Navigation Links
ISIS Initiates Phase 1 Clinical Trial of ISIS-SOD1Rx in Patients With ALS
Date:3/5/2010

important study evaluating ISIS-SOD1Rx in people with familial ALS," said Merit Cudkowicz, M.D., Co-Chair of the Northeast ALS Consortium and a Professor of Neurology at the Massachusetts General Hospital of Harvard Medical School.

"It is evident that certain cases of familial ALS are related to mutant forms of SOD1.  Therefore, the selective inhibition of SOD1 production could provide a way to improve the outcomes of these patients with ALS," said Timothy Miller, M.D., Ph.D., Assistant Professor of Neurology at Washington University School of Medicine and Director of the Christopher Wells Hobler Laboratory for ALS Research at the Hope Center for Neurological Disorders.  "This is the first study to administer an inhibitor of SOD1 directly into the central nervous system.  Having been involved with Isis in the research and now the clinical development of ISIS-SOD1Rx, I am looking forward to co-chairing this study with Dr. Cudkowicz and the Northeast ALS Consortium."

"ISIS-SOD1Rx is our first antisense drug to enter clinical trials to treat a neurodegenerative disease and our first antisense drug to be administered directly into the central nervous system.  Based on our earlier preclinical studies, we believe that ISIS-SOD1Rx could offer an effective treatment for patients with familial ALS," said C. Frank Bennett, Ph.D., Senior Vice President of Research at Isis Pharmaceuticals.  "This study is the first step
'/>"/>

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Kinex Pharmaceuticals Initiates a Phase 2 Clinical Trial of KX2-391 in Patients with Prostate Cancer
2. QRxPharma Initiates Second Pivotal Phase 3 Study of MoxDuo(TM)IR Dual-Opioid(TM) for NDA Submission
3. Daiichi Sankyo Initiates Largest Single, Double-Blind, Randomized, Phase III Trial for Treatment and Prevention of Recurrent Venous Thromboembolism
4. Celsis Initiates Patent Infringement Action Against XenoTech and Sekisui
5. Romark Initiates Clinical Trial of Alinia for Treatment of Influenza
6. Conatus Pharmaceuticals Initiates Phase II Clinical Trial in Combination With Pegylated Interferon and Ribavirin for the Treatment of Hepatitis C Virus (HCV)
7. ChemoCentryx Initiates Clinical Trial of CCX168, A Novel Small Molecule C5aR Antagonist for the Treatment of Inflammatory and Autoimmune Diseases
8. Naurex Inc. Initiates Phase I Clinical Trial of its Novel Mechanism NMDA Modulator GLYX-13 in Treatment-Resistant Depression
9. Keryx Biopharmaceuticals, Inc. Initiates Phase 3 Registration Trial of KRX-0401 (Perifosine) for Treatment of Patients with Advanced Multiple Myeloma
10. ChemoCentryx Initiates Phase 2 Clinical Trial of CCX354 for the Treatment of Rheumatoid Arthritis
11. Sangart, Inc. Initiates Phase IIa Study of Oxygen Therapeutic Agent MP4OX in Severe Trauma Patients With Hemorrhagic Shock
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... 2014 Research and Markets ( ... "Investment Analysis of the US Medical Device ... http://photos.prnewswire.com/prnh/20130307/600769 ... device sector identifies the key trends and rationale ... and mergers and acquisitions. The study ...
(Date:12/22/2014)... Inc. (NASDAQ: CYBX ), a global leader in ... announced it will participate in the 33 rd  Annual ... San Francisco . Dan ... at 11:00 AM Pacific Time.  A live audio webcast of ... Relations link on the Cyberonics home page at www.cyberonics.com ...
(Date:12/22/2014)... Dec. 22, 2014 /PRNewswire/ -- RXi Pharmaceuticals Corporation (NASDAQ: ... on discovering, developing and commercializing innovative therapies addressing ... issued the following open letter to shareholders from ... Med. Sc. Dear RXi Shareholders, ... of inaccurate statements posted on certain social media ...
Breaking Medicine Technology:Investment Analysis of the US Medical Device Sector 2RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6
... Group, Inc. (NYSE: HGR ) announced today that it ... March 31, 2011, on Thursday, April 28, 2011. The ... the quarter ended March 31, 2011 on Wednesday, April 27, 2011 ... these results is scheduled to begin at 9:00 a.m., EDT, on ...
... (Pink Sheets: IMJX ), today officially reported ... highlighted the key business accomplishment during the past fiscal ... 2010 demonstrated significant improvement from 2009, with total sales ... all of 2010, both a significant improvement over the ...
Cached Medicine Technology:Hanger Orthopedic Group, Inc. Announces First Quarter 2011 Earnings Release Conference Call 2ImageXpres Posts OTC Markets 2010 Annual Report 2ImageXpres Posts OTC Markets 2010 Annual Report 3
(Date:12/25/2014)... 2014 Recently, BellasDress has ... its wedding dresses. BellasDress has chosen their best-selling lace ... choices for the holiday season. , Now, BellasDress.com ... wedding gowns here at discount prices. The business hopes ... its website. , “All our elegant products ...
(Date:12/25/2014)... When head lice hits a home or school, ... get rid of it while keeping it from taking over ... have the solution right in their neighborhood: Lice Troopers ... provides full spectrum head lice screening and treatment services to ... Key Biscayne, Brickell, Coconut Grove, Kendall, Pinecrest and South Miami. ...
(Date:12/25/2014)... 25, 2014 (HealthDay News) -- The risk of burns ... so you need to be extra cautious, an expert ... see a significant increase in patients coming in with ... Suffolk County Volunteer Firefighters Burn Center of Stony Brook ... be full of joy, but if not careful, could ...
(Date:12/25/2014)... Thompson HealthDay Reporter WEDNESDAY, ... in on a "fountain of youth" drug that can delay ... adults, a new study suggests. Seniors received a significant ... targets a genetic signaling pathway linked to aging and immune ... The experimental medication, a version of the drug rapamycin, ...
(Date:12/25/2014)... (PRWEB) December 25, 2014 “ SmileStix ” ... which features the latest and coolest mobile applications on the ... expert and host of NewsWatch, conducted the app review and ... to create personal stickers. , The old saying goes, “A ... lot of words that can describe a single image, because ...
Breaking Medicine News(10 mins):Health News:BellasDress.com’s Christmas Sale: Trendy Wedding Dresses With Big Discounts 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Don't Let Burns Mar Your Holidays 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 2Health News:Researchers Take 'First Baby Step' Toward Anti-Aging Drug 3Health News:An Application to Create Custom Stickers was Featured on NewsWatch Television on December 19, 2014 2
... strangulation game in 2005-2006 , , THURSDAY, Feb. 14 (HealthDay ... playing the "choking game" since 1995, a new government ... "pass out game," "scarf game," "space monkey" and other ... oneself or another with hands or some sort of ...
... Next Before Final Version is,Voted On, BETHESDA, Md., ... "national need" will include occupational,therapists if an agreement made ... AOTA staff worked fast and furiously to have the ... was able to have Representative Tom,Price of Georgia ask ...
... team of researchers was able to identify the location ... through analysis of genetic material (DNA) from members of ... from autosomal dominant juvenile cataract. The corresponding protein belongs ... molecules across cell mem-branes. Surprisingly, this genetic defect may ...
... , , THURSDAY, Feb. 14 (HealthDay News) -- A new ... found in the U.S.-banned insecticide DDT accelerates the growth ... in the open access journal Breast Cancer Research ... of a hormone that would otherwise help inhibit growth ...
... of the presidential nomination campaign, some candidates health care ... phrase socialized medicine has been used to attack health ... by the Harvard Opinion Research Program at the Harvard ... that Americans are split on whether a socialized medical ...
... available for all Minnesotans, MINNEAPOLIS, Feb. 14 ... such as a birthday or holiday as a "quit ... perfect day to,quit smoking for that special someone, and ... Services from ClearWay,Minnesota(SM)., Some romantic benefits of quitting, ...
Cached Medicine News:Health News:'Choking Game' Turned Deadly for 82 Youths 2Health News:'Choking Game' Turned Deadly for 82 Youths 3Health News:AOTA Gets Profession Addressed on House Floor in Federal Loan Repayment Bill 2Health News:New cataract gene discovered 2Health News:DDT Compound Speeds Breast Cancer Growth 2Health News:Poll finds Americans split by political party over views on socialized medicine 2Health News:Poll finds Americans split by political party over views on socialized medicine 3Health News:QUITPLAN(R) Services Can Help Make Valentine's Day Smoke-Free 2Health News:QUITPLAN(R) Services Can Help Make Valentine's Day Smoke-Free 3
... The new E300 Corneal ... diverse range of clinical procedures ... Refractive Surgery and Contact Lens ... compact cone design, the E300 ...
Egg-Shaped Bioceramic orbital implants insert easily into orbital socket and will not cling to surrounding tissue. Improved interconnectivity between pores enhances vascularization. Implants may be e...
... The S7 with Discrete Technology ... plus unmatched scaffolding. Proprietary Secure Technology ... proximal pillows that partially encapsulate the ... Discrete Technology is designed to minimize ...
Increased stent scaffolding at the proximal end gives optimal lumen support and 6F guide catheter compatibility and improved tracking offer excellent deliverability. Customized balloon lengths for ea...
Medicine Products: