Navigation Links
ISTA Pharmaceuticals Initiates Phase 3 Clinical Program for REMURA™ in Dry Eye Disease
Date:9/16/2010

ndomized at a ratio of 1:1:1 to receive either bromfenac or placebo in both eyes twice daily and will be evaluated over the course of 42 days.  For both efficacy studies, the objective sign of conjunctival staining will be measured using the Lissamine Green test and subjective symptoms will be measured using the Ocular Surface Disease Index (OSDI). ISTA anticipates reporting results in the middle of 2011.  

The two remaining Phase 3 safety studies are the subject of additional SPAs currently under review by the FDA. To meet FDA guidance on drugs for chronic dosing, the Company expects to conduct both a six-month and a twelve-month safety study. ISTA anticipates it will initiate one or both of these safety studies later this year, subject to reaching agreement with the FDA on the SPAs.

ABOUT DRY EYE DISEASE

Dry eye occurs when there is an imbalance of tears that provides moisture and lubrication to the eye, which can result in pain, itching, redness, blurry vision, light sensitivity and/or a gritty sensation or feeling of sand in the eye.  Causes for dry eye include environmental conditions such as air conditioning, smoke and dust, aging and menopause, side-effects from antihistamines and birth control pills, Sjogren's syndrome, rheumatoid arthritis and structural problems with the eye lid's ability to close. Left untreated, dry eye can lead to abrasions on the surface of the eye and damage to the cornea. Current treatments include artificial tears and ointments, topical steroids, a topical immunomodulator that is the only approved prescription eye drop treatment and punctal occlusion (closing or plugging of tear drains).  

ABOUT BROMFENAC OPHTHALMIC SOLUTION

REMURA (bromfenac ophthalmic solution for dry eye) is a sterile, topical non-steroidal anti-inflammatory (NSAID) compound under investigation for use as an ophthalmic agent to alleviate the signs and symptoms of dry eye disease. Since 2
'/>"/>

SOURCE ISTA Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Forest Pharmaceuticals Agrees to Guilty Plea for Violating FDA Laws
2. AVANIR Pharmaceuticals to Present at the UBS Global Life Sciences Conference
3. FierceBiotech Names VentiRx Pharmaceuticals as One of the Fierce 15 Biotech Companies of 2010
4. Access Pharmaceuticals Launches MuGard Product Website
5. Amira Pharmaceuticals Named One of Most Promising Biotech Companies by FierceBiotechs Annual Fierce 15
6. FierceBiotech Designates Alder Biopharmaceuticals One of Top Private Biotechs, Member of the 2010 Fierce 15
7. ARCADIS Jane Staveley to Moderate Congressional Briefing on Pharmaceuticals in Drinking Water
8. Oramed Pharmaceuticals Announces Successful Results of a Novel Exploratory Clinical Study of its Flagship Oral Insulin Capsule
9. Isis Pharmaceuticals to Present at the UBS Global Life Sciences Conference
10. Anadys Pharmaceuticals to Present at Two Upcoming Investor Conferences
11. Merrimack Pharmaceuticals to Present at the 2010 Stifel Nicolaus Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... GENEVA, Ill. , Jan. 15, 2014 The ... a Medical Fitness Center by the Medical Fitness Association, ... centers to achieve their full potential. The Cadence Fitness ... in the western suburbs and second in the Chicagoland ...
(Date:1/15/2014)... , Jan. 15, 2014 Reportlinker.com announces ... available in its catalogue: ... Worldwide Analysis http://www.reportlinker.com/p01957812/Insulin-Pump-Market--Forecast-–-Worldwide-Analysis.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Equipment_and_Supply ... Insulin Pumps are ...
(Date:1/15/2014)... Quebec , Jan. 15, 2014  Valeant Pharmaceuticals International, ... announced that the applicable waiting period under the Hart-Scott-Rodino ... the previously announced tender offer by its indirect wholly-owned ... outstanding shares of common stock of Solta Medical, Inc. ...
Breaking Medicine Technology:Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... Monday,s massive, one-day, free medical clinic at the Ernest N. ... doctors and advanced practice nurses to volunteer, because travel problems ... some physicians and nurses from reaching New Orleans. ... in Hurricane Irene,s path," Dr. Rani Whitfield, a Baton Rouge ...
... DIEGO, Aug. 26, 2011 Cardium Therapeutics (NYSE ... Christopher J. Reinhard, Chairman and Chief Executive Officer, ... Investor Conference on Monday, August 29, 2011, at ... Newport Beach, California.  The slide presentation will be ...
Cached Medicine Technology:Urgent Call Is Issued for More Local Doctors and Nurses for Monday's Free Health Clinic 2Cardium to Present at Southern California Investor Conference 2
(Date:4/17/2014)... Meaningful long-term survival is possible for selected patients ... treated with cytoreductive surgery with Hyperthermic IntraPeritoneal Chemotherapy, ... physicians at Wake Forest Baptist Medical Center. , ... experience with cytoreductive surgery and HIPEC, said lead ... 20 years, worth of patient data shows that ...
(Date:4/17/2014)... per cent of Canadians surveyed said they would participate ... specific number of genetic conditions, only 80 per cent ... that would sequence their newborns, genomes.,Most newborns in North ... day or two of life in which a tiny ... tested for about five to 54 conditions, depending on ...
(Date:4/17/2014)... have called for more research to be carried ... in sub-Saharan Africa. In a paper in ... Stothard, working with colleagues in the department of ... in Cleveland Ohio, University of Cambridge and the ... the joint burden of HIV/AIDS and schistosomiasis of ...
(Date:4/16/2014)... ANTONIO, Texas (April 16, 2014) A team that includes ... Texas Health Science Center at San Antonio, Johns Hopkins University ... that helps a common fungus to infect the body. , ... diaper rashes and oral thrush, and is the most common ...
(Date:4/15/2014)... nearly half of all injuries aboard commercial freezer-trawlers and ... operating off the coast of Alaska, new research from ... and others aboard the two types of vessels could ... methods used in the study could help identify and ...
Breaking Medicine News(10 mins):Health News:20 years of data shows treatment technique improvement for advanced abdominal cancer 2Health News:Researcher looks at public perceptions around newborn testing 2Health News:Researcher looks at public perceptions around newborn testing 3Health News:More research called for into HIV and schistosomiasis coinfection in African children 2Health News:Changes in processing, handling could reduce commercial fishing injuries 2
... skilled negotiators when it comes to relationships and the ... of Gothenburg, Sweden. The thesis examines what children ... use. The results show that young children are skilled ... children learn, through play, which negotiation strategies are appropriate ...
... Findings worrisome because thyroid hormones play critical role in ... News) -- Exposure to flame-retardant chemicals may reduce a ... a critical role in fetal brain development, a new ... are used in a large number of consumer products, ...
... and Dora to market treats should be banned, researcher ... cartoon characters are influencing the taste preferences of very ... new study suggests. , Researchers found that the branding ... Dora the Explorer drives preschoolers to choose higher-calorie, less ...
... ... you might hope to want or need for the sunny weather to come! , ... London, UK (PRWEB) June 19, 2010 -- The summer is pretty much ... best. Fear not, for anyone stuck in London without so much as a grain of sand in ...
... ... Horizon Healthcare Services, Inc. to Put Evidence-Based Medicine into Practice with Via Oncology Pathways ... Pittsburgh ... will continue to improve as a result of wider application of Via Oncology™ Pathways, ...
... ... form of release and expression, and now it has been fine-tuned to deliver mental rejuvenation ... ... this world, it can be difficult for the average person to relax or even get ...
Cached Medicine News:Health News:Young children are skilled negotiators 2Health News:Flame Retardant May Up Risk of Thyroid Problems in Pregnancy 2Health News:Cartoon Characters Sell Kids on Unhealthy Foods 2Health News:Cartoon Characters Sell Kids on Unhealthy Foods 3Health News:Summer is Here - The Best Value Luxury Manicures, Spa Packages and Spa Waxing from Kuno Tierra, Mayfair Spa 2Health News:Hematology-Oncology Associates of Northern New Jersey (HOANNJ) Joins Effort to Improve Cancer Care with Via Oncology™ Pathways 2Health News:Hematology-Oncology Associates of Northern New Jersey (HOANNJ) Joins Effort to Improve Cancer Care with Via Oncology™ Pathways 3Health News:Reinvent your Mental State With Brainwave Entrainment Relaxation Music 2Health News:Reinvent your Mental State With Brainwave Entrainment Relaxation Music 3Health News:Reinvent your Mental State With Brainwave Entrainment Relaxation Music 4
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: