Navigation Links
IDRI Develops Novel Tuberculosis Vaccine, New Study in Science Reports
Date:10/15/2010

SEATTLE, Oct. 16 /PRNewswire-USNewswire/ -- The Infectious Disease Research Institute (IDRI) announces it has developed a new tuberculosis (TB) vaccine that protects against TB including drug-resistant strains of the disease in animal studies. The results of these studies are published in Science Translational Medicine today.

Drug-resistant tuberculosis is a major global public health concern. According to the World Health Organization, approximately 9 million people are infected with TB, and close to half a million are resistant to multiple drugs that once effectively treated the disease. Two million people die of TB each year.

Though a childhood vaccine for tuberculosis, BCG, has been widely used for decades, its protection wanes over time, and new virulent forms of the disease are spreading. Control activities are limited without new vaccines, immunotherapeutics, and drugs to protect against these killer strains of TB.

IDRI's TB vaccine enhances and extends BCG and protects against drug-resistant strains through its unique combination of a molecule containing four tuberculosis proteins with a synthetic adjuvant, also developed at IDRI.

Dr. Rhea Coler, Vice President of Preclinical Biology and one of the study's Principal Investigators, explains, "Combining proteins in a vaccine is important because tuberculosis bacilli are variable, and no single protein will be effective against all strains."  In addition, because of human genetic diversity, individuals will respond differently to different proteins. A combination of proteins, such as exist in natural tuberculosis bacteria, increases the vaccine's efficacy.

The vaccine is now being developed for clinical testing in humans.

About IDRI – Translating science into global health solutions

IDRI is a Seattle-based not-for-profit organization committed to applying innovative science to the research and development of products to prevent, detect, and treat infectious diseases of poverty. By integrating capabilities—including preclinical vaccinology, manufacturing, and clinical trials—IDRI strives to create an efficient pathway bringing scientific innovation from the lab to the people who need it most.

For more information, go to www.idri.org  


'/>"/>
SOURCE Infectious Disease Research Institute (IDRI)
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Diplomat Specialty Pharmacy Develops and Launches Best-In-Class Electronic Navigator (eNAV(TM)) Patient Care System
2. Nventa Develops Proprietary Vaccine Adjuvant
3. Bad News to Bad Bugs: Northern Antibiotics Develops Novel Polymyxins With Reduced Toxicity
4. Siemens Corporate Research Develops RAPID2 System for Fast Discovery of Discriminative Pathogen Signatures
5. Binghamton Research Group Develops New Cancer Treatment
6. Saft Develops Super-Phosphate(TM) Technology for Rigorous Defense Applications
7. Panel of Osteoarthritis Experts Develops Optimal Profile of Exogenous Hyaluronic Acid
8. HDT Develops Robotic Arm Technology for DARPAs Revolutionizing Prosthetics 2009 Program
9. Solos Endoscopy, Inc. Develops Relay Lense Adapter System For MammoView® Product Line
10. PharmAthene Develops Thermostable Lyophilized rPA Anthrax Vaccine Under a Challenge Grant From the National Institutes of Health
11. Varian Medical Systems Develops New X-Ray Tube for Use in Security Scanning Systems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... Research and Markets has announced the addition ... Demand Forecast to 2022" report to their offering. ... , , The ... and it is expected to grow at a CAGR of 5.5% during ... faster growth during the forecast period, a CAGR of 8.8% in the ...
(Date:12/2/2016)... , Dec. 2, 2016 Quantum Radiology,s Mobile ... expert radiologist interpretation directly to women at the workplace, ... corporations, such as Delta Air Lines and SunTrust Bank, ... as a component of wellness initiatives. "I ... SunTrust. It enables them to have a mammogram without ...
(Date:12/2/2016)... 2016 In the first ever attempt to ... derived from C. sativa, the Hebrew University in Jerusalem, ... Federico II , the Universita` del Piemonte Orientale and ... integrated and unified inventory of phytocannabinoids of different botanical ... the remarkable chemical and structural diversity of phytocannabinoids. As ...
Breaking Medicine Technology:
(Date:12/2/2016)... CA (PRWEB) , ... December 02, 2016 , ... For over twenty-four years, Doctors ... basis to help personal injury victims find high quality medical care. When the company ... Angeles area. Fast forward to present day and the now ten-page directory features a ...
(Date:12/2/2016)... ... 02, 2016 , ... Center for Autism and Related Disorders (CARD) Portland today ... spectrum disorder (ASD) and other developmental disabilities. The group, which is being launched with ... caregivers the opportunity to share stories and advice, seek help, and continue their education ...
(Date:12/2/2016)... ... December 02, 2016 , ... ... of two ostomy patients, standing as living proof that attitude and determination can ... diseases and issues that spike around the holidays. This campaign will offer patients ...
(Date:12/2/2016)... Wilmington, Delaware (PRWEB) , ... December 02, 2016 ... ... has released a new version of its SaaS LIMS, CloudLIMS Lite. CloudLIMS Lite ... from sample entry through labeling, storing, shipping and disposal. The new version is ...
(Date:12/2/2016)... ... ... Rijuven Corp launches rejiva ( http://www.rejiva.com ), a unique wearable technology that ... technology on the market can deliver all that rejiva can. , “Rejiva promotes relaxation ... health than the usual heart rate and steps taken”, adds Evens Augustin, CEO of ...
Breaking Medicine News(10 mins):