Navigation Links
Ikaria Completes Dosing of Phase 1a Clinical Study for IK-1001 (Sodium Sulfide) for Injection
Date:5/19/2008

e regulatory bodies, we expect to start later this year."

Daniel Tasse, President & CEO of Ikaria, remarked, "IK-1001 is an important addition to our growing portfolio of clinical-stage drug development candidates, which includes Covox(R) (carbon monoxide) for inhalation in Phase 2 trials and INOmax(R) (nitric oxide) for inhalation, which is already on the market, as well as in multiple Phase 2 and Phase 3 trials. Although these drug candidates are targeted for different indications and patient populations, all share a common goal of providing therapeutic options for currently unmet critical care needs. It is Ikaria's mission to develop novel treatments for the critically ill in the in hospital and ICU setting -- an area of medicine that is highly underserved, yet represents a multi-billion-dollar market."

Hydrogen sulfide is more commonly known as a toxic gas at high levels, but has demonstrated a biologically protective role when delivered in very low doses. Based upon research on the bioactivity of the gaseous signaling molecule hydrogen sulfide, or H2S, Ikaria is investigating the impact of the sulfide ion, administered as sodium sulfide, in a number of disease models. Preclinical data demonstrate the therapeutic potential of IK-1001 (sodium sulfide) for injection, a parenteral injectable formulation of hydrogen sulfide, in a variety of disease models including myocardial infarction, cardiopulmonary bypass surgery, thoracoabdominal aortic aneurysm surgery, liver ischemia and reperfusion, organ storage and transplantation and acute lung injury.

Mark Roth, Ph.D., a member of the research faculty of the Hutchinson Cancer Research Center (FHCRC), noted, "The fact that IK-1001 progressed from the early concept stage into the completion of this Phase 1 trial in less than 18 months speaks volumes about the quality and innovative spirit of the R&D group at Ikaria." In a landmark article in the prestigious journal, Science, Dr. Roth demonstrated the
'/>"/>

SOURCE Ikaria Holdings, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Cerenis Therapeutics Completes Phase I Clinical Trial of CER-002 for Treatment of Cardiovascular Disease
2. Novavax Completes Enrollment in Phase I/IIa Pandemic Influenza Vaccine Clinical Trial
3. VIA Pharmaceuticals Completes Enrollment in Phase 2 Acute Coronary Syndrome (ACS) Trial
4. PacificGMP Completes GMP Product Fill for Trius Therapeutics
5. Cardinal Health Completes Enturia Acquisition
6. DaVita Clinical Research Completes Record Number of Renal Trials in 2007
7. Globus Medical Completes Enrollment Of SECURE(R)-C Cervical Artificial Disc Clinical Trial
8. Poniard Pharmaceuticals Completes Enrollment of Phase 2 Picoplatin Trial in Colorectal Cancer
9. Alexza Completes Enrollment in Phase 2a Clinical Trial With AZ-002 (Staccato(R) Alprazolam) in Panic Disorder Patients
10. Peregrine Pharmaceuticals Completes Patient Enrollment in First Stage of Bavituximab Phase II Breast Cancer Trial
11. Nventa Completes Safety Evaluation on Final Cohort in HspE7 Phase 1 Cervical Dysplasia Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... 5, 2015  InMed Pharmaceuticals Inc. ("InMed") (CSE: ... that specializes in developing safer, more effective cannabis-based ... investor, and Non-Executive Director, Peter Mountford , ... with primary responsibility for the European markets. ... leverage his previous success in the emerging field ...
(Date:5/4/2015)... Wash. and VANCOUVER, British Columbia ... (NASDAQ: OGXI ) announced today that it will ... May 14, 2015. Company management will host a conference ... to provide an overview of financial results, clinical development ... To access the webcast, log on to the Investor ...
(Date:5/4/2015)... , May 4, 2015  Amgen (NASDAQ: AMGN ... Conference at 8 a.m. ET on Thursday, May 7, 2015, ... Anthony C. Hooper , executive vice president of Global Commercial ... of the presentation can be accessed from the Events Calendar ... of the webcast will also be available on Amgen,s website ...
Breaking Medicine Technology:InMed Engages Peter Mountford as Strategic Advisor 2InMed Engages Peter Mountford as Strategic Advisor 3InMed Engages Peter Mountford as Strategic Advisor 4Amgen To Present At The Deutsche Bank 40th Annual Healthcare Conference 2
(Date:5/5/2015)... Brookfield, Wis. (PRWEB) May 05, 2015 ... security solutions created the Sensatec® ST750 Fall Management Solution ... recording advising the monitored patient or resident to wait ... up. Caregivers also have the choice of 16 different ... into a nurse call system such as Code Alert®. ...
(Date:5/5/2015)... May 05, 2015 Sheltering Arms held ... Walt “Clyde” Frazier and Cravath, Swaine & Moore LLP ... highest-need communities. The event was co-chaired by Vanguard sponsors ... “The Next Chapter” highlighted Sheltering Arms’ significant growth in ... unveiled in February 2015. Formerly Episcopal Social Services, Sheltering ...
(Date:5/5/2015)... May is National Osteoporosis Month, and also marks ... Bone Health . Founded by Charles T. Price, MD, the ... and physicians about the latest advances in bone care, and ... to a study recently published by the Journal of Bone ... osteoporosis and low bone mass. This breaks down to a ...
(Date:5/5/2015)... 05, 2015 Care Logistics ... called “Medicare Breakeven Challenges? A Model to ... ,     Formulas for two critical ... but should be ,     A model ... space” and ensures sustained efficient operations , ...
(Date:5/5/2015)... Kan. (PRWEB) May 05, 2015 After ... healthcare leadership solutions firm B. E. Smith, West ... Bradley Pfeifer as chief executive officer. A skilled healthcare ... Pfeifer will assume his new duties on June 1st. ... strategy as well as a keen understanding and success ...
Breaking Medicine News(10 mins):Health News:RF Technologies® Releases Sensatec® ST750 Voice Alarm for Fall Management 2Health News:RF Technologies® Releases Sensatec® ST750 Voice Alarm for Fall Management 3Health News:Sheltering Arms Honors Walt "Clyde" Frazier and Cravath, Swaine & Moore LLP at Annual Gala 2Health News:The Institute for Better Bone Health Observes National Osteoporosis Month, Celebrates Three Years of Promoting Healthy Bones 2Health News:The Institute for Better Bone Health Observes National Osteoporosis Month, Celebrates Three Years of Promoting Healthy Bones 3Health News:Care Logistics Publishes a New Hospital Guidebook for Achieving Medicare Breakeven 2Health News:West Holt Medical Services Hires New Chief Executive Officer 2Health News:West Holt Medical Services Hires New Chief Executive Officer 3
... (HealthDay News) -- The experience of killing in war is ... U.S. veterans of the Vietnam War. Researchers analyzed data ... War veterans and found that those with more killing experiences ... with fewer or no experiences of killing. The experiences ...
... HealthDay Reporter , MONDAY, April 23 (HealthDay News) ... eases autism symptoms are more likely to get published ... improve common behaviors such as rocking and hand-flapping, new ... physicians believe the medications -- known as selective serotonin ...
... and Damon could be the kids up the block. Briana ... sister,s footsteps to college. Damon works hard at an after-school ... and try to stay out of trouble. , But Briana ... are a pair of digitally animated street-smart characters with a ...
... have developed a new instrument to measure work addiction: ... based on core elements of addiction that are recognised ... seem to be driven to work excessively and compulsively. ... In the wake of globalisation, new technology and ...
... It goes without saying that bites from venomous snakes can ... expensive, an expert warns. Medical bills of $50,000 or ... venomous snake, said Jill Heatley, an associate professor of veterinary ... total cost includes hospitalization, which can last from one day ...
... 2012 Most people go through life setting goals ... makes those goals become unachievable or even unhealthy? ... by Carsten Wrosch of Concordia University,s Department of ... Catherine Sabiston of McGill,s Department of Kinesiology and Physical ...
Cached Medicine News:Health News:Wartime Killing May Raise Veterans' Thoughts of Suicide 2Health News:'Publication Bias' Casts Doubt on Value of Antidepressants for Autism 2Health News:'Publication Bias' Casts Doubt on Value of Antidepressants for Autism 3Health News:Animated characters keep it real in teen violence prevention videos 2Health News:Animated characters keep it real in teen violence prevention videos 3Health News:New method to measure work addiction 2Health News:Cost of Snakebite Therapy May Squeeze Victims' Wallets 2Health News:Letting go can boost quality of life 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: