Navigation Links
IBM Research and Institute of Bioengineering and Nanotechnology Discover Breakthrough for Breast Cancer Drug Delivery
Date:11/1/2013

a targeted location directly at the tumor site over weeks instead of days. Once the drug has been delivered, the hydrogel biodegrades naturally and passes through the body.

"Drawing from our experience in materials innovation for electronics technology, we are now applying these techniques to the quest for improved health," said Dr. James Hedrick, Advanced Organic Materials Scientist, IBM Research – Almaden. "This hydrogel can help deliver drugs over an extended period of time without causing a significant immune response, effectively sending its contents directly to the tumor without harming healthy surrounding cells."

In animal studies done by Singapore's IBN, testing demonstrated improved results when the antibody was paired and delivered with the hydrogel, even at low concentration, than on its own.

  • Tumor Size: Over the course of 28 days, the tumor shrank 77% when paired with the hydrogel via subcutaneous injection at the tumor site as opposed to 0% without it by intravenous injection. 
  • Treatment Frequency: When paired with the hydrogel and injected subcutaneously at a site far away from the tumor, the treatment frequency was reduced from 4 to 1 while maintaining a similar therapeutic effect. This is when compared to just the antibody solution formulation injected intravenously. 
  • Weight: The ability to target and deliver the drug directly at the tumor site allowed for only the infected cells to be eradicated, leaving healthy cells alone. This resulted in stable to moderate weight gain during the study instead of massive weight loss traditionally associated with cancer drug treatments.
  • Non-Toxic: Since the hydrogel is non-toxic, it demonstrated high biocompatibility as evidenced by no cellular inflammation with minimal immune system response while degrading naturally and passing through the body
    '/>"/>

SOURCE IBM
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Research by ClinMet Scientific Founder and Colleagues Point to Enzyme that Restores Function in Diabetic Kidney Disease
2. PRA Staff Named Finalists in Clinical Researcher of the Year Competition
3. McCord Research Appoints Wound Care Education Expert
4. Neurology Devices Market is Expected to Reach USD 13.6 Billion Globally in 2019: Transparency Market Research
5. Medical Imaging Equipment Market is Expected to Reach USD 35.35 Billion Globally in 2019: Transparency Market Research
6. Philanthropic Grants, Product Launches, Promising Partnerships, and Customer Satisfaction Rankings - Research Report on CVS Caremark, Walgreens, McKesson, AmerisourceBergen, and Cardinal Health
7. Life Technologies Awards Digital PCR Innovation Grants to Five Research Labs
8. Kaiser Permanente Researchers Honored for Drug Therapy Study
9. InCube Labs Enters into an Agreement with the Engineering Research Center for Revolutionizing Metallic Biomaterials
10. Healthcare Sector Announced Clinical Data Presentation, Upcoming Financial Release Schedules and Updates on New Drug Applications - Research Report on Alexion, Pacira, pSivida, Momenta and Impax
11. Biocartis Presents the Successful use of Idylla[TM] for the Detection of the BRAF Mutation Status in Tumour Samples at the International AACR Congress (American Association for Cancer Research) in Boston
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... July 30, 2014   Medical Equipment Solutions, Corp. ... awarded a Department of Defense (US Army) contract valued ... a mobile MRI diagnostic machine and technical support staffing. ... through the Small Business Administration (SBA), Medical Equipment is ... with the latest medical diagnostic equipment. The SBA 8-A ...
(Date:7/30/2014)... , July 30, 2014   Epic Sciences, ... that designs and develops novel diagnostics to personalize ... announced today the completion of a $30 million ... new investors RusnanoMedInvest (RMI) and Arcus Ventures, existing ... Venture Investments, as well as undisclosed individual investors. ...
(Date:7/30/2014)... July 30, 2014 Company ... programming expertise to big data, aerospace and defense, ... eInfochips, a leading engineering R&D services company, today ... NVIDIA GPU-powered solutions for aerospace and defense ... (HPC), industrial , and visual ...
Breaking Medicine Technology:Medical Equipment Solutions Corp. Awarded $2 Million contract To Service DoD 2Epic Sciences Announces Series C Financing to Advance Essential Cancer Diagnostics for Personalized Medicine 2Epic Sciences Announces Series C Financing to Advance Essential Cancer Diagnostics for Personalized Medicine 3eInfochips to Develop NVIDIA GPU-powered Solutions for Aerospace and Defense, Medical Imaging, HPC and Visual Computing 2
... , , SOLON, Ohio, Dec. 16 ... of next generation technologies and a principal subcontractor for ... led development of new anthropromorphic arm technology that will ... and hand, including a sense of touch. , ...
... 16 A new application developed by American ... pharmaceuticals has increased health plan staff productivity and the number ... diagnostic imaging benefit management and technology company with health plan ... of WellPoint, Inc. (NYSE: WLP ), adapted the ...
Cached Medicine Technology:HDT Develops Robotic Arm Technology for DARPA's Revolutionizing Prosthetics 2009 Program 2American Imaging Management's New Specialty Drug Program Delivers Immediate Results 2American Imaging Management's New Specialty Drug Program Delivers Immediate Results 3American Imaging Management's New Specialty Drug Program Delivers Immediate Results 4
(Date:7/30/2014)... 30, 2014We have pills to ease pain, to cure infection, ... to enhance our sexual and athletic prowess. Why do pills ... we benefit from taking fewer pills? This provocative topic is ... and Fantasy of Pills in Modern Medicine ," published in ... peer-reviewed publication from Mary Ann Liebert, Inc., publishers. The article ...
(Date:7/30/2014)... Today, Gen. Arthur T. Dean, Chairman ... (CADCA) , the nation’s leading substance abuse prevention organization, ... New York Times Editorial Board’s call for marijuana ... , “CADCA is disappointed in the New York Times ... marijuana legalization. The move is shortsighted and completely disregards ...
(Date:7/30/2014)... 2014 (HealthDay News) -- Medical costs for chronic obstructive ... than $32 billion each year, according to new research ... The yearly financial toll of COPD (which includes ... estimated $49 billion by 2020. "For the first ... provide state public health practitioners with estimates of the ...
(Date:7/30/2014)... The Europe Phytochemicals & plant extracts market ... market in Europe with analysis and forecast of revenue. ... estimated to grow from around 710.18$ million in 2012 ... 8.4%, for the given period. , Browse through the ... report, to get an idea of the in-depth analysis ...
(Date:7/30/2014)... could help doctors decide which bladder cancer patients would ... according to a study* published in the British ... The University of Manchester, funded by the Medical Research ... levels of a protein, called ,HIF-1α, were more likely ... carbon dioxide gas and nicotinamide tablets at the ...
Breaking Medicine News(10 mins):Health News:CADCA Responds to New York Times Editorial Board's Call for Marijuana Legalization 2Health News:Annual COPD Costs To Hit $49 Billion by 2020: CDC 2Health News:Europe Phytochemicals & Plant Extracts (Nutraceuticals) Market is Expected to Reach $1,150.64 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Phytochemicals & Plant Extracts (Nutraceuticals) Market is Expected to Reach $1,150.64 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Phytochemicals & Plant Extracts (Nutraceuticals) Market is Expected to Reach $1,150.64 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Europe Phytochemicals & Plant Extracts (Nutraceuticals) Market is Expected to Reach $1,150.64 Million in 2018 - New Report by MicroMarket Monitor 5Health News:Scientists pinpoint bladder cancer patients who could benefit from 'tumor-softening' treatment 2
... team of researchers at the John Hopkins Hospital in the US ... the PSA to detect prostate cancer.// ,The new test ... a simple blood test. ,Prostate cancer, the most ... of medicine. Physicians are unsure how to find it and when ...
... Thirteen year olds can perform cardiopulmonary resuscitation (CPR) as ... today. The authors suggest that children as young as ... chest compressions. ,Bystander CPR more than doubles ... arrest. Chest compressions are thought to be the most ...
... At least one-third of the time, the symptoms of ... in children, it can be difficult //to distinguish bipolar ... 2007 issue of the Harvard Mental Health Letter. ... the adult cycle of distinct mood episodes of mania ...
... are similar or better than those of whites when differences ... published in the American Heart Journal, Reuters reports. ... Rogers Memorial Veterans Hospital and colleagues studied the care and ... who were treated at five VA hospitals. ...
... Ahmed Obaid, Under-Secretary General and Executive Director of the ... Regional Director of UNFPA have// pressed the need for ... the highest maternal mortality rate in the world. More ... improve the health of the women and children. ...
... of the HIV eradication potential of a bone marrow transplant ... concluded that// eradication is unlikely utilising this method. ... reduce HIV to 'undetectable' levels in the blood, but they ... of our own cells. Although scientists have been working on ...
Cached Medicine News:Health News:New blood test to detect prostate cancer 2Health News:Priority Needs to Be Given to Maternal Health in Afghanistan 2Health News:HIV Eradication Unlikely Following Bone Marrow Transplantation 2Health News:HIV Eradication Unlikely Following Bone Marrow Transplantation 3
... Unparalleled Comfort Pick one of our pipettors ... the trigger and ejector positionsright where they should ... are ergonomically designed to help avoid repetitive stress ... Productivity In The Palm Of Your Hand ...
... multichannel has the same innovative ... model. The same universal handle ... five single channel tip cone ... recharge and storage stand with ...
... The Research pro Electronic Pipette is ideal ... laboratory. Its easy-to-follow display, ergonomically-placed operating buttons, ... dispensing, reverse pipetting and diluting make this ... simple functions of a manual pipette without ...
... Comfort Pick one of our pipettors up ... trigger and ejector positionsright where they should beeven ... ergonomically designed to help avoid repetitive stress injuries ... In The Palm Of Your Hand Start ...
Medicine Products: