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Immunotherapies Will Continue to Dominate the Malignant Melanoma Drug Market with Sales of Immune Checkpoint Inhibitors Accounting for Majority of Sales in this Drug Class in 2022
Date:12/19/2013

e first of which will be GlaxoSmithKline's Tafinlar/Mekinist, in 2014, in the United States and Europe. All BRAF/MEK inhibitor combination therapies will compete for market share in the unresectable/metastatic BRAF V600-mutation-positive patient population, with sales of this drug class accounting for one-fifth of the total market in 2022.

The report also finds that, despite the anticipated launch of several novel premium-priced therapies during the 2012-2022 forecast period, Yervoy will remain the sales leader through 2022 due to the agent's high price, its anticipated line-extension into the adjuvant setting and its anticipated first-line use in combination with nivolumab for unresectable/metastatic disease.

"When considering the melanoma clinical development pipeline, interviewed thought leaders are most excited about the immune checkpoint inhibitors," said Decision Resources Senior Business Insights Analyst, Karen Pomeranz, Ph.D. "We forecast that nivolumab and MK-3475 will launch for treatment of melanoma in all markets under study, attaining their highest sales in the first-line unresectable/metastatic setting. In 2022, nivolumab and MK-3475 will earn overall major market sales of nearly $1.1 billion."

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Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources Group company.

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