was designed to determine if ezetimibe (Zetia) and simvastatin used in combination was more effective than simvastatin alone in slowing the growth of plaque in the carotid artery. There was no statistically significant difference between treatment groups on the primary endpoint: mean change in the intima-media thickness (IMT) measured at three sites in the carotid arteries.

In the past week, primary care physicians' usage of Vytorin, the combination of Zetia and simvastatin, has declined from 15% of new treatment decisions to 5%. Among cardiologists, the decline has been less severe, from 15% of new treatment decisions to around 8%. Zetia's share of this treatment population has declined from about 8% to less than 5% among both PCPs and cardiologists. Switching from Vytorin and Zetia is driving this trend, along with less initial use among patients naive to drug therapy. As of yesterday, it appears this decline may have begun to stabilize.

"The reaction among physicians and patients is a bit puzzling," said John Kain, Vice President of Marketing at ImpactRx. "The American College of Cardiology released a statement recommending 'that major clinical decisions not be made on the basis of the ENHANCE study alone'. Both medicines were generally well tolerated and the overall incidence rates of cardiac events were nearly identical between both treatment groups, it concluded. The College specifically noted, 'There should be no reason for patients to panic'," Kain continued, "but the data certai
'/>"/>

SOURCE ImpactRx, Inc.
Copyright©2008 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2 3

Related medicine technology :

1. Zetia Does Not Reduce Carotid Plaque Size When Added to Zocor
2. ORTHO EVRA(R) Prescribing Information Updated
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013 Amgen (NASDAQ: AMGN ) will ... Conference on Thursday, May 30, 2013, at the Westin Boston ... a.m. Eastern Daylight Time. Arvind Sood , ... the conference. Live audio of the presentation can be accessed ... under Investors. A replay of the webcast will also be ...
(Date:5/23/2013)... recently published clinical study conducted at TOPS Comprehensive Breast ... that 3D mammography (breast tomosynthesis) significantly reduces unnecessary recalls ... study, "Implementation of Breast Tomosynthesis in a Routine Screening ... Stephen L. Rose , MD, and published in ... Roentgenology (AJR). The AJR is the scientific journal ...
(Date:5/23/2013)... Calif. , May 23, 2013 Anthem ... program that would have required them to obtain their ... by Consumer Watchdog and Whatley Kallas LLC.  ... Superior Court, alleged that Blue Cross,s mandatory mail order ... threatening their health and privacy. "This settlement ...
Breaking Medicine Technology:First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 2First Large-Scale U.S. Study Validates the Benefits of 3D Mammography (Breast Tomosynthesis) Exams 3Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 2Blue Cross To Allow HIV/AIDS Patients to "Opt-Out" of Mandatory Mail-Order Rx Drug Program, Announces Consumer Watchdog 3
... BIRMINGHAM, Ala., April 24, 2012 Today, the American Academy ... Cities for Life in Birmingham, Ala., a ... 26 million people living with diabetes in the U.S. and ... during their lifetime, Cities for Life , supported by ...
... Boston Scientific Corporation (NYSE: BSX ... of the Emerge™ PTCA[1] Dilatation Catheter.  The Emerge ... specifically to offer exceptional deliverability to address challenging ... immediately in CE Mark countries in both Monorail® ...
Cached Medicine Technology:American Academy of Family Physicians Foundation Launches Cities for Life 2American Academy of Family Physicians Foundation Launches Cities for Life 3American Academy of Family Physicians Foundation Launches Cities for Life 4Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter 2Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter 3Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter 4
(Date:5/24/2013)... HealthDay Reporter , , FRIDAY, May 24 (HealthDay ... are remarkable. But it was a physical challenge in ... of her sport. "I was an 11-year-old girl ... scoliosis was diagnosed by my orthopedic surgeon," said Lewis, ... Research Society and the American Academy of Orthopaedic Surgeons ...
(Date:5/24/2013)... 24, 2013 Western University of Health ... of “Full Accreditation” for the next seven years from ... (COE). , “This is a magnificent achievement, and one ... and student outcomes,” said College of Veterinary Medicine Dean ... appreciation to the faculty, staff, preceptors, and students that ...
(Date:5/24/2013)... KC and Monica Craichy, Founders of Living Fuel, Inc ... Kyle and Austin Craichy, will be kiteboarding with members of ... , KC Craichy said he is excited to be involved ... that virtually everyone who planned to be involved is going ... meet at Matheson Hammock Park and Beach in Miami at ...
(Date:5/24/2013)... The Mirena IUD lawyers at the ... FDA has received more than 59,229 complaints since 2004 from ... birth control device known as the Mirena IUD.* , Among ... the women “included ‘expulsion,’ where the IUD came out on ... to an ABC News article. “Abdominal pain is also common, ...
(Date:5/24/2013)... E-Dentists.com has announced the launch of their new ... a leading medical Internet marketing agency. , ... focus on providing dentists the help they need to ... keywords. The dental SEO analysis covers a full analysis ... their competitors are doing right. The goal is to ...
Breaking Medicine News(10 mins):Health News:Top-Ranked Golfer Beats Scoliosis 2Health News:Top-Ranked Golfer Beats Scoliosis 3Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 2Health News:FreeRide836 Sponsor Living Fuel, The Leader in Superfood Nutrition, Announces Kiteboard Launch For This Sunday To Raise Money For Orphans In Africa 3Health News:Sufferers of Alleged Mirena IUD Side Effects Lodge More Than 59,000 Complaints With FDA, Rottenstein Law Group LLP Notes 2Health News:Dental SEO Analysis Launched by E-Dentists.com in Partnership with JD Media Surge 2
... poses a significant threat to human health by labeling healthy ... Ray Moynihan, Senior Research Fellow at Bond University in Australia, ... The feature comes as an international conference ... United States, hosted by The Dartmouth Institute for Health Policy ...
... , WEDNESDAY, May 30 (HealthDay News) -- Nearly one ... they can be triggered by hot summer weather. Hives are ... The condition can be acute or chronic, according to the American ... last less than a day or up to six weeks, are ...
... Children today may be busier than ever, but Case ... hasn,t suffered in fact, it appears to have ... expected the opposite outcome when they analyzed 14 play ... ( http://www.youtube.com/watch?v=sQb95itdoCM ). But as they report in ...
... shows that it is beneficial to have a loved ... study led by researchers at the Johns Hopkins Bloomberg ... true for older adults suffering from poor mental health. ... visits helps or hinders physician visit processes and found ...
... M.D., principal investigator at The Los Angeles Biomedical Research ... investigator of a project that was just awarded a ... Medicine (CIRM). The goal of the project is ... treatment of mucopolysaccharidosis I (MPS I), a fatal pediatric ...
... TUESDAY, May 29 (HealthDay News) -- Women who develop fevers ... have a child with autism spectrum disorder or another developmental ... if, fevers may increase the risk for autism is unknown, ... if they do develop a fever while pregnant because taking ...
Cached Medicine News:Health News:Overdiagnosis poses significant threat to human health 2Health News:Overdiagnosis poses significant threat to human health 3Health News:Summer's Heat May Enflame Hives 2Health News:Despite less play, children's use of imagination increases over 2 decades 2Health News:Patient mental health overlooked by physician when a family member is present 2Health News:LA BioMed's Dr. Patricia Dickson researching treatments for neurodegenerative disorders 2Health News:Fever During Pregnancy May Raise Odds for Autism in Offspring 2Health News:Fever During Pregnancy May Raise Odds for Autism in Offspring 3
... Biosense Webster offers a complete line ... in the atrium. The ISMUS CATH ... simple placement in the atrial isthmus. ... the catheter's distal tip permit pacing ...
... Biosense Webster is the source for ... catheters for left-sided mapping - all with ... come to expect from the leader in ... catheters are specifically designed and constructed to ...
... Inquiry H Steerable Catheter. ... a variety of designs and ... catheter stability. 10 to 24 ... curves, inactive and active tip ...
A steerable diagnostic catheter with optimal maneuverability...
Medicine Products: