Navigation Links
ISTA Pharmaceuticals Announces Positive Results for Phase IIb Study of Ecabet Sodium
Date:1/22/2009

IRVINE, Calif., Jan. 22 /PRNewswire-FirstCall/ -- ISTA Pharmaceuticals, Inc. (Nasdaq: ISTA), today announced positive results from the Company's Phase IIb clinical study of ecabet sodium, which is being developed as a treatment for dry eye disease. Patients treated with ecabet sodium achieved a strong positive trend in the objective sign of Tear Film Break-Up Time (TFBUT) and a positive trend in the objective sign of quantity of tears produced (Schirmer Test). In contrast, there were no trends seen in the placebo group for either objective sign. In addition, there were no trends seen in either group in subjective symptoms as measured by the Ocular Surface Disease Index (OSDI) or patient's worst reported symptom. In Phase II tests where observations are not powered to show statistical significance, strong and positive trends are used as indicators of potential efficacy in subsequent Phase III studies.

"The Phase IIb results from this environmental study add further support to our belief that ecabet sodium has the ability to treat signs and symptoms of dry eye syndrome. Ecabet sodium may provide advantages over other products used to treat dry eye and those that are in development, as we believe ecabet sodium not only improves the quality of tears but also increases the quantity of tears," stated Vicente Anido Jr., Ph.D., President and Chief Executive Officer of ISTA Pharmaceuticals. "After reviewing the guidance from and our discussions with the FDA, we believe that by conducting two successful Phase III environmental clinical trials for improvement in signs and two successful Phase III controlled chamber clinical trials for the improvement of symptoms, we should receive marketing approval. In addition, we are expecting results from a Phase II clinical trial studying the potential of a lower strength of Xibrom to treat the signs and symptoms
'/>"/>

SOURCE ISTA Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. ISTA Pharmaceuticals New Drug Application for Bepreve(TM) Accepted for Review by U.S. Food and Drug Administration
2. Jazz Pharmaceuticals, Inc. Completes Enrollment in Second of Two Phase III Clinical Trials of Sodium Oxybate to Treat Fibromyalgia
3. AcelRx Pharmaceuticals Reports Positive Results from a Clinical Trial of Sublingual Sufentanil/Triazolam NanoTab(TM) Combination (ARX-03) in Treating Procedural Pain and Anxiety
4. Idenix Pharmaceuticals Initiates Proof-of-Concept Study of IDX184 for the Treatment of Hepatitis C Virus (HCV)
5. Solace Pharmaceuticals Initiates Phase IIa Trial of Glial Cell Modulator SLC022 in Post-Herpetic Neuralgia
6. Quark Pharmaceuticals Announces Dosing of the First Patient in Phase I/II Clinical Trial for Systemically Delivered siRNA Drug Candidate for Delayed Graft Function
7. Cylene Pharmaceuticals Initiates Phase I Trial With CX-4945 -Breakthrough First-in Class Inhibitor of CK2
8. Arena Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial of Type 2 Diabetes Drug Candidate in Partnership with Ortho-McNeil-Janssen Pharmaceuticals
9. Arena Pharmaceuticals Announces Preliminary Results of Phase 2b Clinical Trial of APD125 for the Treatment of Insomnia
10. Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology
11. Portola Pharmaceuticals Initiates Phase II Trial of Novel IV and Oral Anti-Platelet Drug in Non-Urgent Percutaneous Coronary Intervention
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... JORDAN, Utah , July 10, 2014  BC ... solutions, and MiE America , Inc., a leading ... have entered into a long-term agreement naming BC Technical ... the US. MiE and BC Technical ... strategic agreement to establish BC Technical as the service ...
(Date:7/10/2014)... July 10, 2014 CVS Caremark Corporation (NYSE: ... has approved a quarterly dividend of $0.275 (27.5 cents) per ... on August 1, 2014, to holders of record on July ... CVS Caremark is dedicated to helping people on their path ... the United States . Through the company,s ...
(Date:1/15/2014)... DUBLIN , Jan. 15, 2014  Research and Markets ... "Dental Consumables Market - Global Industry Analysis, Size, ... report to their offering. (Logo: ... products which are used on patients in order to ...
Breaking Medicine Technology:BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... LITTLE FALLS, N.J., March 3, 2011 Cantel Medical Corp. ... its second quarter ended January 31, 2011 on Wednesday, March ... to discuss the results at 11:00 AM ET. Participating in ... Krakauer, President and CEO; Seth R. Segel, Executive Vice President; ...
... ConvaTec Healthcare, a world-leading developer, manufacturer and marketer of ... announced that, recognizing favorable conditions in the credit markets, ... a portion of its senior secured term loans originally ... While the year-end audit process is ongoing, ConvaTec presently ...
Cached Medicine Technology:Cantel Medical Corp. to Hold Conference Call to Discuss Results for Its Second Quarter Ended January 31, 2011 2ConvaTec Healthcare Announces Plans to Refinance Secured Term Loans 2ConvaTec Healthcare Announces Plans to Refinance Secured Term Loans 3
(Date:7/14/2014)... Love Digits LLC has successfully launched ... The App brings ancient astrology to the modern dating ... compatibility using a five-star rating system. By entering their ... test their compatibility for love and marriage across seven ... five-star rating system generates a weighted average of the ...
(Date:7/14/2014)... Spine Team Texas continues to ... to treatment and recovery. Currently all physical therapists at ... training for certification in The McKenzie Method. Two therapists, ... extensive program. , “We require certification of our therapists ... better outcomes for spine pain patients,” said Mark Hood, ...
(Date:7/14/2014)... WA (PRWEB) July 14, 2014 ... solutions, today announced its new IBM i (AS/400, ... Software Vendors (ISVs). As security threats evolve and ... software providers struggle to modernize their applications and ... program now makes it easy for ISVs on ...
(Date:7/14/2014)... Crystal Dental has recently announced that ... has been made via LAD Solutions in in order to ... been made in order to draw in new patients that ... , Crystal Dental offers a variety of services for both ... Crystal Dental include cosmetic dentistry procedures such as porcelain veneers ...
(Date:7/13/2014)... July 14, 2014 Save the Date for ... Hospital in Jacksonville, FL , BOXWOODS & BowTies “A Modern ... , Who: The Women’s Board of Wolfson Children’s Hospital ... Show to continue their ongoing commitment to raising funds ... children. , What: The 2014 Art & Antiques Show ...
Breaking Medicine News(10 mins):Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 2Health News:Love Digits, Numerical Approach to Modern Love, Now Available on iTunes 3Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 2Health News:Spine Team Texas’ Physical Therapists Complete The McKenzie Method Training and Certification 3Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 2Health News:IBM i ISVs Can Now Easily Integrate Mobile-Based Two Factor Authentication to Increase Security of Solutions 3Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 2Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 3Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 4Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 5Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 6Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 7Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 8Health News:Save the Date for the 2014 Art & Antiques Show benefiting Wolfson Children's Hospital in Jacksonville, FL 9
... of Pennsylvania School of Veterinary Medicine have demonstrated ... attacks the cellular machinery, disrupts normal cellular function ... identified for the first time that mitochondria, the ... cellular fuel, are the target of tetrachlorodibenzodioxin, or ...
... insurance status are associated with survival rates among patients ... the December issue of Archives of OtolaryngologyHead & Neck ... U.S. men and women each year are diagnosed with ... background information in the article. For many years, total ...
... the industry,s technology leader in end-to-end bill cycle ... ... Workers, Compensation Payers, CONCORD, Calif., Dec. ... in providing catastrophic and complex,medical management services has entered ...
... DETROIT, Dec. 17 With much of the state experiencing,one ... more on,the horizon, Blue Cross Blue Shield of Michigan and ... mind and go slow,when clearing snow from driveways and sidewalks ... * Shoveling snow ...
... and Lab Accreditation ... ... Quality and Compliance Management Software, announced today that,it has donated over ... whose mission is to improve lives,worldwide through research, education, and services ...
... offers a critical appraisal of published research exploring the benefits of patients adhering to each of ... healthy eating habits , ... glucose monitoring , medication compliance ... healthful coping , ...
Cached Medicine News:Health News:Agent orange chemical, dioxin, attacks the mitochondria to cause cancer, says Penn research team 2Health News:Study examines factors associated with survival in advanced laryngeal cancer 2Health News:Paradigm Selects Jopari to Provide E-Billing Gateway for Customers 2Health News:Paradigm Selects Jopari to Provide E-Billing Gateway for Customers 3Health News:Blue Cross Blue Shield of Michigan Says Don't Let Snow Be a Pain: Ease into Clearing Sidewalks, Drives 2Health News:Blue Cross Blue Shield of Michigan Says Don't Let Snow Be a Pain: Ease into Clearing Sidewalks, Drives 3Health News:IQS Donates Quality Management Software to Family Health International 2Health News:IQS Donates Quality Management Software to Family Health International 3
... Borrelia (Lyme) test is an ... for the qualitative detection of ... and related Borrelia burgdorferi antibodies ... detected in serum as an ...
... Tests are qualitative enzyme immunoassays (EIA) for ... (IgG or IgM, respectively) in serum. Equivocal ... be supplemented with a standardized western blot ... to support a clinical diagnosis of B. ...
... dot-blot assay system combining microwell EIA and ... antigen set at a clinically meaningful cutoff ... detected using the same reagent system used ... antigens detected in Auto 4 detecting the ...
... The ImmunoWELL Cardiolipin Antibody (IgM) ... (EIA) for the quantitative detection ... in serum and is used ... the risk of thrombosis in ...
Medicine Products: