Navigation Links
INCIVO® (Telaprevir) SVR Rates Unaffected by Ribavirin Dose Reduction in Treatment Naïve and Previously Treated Patients With Genotype-1 Chronic HCV
Date:4/18/2012

ng marketed under the brand name INCIVEK[TM].  Mitsubishi Tanabe Pharma has rights to commercialize telaprevir in Japan and certain Far East countries where it is being marketed as TELAVIC®.

Important Safety Information

Please see full Summary of Product Characteristics or visit http://www.ema.europa.eu for more details.

The overall safety profile of telaprevir is based on the Phase 2/3 clinical development programme. In clinical trials, the incidence of adverse events of at least moderate intensity was higher in the telaprevir group than in the placebo group (both groups receiving peginterferon alfa and ribavirin). The most frequently reported moderate adverse reactions (incidence ≥ 5.0%) were anaemia, rash, pruritus, nausea, and diarrhoea, and the most frequently reported severe adverse reactions (incidence ≥ 1.0%) were anaemia, rash, thrombocytopenia, lymphopenia, pruritus, and nausea.[10]

Rash events were reported in 55% of patients with a telaprevir based regimen and more than 90% of rashes were of mild or moderate severity. Severe rashes were reported with telaprevir combination treatment in 4.8% of patients. Rash led to discontinuation in 5.8% of patients. Anaemia was reported in 32.1% of patients and led to discontinuation in 2.8%.[10]

About HCV

HCV is a blood-borne infectious disease that affects the liver.[8,9] With an estimated 130-210 million people infected worldwide,[10] and three to four million people newly infected each year, HCV puts a significant burden on patients and society.[11] Estimations indicate that HCV caused more than 86,000 deaths and 1.2 million disability-adjusted life-years (DALYs) in the WHO European region in 2002.[12'/>"/>

SOURCE Janssen Pharmaceutica N.V
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. New Sub-Analysis Evaluates Outcomes Associated with Lower Intracranial Hemorrhage Rates for Pradaxa® (dabigatran etexilate mesylate) Versus Warfarin in the RE-LY® Trial
2. petMD.com Celebrates Heartworm Awareness Month with Five Heartworm Prevention Tips for Pet Owners
3. Global Fund Celebrates Efforts of Partners Chevron, The Coca-Cola Company, (RED) and PEPFAR at Capitol Hill Event
4. BioStorage Technologies Integrates Sample Preparation Services into European Operations
5. Talyst Celebrates Its 10th Anniversary
6. Elsevier Integrates its Clinical Decision Support Solutions Into PatientKeeper CPOE
7. China Sky One Medical Reiterates CEO Sick Leave and Announces Significant Middle Management Resignations
8. Mercy Jets Celebrates Heart Month With Charitable Donations
9. Soligenix Demonstrates Positive Proof of Concept with its Proprietary Vaccine Thermostabilization Technology
10. Pevions Therapeutic Candida Vaccine Generates Functional B Cell Memory in all Vaccinees
11. Boston Scientific Epic™ Stent Demonstrates Positive Clinical Outcomes in Orion Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... , May 23, 2013  Hadasit Bio-Holdings Ltd. (TASE: ... biotech companies, based on intellectual property developed and ... ,s foremost medical research center, today announced ... received significant funding from the Israeli Ministry of ... (OCS) to support product development and advance clinical ...
(Date:5/23/2013)... , May 23, 2013  Texas, premier physician ... deliver doctors the survival tools they need to provide ... in today,s health care marketplace. "I am ... save local practices," said Stephen L. Brotherton ... (TMA). " Texas doctors are determined ...
(Date:5/23/2013)... ALBUQUERQUE, N.M. , May 23, 2013  Net ... in the telemedicine market, announced today the company has ... a telemedicine staffing company based in Huntsville, ... agency that specializes in the staffing and recruitment of ... upon completion of the final agreement, which is expected ...
Breaking Medicine Technology:Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2TMA Launches Physician Services Organization for Patient Care 2TMA Launches Physician Services Organization for Patient Care 3TMA Launches Physician Services Organization for Patient Care 4Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 2Net Medical Xpress Announces Acquisition of Telemedicine Staffing Company 3
... Ill., Dec. 15, 2010 Hospira, Inc. (NYSE: ... company, today announced that it will host a conference call ... for 2011 on Wednesday, Feb. 2, 2011, at 8 a.m. ... and full-year 2010 results earlier that morning, before the U.S. ...
... Inc., a biotechnology company commercializing the next generation ... Antibody (RabMAb®) technology, today announced that the Company ... operating under contract with the National Cancer Institute ... (NIH) to develop several dozen rabbit monoclonal antibodies ...
Cached Medicine Technology:Epitomics Signs Antibody Development Agreement With the National Cancer Institute 2
(Date:5/23/2013)... May 23, 2013 If you are ... irritable bowel syndrome (IBS), the food spread this Memorial ... fun. , “While hot dogs and ice cream have ... warm weather months, IBS sufferers often feel the painful ... MD, a gastroenterologist with Lourdes Medical Associates. , IBS ...
(Date:5/23/2013)... UT (PRWEB) May 23, 2013 ... a comprehensive radiology learning environment for all resident ... lessons and assessments, transforms the learning experience from ... curriculum. , “Until RADPrimer 3.0, RADPrimer ... to none,” comments Dr. B.J. Manaster, Professor of ...
(Date:5/23/2013)... a woman harried by hot flashes says she,s having ... online in Menopause , the journal of The ... tests that what these women say about their memory ... that hot flashes were related to memory problems, and ... was a relationship between hot flashes and what women ...
(Date:5/23/2013)... to its destruction inside a cell, a cancer-promoting ... thwart the development of tumor-suppressing microRNAs (miRNAs) before ... publication at Nature . , Under conditions ... epidermal growth factor receptor (EGFR) gums up the ... scientists at The University of Texas MD Anderson ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 Transvaginal ... Bard, Inc., continue to move forward in a federal ... of West Virginia, Bernstein Liebhard LLP reports. In ... a request by C.R. Bard to seal emails that ... secrets and other confidential, proprietary information about its suppliers. ...
Breaking Medicine News(10 mins):Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 2Health News:Sensitive Stomach? Lourdes Gastroenterologist Advises IBS Sufferers to Think Twice About What They Eat This Holiday Weekend 3Health News:RADPrimer 3.0 Introduces Comprehensive Radiology Training Curriculum 2Health News:When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs 2Health News:When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs 3Health News:Transvaginal Mesh Lawsuits Move Forward, as Bernstein Liebhard LLP Notes New Order in Federal C.R. Bard Mesh Implant Lawsuits 2Health News:Transvaginal Mesh Lawsuits Move Forward, as Bernstein Liebhard LLP Notes New Order in Federal C.R. Bard Mesh Implant Lawsuits 3
... Oct. 7 (HealthDay News) -- Men develop type 2 diabetes ... finding helps explain why men have higher rates of diabetes ... analyzed data from 51,920 men and 43,137 women in Scotland ... was 31.83 in men and 33.69 in women. This difference ...
... (HealthDay News) -- Women with polycystic ovary syndrome (PCOS), an ... to have parents with some form of heart disease, according ... between PCOS and other family medical conditions, we might be ... an earlier stage," the study,s lead author, Michael Davies, an ...
... Goodwin HealthDay Reporter , FRIDAY, Oct. 7 (HealthDay ... babies, with differences from typically developing infants seen in their ... Researchers said the findings may offer new clues about the ... the children also have a larger brain. Boys ...
... consumers take heed: that high-calorie energy drink or soda ... according to a double-blind, placebo-controlled study that examined responses ... predict how he or she will respond to other ... of other more serious drugs of abuse, such as ...
... Ore. Modern medicine,s ability to save lives through organ ... prevent the human body from rejecting the transplanted organ. ... sometimes serious. A group of researchers led by scientists ... that may be causing many of those side effects. And ...
... Oct. 7 (HealthDay News) -- Nearly your entire brain is ... to a new study. The finding that many more ... to win games, such as rock-paper-scissors, makes sense in terms ... functions to maximize the chance of survival and reproduction, so ...
Cached Medicine News:Health News:Boys With Autism May Grow Faster as Babies 2Health News:Boys With Autism May Grow Faster as Babies 3Health News:Jonesing for java: Could caffeine use predict risk for cocaine abuse? 2Health News:Study uncovers why anti-rejection drugs for transplant patients cause hypertension 2
...
Malis Curette, bayonet, titanium handle, stainless steel shaft, working distance 102 mm, length 203 mm....
Cobb Curettes, reverse angled, 11"....
Castroviejo "HM" Micro Needle Holder with Tungsten-Carbide Inserts, with catch. Serrated....
Medicine Products: