Navigation Links
ISTA Pharmaceuticals Reports Positive Preliminary Results from its Phase 1/2 Clinical Study of Bepotastine Besilate Nasal Spray for the Treatment of Symptoms Associated with Seasonal Allergic Rhinitis
Date:10/6/2010

nasal symptoms, with the most rapid improvement seen for drug-related reductions in sneezing and nasal itching.

The PK information collected in the study supported the principle that the systemic bioavailability of bepotastine from the nasal sprays approximated dose proportionality. With regards to safety, the total number of adverse events was similar in all treatment groups, with the most common adverse events reported being bitter taste, headache, nasal pain and discomfort, and nosebleed. These adverse events were generally mild. Additionally, no serious adverse events were observed during the Phase 1/2 study.  

About Allergic Rhinitis

According to the American Academy of Allergy Asthma & Immunology (AAAAI), approximately 60 million Americans are affected by allergic rhinitis, an inflammation of the nasal passages caused by exposure to certain allergens, such as pollen from trees, grass and plants, animal dander, feathers, dust mites and molds. Allergic rhinitis is characterized by a number of symptoms, including sneezing, nasal congestion, nasal itching and runny nose.  The eyes, ears, sinuses, and throat also can be affected. Current treatments for allergic rhinitis include antihistamines, mast cell stabilizers, anti-inflammatories, and steroids.  Based on data from IMS Health in the U.S., approximately 43.3 million prescriptions were filled for nasal allergy treatments in 2009, resulting in sales of approximately $2.2 billion.

About bepotastine besilate

Bepotastine besilate is a non-sedating, highly selective antagonist of the histamine H1 receptor.  It has a stabilizing effect on mast cells, and it suppresses the migration of eosinophils into inflamed tissues.  The compound's primary mechanisms of action are believed to make it an effective treatment for nasal symptoms associated with allergic rhinitis.

Bepotastine besilate has been approved in Japan for systemic use in the
'/>"/>

SOURCE ISTA Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. MAP Pharmaceuticals Announces Exercise of Over-Allotment Option and Closing of Underwritten Offering of Common Stock
2. Savient Pharmaceuticals Announces Dismissal of Class Action Lawsuit
3. Jiangbo Pharmaceuticals Announces Fourth Quarter and Fiscal Year 2010 Results
4. Transcept Pharmaceuticals to Present at BIO Investor Forum
5. MAP Pharmaceuticals, Inc. Announces Pricing of Underwritten Registered Offering of Common Stock
6. Qualitest Pharmaceuticals Selects TrackWise® for Comprehensive Enterprise Quality and Document Management
7. Prolong Pharmaceuticals Names Industry Veteran Glenn Kazo President
8. Tigris Pharmaceuticals, Inc. Completes $6.5 Million Private Placement
9. Tigris Pharmaceuticals Appoints Neil Flanzraich to Executive Chairman of the Board
10. Endo Pharmaceuticals Announces Agreement to Acquire Qualitest Pharmaceuticals for $1.2 Billion
11. Valeant Pharmaceuticals Announces Redemption and Defeasance of 7.625% Senior Notes Due 2020 and 8.375% Senior Notes Due 2016
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/2/2014)... Oct. 2, 2014   West Pharmaceutical Services, Inc. ... in innovative solutions for injectable drug administration, announced today ... include a new site in Waterford, Ireland ... for insulin injector cartridges and other high-value packaging components, ... biotech customers. Once operational, this new site could bring ...
(Date:10/1/2014)... DUBLIN, Ohio , Oct. 1, 2014 ... to shareholders is now available. Interested parties can ... and how Cardinal Health is supporting the ... at http://cardinalhealth.com/annualreport . Photo- ... addition to summary financials and the chief ...
(Date:10/1/2014)... 1, 2014  ResMed (NYSE: RMD ), a ... company to design complete sleep apnea solutions specifically for women, ... importance of a good night,s sleep. The ... that feeling tired is just part of living a busy ... a critical pillar of health, essential to not only living ...
Breaking Medicine Technology:West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 2West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 3West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 4West Announces Plans for a New Pharmaceutical Component Manufacturing Plant in Ireland 5Cardinal Health 2014 Digital Report to Shareholders Now Available 2ResMed Launches Initiative to Help Women Get Better Sleep 2ResMed Launches Initiative to Help Women Get Better Sleep 3
(Date:10/2/2014)... Originally considered alternative food only ... increasingly popular with consumers. This has fuelled demand ... industry in Australia. According to IBISWorld industry ... has surged over the past five years, contributing ... level.” Over the five years through 2014-15, industry ...
(Date:10/2/2014)... Maureen Salamon HealthDay ... -- Middle-aged women with a neurotic personality style and ... Alzheimer,s disease, new research suggests. Tracking 800 women ... who were most anxious, jealous and moody -- which ... had double the risk of developing Alzheimer,s compared to ...
(Date:10/2/2014)... (HealthDay News) -- Children with autism are more sedentary ... of being more active, a small study suggests. ... children, some with autism and some without. Children with ... physical activity and 70 more minutes each day sitting ... autism scored lower on strength, but had similar body-mass ...
(Date:10/2/2014)... Amy Norton HealthDay Reporter WEDNESDAY, ... smelling the roses -- literally -- may face an increased risk ... In a study of over 3,000 older Americans, researchers found those ... peppermint were more than three times as likely to die in ... smell. In fact, anosmia -- the inability to distinguish odors ...
(Date:10/2/2014)... medical discovery by scientists at The University of Nottingham ... type of painkiller. , A drug resulting from the ... , would offer new hope to sufferers of chronic ... few effective painkillers are currently available. , The work, ... of Life Sciences, in collaboration with David Bates, Professor ...
Breaking Medicine News(10 mins):Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 2Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 3Health News:Organic Livestock and Poultry Farming in Australia Industry Market Research Report Now Available from IBISWorld 4Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 2Health News:Jealous, Moody Women May Face Higher Alzheimer's Risk, Study Says 3Health News:Kids With Autism Tend to Be Less Active, Study Says 2Health News:Could a Fading Sense of Smell Point to Earlier Death? 2Health News:Could a Fading Sense of Smell Point to Earlier Death? 3Health News:Medical discovery first step on path to new painkillers 2
... PhD, president of The J. David Gladstone Institutes, ... The award recognizes his leadership as Gladstone,s founding ... one of the world,s foremost independent research institutions, ... impact on disease prevention. Mahley will be ...
... ... regarding 2010 Shanghai, China Expo -- attracting attention from all walks of life. , ... Beijing (PRWEB) February 10, 2010 -- ... biggest World Expo in the history of world expositions. , , ,This special tour has ...
... women don,t know it is leading killer, survey finds , ... almost half of all American women still don,t know that ... new research finds. , Even more concerning, only slightly more ... they were having heart attack symptoms, according to the latest ...
... with Inflammatory Bowel Disease (IBD) are known to be at high ... of their disease but now new research by scientists at The ... to hospital during flare-ups are also at risk. The two ... affect about one in every 250 people in the UK. The ...
... ... to learn how to differentiate from competition and manage risk. , ... Lafayette, CO (PRWEB) February 10, 2010 -- Auto dealers will be able ... lead-generation, HR best practices and OSHA regulations at the Orlando NADA Convention and Expo 2010., , ...
... Poll Finds Voters Prefer Tobacco Tax to Other Tax Increases, Budget Cuts ... Utah ,s cigarette tax by $1 per pack would bring ... the state,s budget shortfall, while also reducing smoking and saving lives, according ... organizations.  In Utah, health advocates are calling on state leaders to increase ...
Cached Medicine News:Health News:Gladstone's Robert Mahley to receive Research!America advocacy award 2Health News:Jion Beijing Great Wall International Travel Agency Immediate Exposure to China Expo 2010 2Health News:Women's Heart Disease Awareness Still Lacking 2Health News:Women's Heart Disease Awareness Still Lacking 3Health News:Bowel disease link to blood clots 2Health News:Bowel disease link to blood clots 3Health News:KPA and TK Carsites offer HR, OSHA and Internet Marketing Workshops at the NADA Convention and Expo 2010 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $43.3 Million for Utah and Cut Youth Smoking 2Health News:New Report: $1 Cigarette Tax Increase Would Raise $43.3 Million for Utah and Cut Youth Smoking 3
It provides excellent illumination from an inexpensive platform and is mounted on the comfortable UltraLite headband....
It is a fiberoptic based intracranial monitoring systems for continuous monitoring of pressure....
... The Polaris system delivers the most ... effective and easy to use, this ... of precision measurement with unprecedented tracking ... active and passive tools, the Polaris ...
Penfield Dissector #2...
Medicine Products: