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ImmuneRegen BioSciences, Inc. Demonstrates Radilex(TM) Increases Disease-Fighting White Blood Cells
Date:8/27/2007

ImmuneRegen and TGen Continue Testing Possible Treatment for Acute Radiation Syndrome or Radiotherapy Adjuvant Likely Targeting Adult Stem

Cells in Bone Marrow

SCOTTSDALE, Ariz., Aug. 27 /PRNewswire-FirstCall/ -- ImmuneRegen BioSciences, Inc., a wholly owned subsidiary of IR BioSciences Holdings, Inc. (OTC Bulletin Board: IRBO), today announced that initial studies at TD2 (TGen Drug Development Services), an affiliate of The Translational Genomics Research Institute (TGen) have found ImmuneRegen's Radilex (TM) to protect mice from the near total destruction of circulating white blood cells following radiation exposure. These findings support past data and provide further insight into possible mechanisms underlying the activity of Radilex as well as suggest possible therapeutic areas in which Radilex could play a role as a potential treatment.

In previous studies of lethally irradiated mice, Radilex was shown to enhance survival and increase white blood cells in surviving animals. In the recent studies, a sub-lethal dose of radiation induced a 90-95% decrease in circulating white blood cell levels. Administered shortly following radiation exposure, Radilex was able to subsequently increase circulating levels of monocytes, granulocytes and lymphocytes in all treated animals.

"The results of this study have strengthened our confidence that Radilex(TM) may prove to be a life saving treatment candidate as well as a drug and treatment enhancement candidate," says Michael K. Wilhelm, Co-Founder and CEO of ImmuneRegen BioSciences, Inc. "We are very happy that our relationship with TGen continues to develop a promising collection of data on Radilex's ability to potentially preserve human life after lethal or sub-lethal exposure to radiation."

Low circulating white blood cell counts (leukopenia or leukocytopenia) can be due to a number of causes, among them infections (including certain viral infections such as
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SOURCE ImmuneRegen BioSciences, Inc.
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