Navigation Links
Imaging Results From the ADAGIO-LIPIDS Reveal That Effects of Rimonabant on Cardiometabolic Risk Profile Include Loss of Visceral Fat and Mobilization of Liver Fat
Date:4/29/2008

or the first time that rimonabant induced a significant mobilization of liver fat (decrease in the fatty liver index, p<0.005) which was associated with a significant improvement in ALT levels (p<0.001), a commonly used marker of liver function also associated with the features of the metabolic syndrome" he added.

As CB1 receptors are located in organs other than the brain, such as the adipose tissue and the liver, results of ADAGIO-LIPIDS are consistent with the hypothesis that antagonism of the these peripheral CB1 receptors could slow lipogenesis in both adipose tissue and the liver, leading to loss of both visceral and liver fat.

Regarding safety, as patients previously treated for symptoms of depression were excluded from the ADAGIO-LIPIDS trial, the incidence of side effects leading to discontinuation was essentially similar to the previously published phase III studies. "These results provide further evidence of the acceptable safety profile of rimonabant provided that the drug is used as currently recommended in clinical practice. Patients with a history of depression or on anti-depressants should not be treated with rimonabant." emphasized Dr Despres.

"As we now have evidence that patients with visceral obesity represent the subgroup of overweight/obese patients with an activated endocannabinoid system, results of ADAGIO-LIPIDS provide support to the notion that patients with visceral obesity who are often either dyslipidemic or with type 2 diabetes (or both) represent a relevant subpopulation of overweight/obese patients who would particularly benefit from rimonabant therapy" jointly concluded Dr Despres and Ross.

About Hopital Laval

Founded in 1918, Hopital Laval is the heart and lung institute of Universite Laval. It provides the population of Central and Eastern Quebec with subspecialized care and services in cardiology, pneumology, and the surgical management of obesity. The Hospital's expertise includes ambulatory an
'/>"/>

SOURCE Hopital Laval
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Caliper Life Sciences Optical Imaging Technology Selected to Aid Tuberculosis Research Efforts by the Texas A&M Health Science Center
2. Repligen Receives FDA Fast Track Designation for RG1068 for Pancreatic Imaging
3. Repligen Initiates Phase 3 Clinical Trial of RG1068 for Pancreatic MRI Imaging
4. FluoroPharma Announces Commencement of Phase I Clinical Trial for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)
5. Bertrand Study Finds Significant Value in Breast-Specific Gamma Imaging (BSGI) as an Adjunctive Procedure in Breast Diagnostics
6. FluoroPharma Announces Positive Phase I Safety Results for CardioPET(TM), Coronary Artery Disease (CAD) Imaging Tracer for Positron Emission Tomography (PET)
7. Stereo Mammography Takes Breast Imaging to a New Dimension
8. Imaging Diagnostic Systems Updates PMA Filing Status for the New CT Laser Breast Imaging System
9. Imaging Diagnostic Systems CTLM Technology Presented at Congress of World Society for Breast Health
10. Siemens Preclinical Imaging System Helps The Methodist Hospital in Houston Further Its Research Mission
11. XTENT Announces First Quarter 2008 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... , Sept. 19, 2014  4WEB Medical announces ... 3D-printed foot and ankle osteotomy implants on the ... Ankle Society annual meeting in Chicago ... all of a surgeon,s osteotomy needs with 74 size options ... systems had smaller offerings of only 15 to 18 implant ...
(Date:9/19/2014)... Mich. , Sept. 19, 2014  Diplomat, the ... of David Dreyer to the Board of ... independent director and will also serve as chair of ... almost 30 years of accounting, financial, compliance and operating ... Mr. Dreyer has served as chief financial officer, chief ...
(Date:9/19/2014)... -- According to market research report, ... & Laboratory), Industry (Food, Pharmaceutical, Biotechnology, Surgical Procedure, ... Geography - Global Trends & Forecast to 2019", ... market on the basis of various types, applications, ... market size of each of these segments in ...
Breaking Medicine Technology:4WEB Medical Unveils 3D-Printed Osteotomy Truss System 2David Dreyer Appointed to Diplomat Board of Directors 2Lyophilization Market Worth $5,121.5 Million by 2019 2Lyophilization Market Worth $5,121.5 Million by 2019 3
(Date:9/19/2014)... made from the wonder material graphene has been used ... developing cancer. , The biosensor has been shown ... bioassay tests currently in use, and was able to ... the possibility of a rapid, point-of-care diagnostic tool for ... September, in IOP Publishing,s journal 2D Materials . ...
(Date:9/19/2014)... 2014 Follow us on LinkedIn ... medical imaging market, are engineered to enhance the anatomic ... past three decades have expanded the application roles of ... based agents used for over half a century to ... agents have witnessed sea changes, revolutionizing in the process ...
(Date:9/19/2014)... 2014 The Nordic ... style of eating, is making its way ... Doc’s medical weight loss programs, ... good food which leads to improved health. ... patients to understand how diet can impact ...
(Date:9/19/2014)... Recent financial data reveled ... their sales by 7% in the last quarter of ... can be used as a bellwether to determine how ... data has been proven to show trends with shipments ... Other non-trucking data is largely influenced by international and ...
(Date:9/19/2014)... Baltimore, MD & Salt Lake City, UT (PRWEB) September ... pleased to launch the new Activz Greens Smoothie ... Natural Products Expo East, September 18th-20th in Baltimore, ... powder with 8 organic super foods combined in one ... at Natural Products Expo East, September 18th-20th in Baltimore, ...
Breaking Medicine News(10 mins):Health News:Graphene sensor tracks down cancer biomarkers 2Health News:New Clinical Applications and Advanced Imaging Capabilities Drive Growth in the Imaging Agents Market, According to New Report by Global Industry Analysts, Inc. 2Health News:New Clinical Applications and Advanced Imaging Capabilities Drive Growth in the Imaging Agents Market, According to New Report by Global Industry Analysts, Inc. 3Health News:New Clinical Applications and Advanced Imaging Capabilities Drive Growth in the Imaging Agents Market, According to New Report by Global Industry Analysts, Inc. 4Health News:Diet Doc’s Medical Weight Loss Programs Announce Diet Plans Based on the Same Principles as the New Nordic Diet 2Health News:Diet Doc’s Medical Weight Loss Programs Announce Diet Plans Based on the Same Principles as the New Nordic Diet 3Health News:Diet Doc’s Medical Weight Loss Programs Announce Diet Plans Based on the Same Principles as the New Nordic Diet 4Health News:LeaseQ Announces Good News For The Truck Leasing Industry As Truck Rentals In The U.S Continues to Gain Traction 2Health News:LeaseQ Announces Good News For The Truck Leasing Industry As Truck Rentals In The U.S Continues to Gain Traction 3Health News:New Activz Greens Smoothie with 8 Organic Superfoods & More Launched at Natural Products Expo East 2Health News:New Activz Greens Smoothie with 8 Organic Superfoods & More Launched at Natural Products Expo East 3
... America, doctors who look after animals are best placed ... , Urging veterinarians to work more closely with ... Julie Gerberding, director of the Atlanta-based federal Centers for ... of the last 14 new infectious diseases that have ...
... till now; as she was seen sporting a T-shirt with ... figure Andy Warhol . ,The socialite, who ... in social service after finishing jail term, was spotted visiting ... present at a screening of Michael Moore's latest documentary Sicko. ...
... acid to flour considerably reduces congenital malformations . ... Social and Preventive Medicine, has suggested that the addition ... 46 percent slump in the incidence of congenital neural ... ,Such deformations either result in the ...
... a young person drinks is largely determined by how much others ... more, a new study has found . ,The study ... men, and people with positive expectations regarding alcohol drink more. ... to 25 years, most of whom did not live at home. ...
... the largest in the US, is believed to have agreed ... such settlement in recent history . ,The amount, ... plaintiff, exceeded earlier reports that the settlement would be between ... orders the Servites, Claretians and Oblates will be ...
... three from Brisbane, Queensland in Australia died on September 23, ... She was apparently felled by a toxic combination of alcohol ... ,She had gone on the cruise with her 12-year-old ... with. ,Toxicology reports later revealed that the ...
Cached Medicine News:Health News:Vets To Team Up With Human Health Specialists 2Health News:Adding Folic Acid to Flour Lessens Congenital Malformations 2Health News:Los Angeles Diocese Opts for Huge Payout in Sexual Abuse Cases 2Health News:Inquest of Date-rape Drug Victim Attracts Wide Attention in Australia 2Health News:Inquest of Date-rape Drug Victim Attracts Wide Attention in Australia 3
... pumps deliver critical performance for all vacuum ... optimizes pump performance to suit all applications. ... convenient checking of proper oil levels at ... is designed to work with all Thermo ...
... Vacuum Source is a combination instrument bringing together ... Oil-free Vacuum Pump. It is designed to handle ... Combines a Refrigerated Cold Trap + ... extra tubing connections. , ...
... Vacuum Pump is designed for a wide variety ... quiet running and eliminates oil mist vapors because ... operate. Less mess, less fuss., Quiet, ... chemically resistant solid ETFE and PFA heads ...
... two-stage, oil-sealed, rotary vane vacuum pumps specifically ... pump comes complete with a GBORK (Gas ... Mist Filter (EMF-10). The GBORK allows the ... keep the oil clean without losing oil. ...
Medicine Products: