Navigation Links
Immunomedics Announces Preclinical Therapy Results of SN-38 Immunoconjugate for Colorectal Cancer
Date:1/20/2009

creased 4-fold to 86 days compared to untreated animals, and was significantly better than all controls, including irinotecan administered at its maximum tolerated dose, which is a 50-fold increase in the amount of free drug than SN-38 in the immunoconjugate dose.

"We believe these results suggest that targeted chemotherapy of colorectal cancer with labetuzumab-SN-38 should enhance the bioavailability and reduce the toxicity of the clinically validated drug, irinotecan," commented Cynthia L. Sullivan, President and CEO. "More preclinical evidences are being collected to support the human testing of this new drug immunoconjugate," she added.

About Immunomedics

Immunomedics is a New Jersey-based biopharmaceutical company primarily focused on the development of monoclonal, antibody-based products for the targeted treatment of cancer, autoimmune and other serious diseases. We have developed a number of advanced proprietary technologies that allow us to create humanized antibodies that can be used either alone in unlabeled or "naked" form, or conjugated with radioactive isotopes, chemotherapeutics or toxins, in each case to create highly targeted agents. Using these technologies, we have built a pipeline of therapeutic product candidates that utilize several different mechanisms of action. We also have a majority ownership in IBC Pharmaceuticals, Inc., which is developing a novel Dock-and-Lock (DNL) methodology for making fusion proteins and multifunctional antibodies, and a new method of delivering imaging and therapeutic agents selectively to disease, especially different solid cancers (colorectal, lung, pancreas, etc.), by proprietary, antibody-based, pretargeting methods. We believe that our portfolio of intellectual property, which includes approximately 134 patents issued in the United States and more than 300 other patents issued worldwide, protects our product candidates and technologie
'/>"/>

SOURCE Immunomedics, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Modigene Announces Positive Results of Pilot Toxicity Study of Its Long-Acting Human Growth Hormone hGH-CTP
2. Kyowa Hakko Kirin Announces Development Policy for Anti-Parkinsons Disease Drug KW-6002 (Istradefylline)
3. Intra-Cellular Therapies Announces Successful Outcome of a Phase II Clinical Trial with ITI-007 in Patients with Sleep Maintenance Insomnia
4. Beactica Announces Fragment-Based Drug Discovery Research Collaboration With GE Healthcare and Uppsala University
5. Amicus Therapeutics Announces Positive Progress of Three Lead Clinical Programs and General Outlook for 2009
6. NeurogesX Announces Publication of Phase 3 Data for QUTENZA(TM) (NGX-4010) in Postherpetic Neuralgia (PHN) by The Lancet Neurology
7. Pulmo BioTech Inc. Announces Dual Listing on Frankfurt Borse
8. Human Genome Sciences Reports Substantial Progress Toward Commercialization and Announces 2009 Goals at JPMorgan Healthcare Conference
9. Anesiva Announces FDA Approval of Supplemental New Drug Application to Expand Zingo(TM) Indication
10. ProUroCare Medical Inc. Announces Pricing of Equity Offering
11. Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... 2014  Low T Center endorses the recommendations ... Hyattsville, Maryland earlier this week. The ... patient population for testosterone therapy (TRT), as well ... TRT. Examining recent claims from studies that TRT affects ... studies do not provide convincing evidence that TRT ...
(Date:9/18/2014)... Ky. , Sept. 18, 2014 /PRNewswire/ ... innovative laboratory technologies and products to hospitals, ... announced today an amended distributorship agreement with ... reagents, controls and instruments, including the Sysmex ... Sysmex XP-300™, XT-Series and XN-Series Automated Hematology ...
(Date:9/18/2014)... Research and Markets  has announced the addition of ... Columns Market" report to their offering. ... enantiomers of the same compound with different affinities for ... possessing different elution times. Chiral stationary phases are generally ... chiral separation chromatography columns market is growing at a ...
Breaking Medicine Technology:Low T Center Endorses The Joint FDA Committee Meeting on Testosterone 2LABSCO Renews Sysmex Distributorship Agreement 2LABSCO Renews Sysmex Distributorship Agreement 3Micro Market Monitor: Global Chiral Separation Columns Market 2
... Feb. 7, 2011 Beckman Coulter, Inc. (NYSE: ... and marketer of products that simplify, automate and ... technology leader that designs, manufactures, and markets innovative ... commercial customers, announced today that they have entered ...
... (Nasdaq: GXDX ) announced today that the Federal ... under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as amended ... Novartis to purchase all outstanding shares of common stock of ... the HSR Act waiting period satisfies one of the conditions ...
Cached Medicine Technology:Danaher to Acquire Beckman Coulter, Inc. 2Danaher to Acquire Beckman Coulter, Inc. 3Danaher to Acquire Beckman Coulter, Inc. 4Danaher to Acquire Beckman Coulter, Inc. 5FTC Grants Early Termination of Waiting Period Under Hart-Scott-Rodino Act 2
(Date:9/18/2014)... Mary Ann Thompson and Mathieu Nikel decided it was time to ... their son, Isaac, said there was only one choice for them ... 2001 when Thompson was an undergraduate student and needed a French ... time, was French and so she asked him. , ... when she was 7 years old. Nikel is originally from ...
(Date:9/18/2014)... Kent, WA Chiropractor Danene Saggau ... to announce that Dawn Kelly has agreed to become the ... looks forward to Ms. Kelly expanding her role within the ... her a key contributor. “ Dawn Kelly brings to ... personal experiences that will allow me to focus on ...
(Date:9/18/2014)... 2014 Memorial Cardiac and Vascular ... week by performing the first ever, adult heart transplant ... for Organ Sharing) approval to launch the adult heart ... two programs in South Florida. , The skilled ... Gongora, Medical Director of the Adult Heart Transplant ...
(Date:9/18/2014)... 18, 2014 (HealthDay News) -- Exposure to diverse communities ... study. Hearing different languages in the park ... to learn from people who are different from them, ... like adults, are often biased against interacting with and ... Amanda Woodward, a University of Chicago psychology professor, said ...
(Date:9/18/2014)... By Steven Reinberg HealthDay ... a sign that the Ebola outbreak in West Africa is starting ... that more than 700 new cases of the deadly viral infection ... number of cases to more than 5,300, with roughly half of ... reported. The number of deaths now tops 2,600. WHO ...
Breaking Medicine News(10 mins):Health News:For The First Time in Over a Decade Mercy College Alumni Marry at College 2Health News:Lake Meridian Chiropractic of Kent, WA Announces that Dawn Kelly Has Been Promoted to the Position of Office Manager 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 2Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 3Health News:Memorial Cardiac & Vascular Institute Performs First Adult Heart Transplant in Broward County 4Health News:Study: Exposure to Diversity Might Boost Baby's Social Skills 2Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 2Health News:New Ebola Cases Top 700 in Just One Week, Officials Report 3
... of low health literacy the difference between patients, ... effectively communicate complex medical information is $106 billion ... biopharmaceutical company. To improve the health literacy of professionals ... health literacy study emphasis beginning this fall. The MU ...
... , ... Government Agencies to Increase ROI of IT Infrastructure , ... Reston, VA (PRWEB) February 18, 2010 -- Carahsoft ... Parabonâ Computation , a veteran provider of extreme-scale grid computing software and services. ...
... ... software standardization program at seven hospital laboratories of the Cleveland Clinic in Ohio. ... ... healthcare diagnostic information technology and outreach solutions, has successfully completed system-wide implementation of ...
... Rat studies suggest Victoza could spur rare thyroid tumor, ... THURSDAY, Feb. 18 (HealthDay News) -- The U.S. Food ... January to approve a new diabetes drug, Victoza (liraglutide), ... risk for a rare thyroid cancer. , Victoza, among ...
... (Feb. 17, 2010) Van Andel Research Institute ... sunitinib, a treatment that is currently the first line of ... form of kidney cancer. Most patients who show a ... after one year of treatment. Kidney cancer is among ...
... , ST. PETERS, Mo. , Feb. 18 ... Electronic Materials, Inc., has donated $25,000 to Meds & ... charity dedicated to saving the lives of Haiti ,s malnourished ... Kids produces peanut-based ready-to-use therapeutic food (RUTF) – known in ...
Cached Medicine News:Health News:MU offers training program to improve health literacy 2Health News:Parabon's Frontier Grid Platform Software Now Available on Carahsoft's GSA Schedule 2Health News:Parabon's Frontier Grid Platform Software Now Available on Carahsoft's GSA Schedule 3Health News:Sunquest Completes System-Wide Implementation at Cleveland Clinic Hospital Laboratories 2Health News:FDA Approved Diabetes Drug Despite Hints at Cancer Risk 2Health News:FDA Approved Diabetes Drug Despite Hints at Cancer Risk 3Health News:VARI findings may help patients with deadly kidney cancer 2Health News:MEMC Foundation Donates to Help Fight Malnourishment in Haiti 2Health News:MEMC Foundation Donates to Help Fight Malnourishment in Haiti 3
ELISA Test System for the detection of HBc...
Test for Anti-HBc for use on the Abbott Prism...
... flexible meter for Point of ... Accu-Chek Inform System offers user-friendly, ... the only Point of Care ... the entry and automatic transfer ...
... Introducing BenchMark XT® the only ... the flexibility you need to expand ... and improve your slide turnaround time. ... You choose how to use the ...
Medicine Products: