Hyperion Therapeutics Announces Enrollment of First Patient in Phase 1/2 Clinical Trial of GT4P in Patients With Urea Cycle... (d synthetase (AS)) and a pre-prodrug of ...)

HOME >> MEDICINE >> TECHNOLOGY

Hyperion Therapeutics Announces Enrollment of First Patient in Phase 1/2 Clinical Trial of GT4P in Patients With Urea Cycle Disorders

Date:10/23/2007

d synthetase (AS)), and a pre-prodrug of phenylacetate (PAA).

About Urea Cycle Disorder

A urea cycle disorder is an inherited, inborn error of metabolism present in an estimated 1 in 10,000 live births in the U.S. Patients with UCDs lack or are deficient in one of the key enzymes that comprise the urea cycle, the body's primary vehicle for removing ammonia, a potent neurotoxin, from the bloodstream. The age of onset of UCDs is typically in the neonatal period, but onset can occur at any age, depending on the severity of the disorder. Left untreated, UCDs can cause dangerously heightened levels of ammonia in the bloodstream (hyperammonemia) resulting in brain damage, coma, and/or death.

There is no cure for UCDs. Adherence to a low-protein diet is a key component to chronic disease management. Current therapies include arginine supplementation, which drives functional parts of the urea cycle, essential amino acid supplementation, replacement of urea cycle intermediates, and administration of nitrogen-scavenging drugs including BUPHENYL(R) for chronic management and AMMONUL(R) (sodium phenylacetate and sodium benzoate) disease Injection 10%/10% for episodes of acute hyperammonemia. Orthotopic liver transplantation may also be considered for patients with severe disease.

About Hyperion Therapeutics

Hyperion Therapeutics is a specialty therapeutics company focused on becoming a global leader in gastrointestinal (GI) and hepatology therapeutic programs and products that address underserved patient populations or unmet medical needs. The company has assembled a seasoned executive team with extensive industry experience developing and commercializing specialty pharmaceutical products. Hyperion is headquartered in South San Francisco, CA. For additional information, visit: http://www.hyperiontx.com.

About AMMONUL(R)

AMMONUL(R) is indicated as adjunctive therapy for the treatment
'/>"/>

SOURCE Hyperion Therapeutics, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4
Related medicine technology :

1. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
2. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
3. CV Therapeutics Identifies Potential Anti-Diabetic Mechanism of Action for Ranexa
4. GTC Biotherapeutics to Webcast Corporate Presentation at the C.E. Unterberg, Towbin Emerging Growth Life Opportunities Conference
5. Fat Kills Cancer: Turning Stem Cells from Fat Tissue into Personalized, Cancer-Targeted Therapeutics
6. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
7. Clinical Trial Suggests Bone Marrow Stem Cells Are Useful for Spinal Cord Injury; PrimeCell Therapeutics Provided Pre-Clinical Study
8. Pieris Progresses Development of its Proprietary Biotherapeutics Platform: Successful Demonstration of Dual Targeting With Duocalin(R) Technology
9. Opexa Therapeutics Reports Positive Top-line Data in Phase I/II Extension Trial with Tovaxin for Multiple Sclerosis
10. Orexigen Therapeutics to Present Data on Contrave Impact on Visceral Fat and Insulin Resistance at American Diabetes Association 67th Scientific Sessions in Chicago June 23
11. Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer

Post Your Comments:

(Date:6/19/2013)... , June 19, 2013 The Physician-Patient Alliance for ... fatigue. The need to urgently address this issue ... Sentinel Event Alert #50 , "Medical device alarm safety in ... between January 2008 and June 2012, there were 98 alarm ... in death (82%) , 13 resulted in permanent loss ...

(Date:6/19/2013)... , June 19, 2013 Decision Resources, ... firms for pharmaceutical and healthcare issues, finds that, ... of surveyed U.S. and European rheumatologists cite a ... attributes that most influences their prescribing decisions. Over ... European rheumatologists, respectively, rank the percentage of patients ...

(Date:6/19/2013)... , June 19, 2013 BD Biosciences, a ... BDX ), a leading global medical technology company, today announced ... , the latest in its line of high-performance research flow ... delivers high-performance multicolor analysis with the most compact footprint in ... cm) and a height of 30" (76.2 cm). Recognizing that ...

Breaking Medicine Technology:Three Lessons Learned to Reduce Alarm Fatigue and Improve Alarm Management and Patient Safety in Hospitals 2 Three Lessons Learned to Reduce Alarm Fatigue and Improve Alarm Management and Patient Safety in Hospitals 3 U.S. and European Rheumatologists Agree That a Therapy's Induction of Remission is One of the Attributes That Most Influences Their Prescribing Decisions in Rheumatoid Arthritis 2 New BD Biosciences Flow Cytometry Cell Analyzer Enables Complex Multicolor Experiments in Disease Research 2

[0] Three Lessons Learned to Reduce Alarm Fatigue and Improve Alarm Management and Patient Safety in Hospitals [0] U.S. and European Rheumatologists Agree That a Therapy's Induction of Remission is One of the Attributes That Most Influences Their Prescribing Decisions in Rheumatoid Arthritis [0] New BD Biosciences Flow Cytometry Cell Analyzer Enables Complex Multicolor Experiments in Disease Research

... Sept. 26, 2011 Not for release, publication ... South Africa, Japan or any jurisdiction where to do so would constitute ... September 2011CASH OFFER BY ALERE AS ... WHOLLY-OWNED SUBSIDIARY OF ALERE INC. ("ALERE") FOR ...

... The MedTech Conference opens today in Washington, D.C. ... and healthcare reform. More than 1,700 industry stakeholders from ... the leading annual medical device and diagnostics conference. ... Optics and Chairman of the Advanced Medical Technology Association ...

Alere Inc. Statement Amending Acceptance Condition to Axis-Shield Offer AdvaMed2011: The MedTech Conference Opens with Dialogues on Finance, Competitiveness, Harmonization, Entrepreneurship, Compliance and Health Reform One Year Later

(Date:6/19/2013)... PREFERRED Therapy Providers, Inc. (PREFERRED) has announced ... offer a new Medicare Advantage Plan for PREFERRED’s provider ... Mohave, Arizona counties. The agreement takes effect in two ... 2013 and Maricopa and Pima counties will become effective ... company of WellCare of Arizona has Medicare Advantage plans ...

(Date:6/19/2013)... Scottsdale, AZ (PRWEB) June 19, 2013 Guests ... feel healthy, wealthy and wise even if they don’t go ... that does require some early thought. , ... pockets when they take advantage of the pet-friendly Scottsdale Paradise ... Percent Package . With at least 14 days advance notice, ...

(Date:6/19/2013)... MO (PRWEB) June 19, 2013 ... partnered with ARAMARK Healthcare Technologies to help Pacific ... plan with savings of more than 17 percent ... maintenance service expenditures. , “Driving economies of scale ... medical equipment management challenges facing multi-site providers,” said ...

(Date:6/19/2013)... polio has been pushed to the brink of extinction ... of the big questions which a Bristol academic addresses in ... Professor of Medicine at the University of Bristol, has produced ... Paralysed with fear: the story of polio explores the experiences ... history of the disease. , According to a ...

(Date:6/19/2013)... The former internist for the St. ... now serves as director of prevention and wellness at ... own personal encounter with a metabolic syndrome diagnosis and ... Knives , that he credits with sparking the paradigm-shift ... medical practice. , “The average medical student gets 30 ...

Breaking Medicine News(10 mins):Health News:PREFERRED Therapy Providers, Inc. and WellCare of Arizona Finalize Their Agreement to Offer Medicare Advantage Plan to PREFERRED's Arizona Provider Network 2 Health News:Plan Ahead and Save Big With New Deal From Residence Inn Scottsdale Paradise Valley 2 Health News:Plan Ahead and Save Big With New Deal From Residence Inn Scottsdale Paradise Valley 3 Health News:Plan Ahead and Save Big With New Deal From Residence Inn Scottsdale Paradise Valley 4 Health News:Amerinet Partners with ARAMARK Healthcare Technologies to Help Pacific Medical Centers Save 17 Percent and Better Manage System-Wide Equipment Program 2 Health News:Paralysed with fear: The story of polio 2 Health News:Plant-based Nutrition is Key to Health Transformation of St. Luke’s Hospital Director of Prevention and Wellness 2 Health News:Plant-based Nutrition is Key to Health Transformation of St. Luke’s Hospital Director of Prevention and Wellness 3

[0] PREFERRED Therapy Providers, Inc. and WellCare of Arizona Finalize Their Agreement to Offer Medicare Advantage Plan to PREFERRED's Arizona Provider Network [0] Plan Ahead and Save Big With New Deal From Residence Inn Scottsdale Paradise Valley [0] Amerinet Partners with ARAMARK Healthcare Technologies to Help Pacific Medical Centers Save 17 Percent and Better Manage System-Wide Equipment Program [0] Paralysed with fear: The story of polio [0] Plant-based Nutrition is Key to Health Transformation of St. Luke’s Hospital Director of Prevention and Wellness

... commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is ... led by researchers at the San Francisco VA Medical Center. ... were several adverse side effects,” says lead author Thomas Neylan, ... “People with symptoms of PTSD should probably stay away from ...

... as those with asthma ,Los Angeles, Dec. 1, ... Southern California. Now, researchers// at the University of Southern ... regions suffered as much as those with asthma. ... issue of the American Journal of Respiratory and Critical ...

... heard of the illustrious mathematician and physicist, Albert Einstein, whose ... did you know that Albert Einstein suffered a learning disability// ... Einstein also had a problem with Maths in school. And, ... Mathematician, it is undoubtedly, the will to surmount odds as ...

... transplant? ,“There is no clear answer at this ... for lung transplantation// were written in 1998. They were based ... W. Smith, a surgery resident and research fellow at the ... (LTX) was first performed in 1983, it has been a ...

... Americans has fallen drastically, and the rate of decline has ... new analysis of data// from the National Long-Term Care Survey ... National Academy of Sciences, has revealed that the severe disability ... percent in 1982 to 19 percent in 2004/2005. ...

... Women who undertake a long-term weight training program ... that allows physiologists //to understand why weight training ... ,A study published in the December issue ... looked at different forms of growth hormone, used ...

Cached Medicine News:Health News:Common PTSD Drug is No More Effective Than Placebo 2 Health News:Southern California Wildfires Pose Health Risks to Children 2 Health News:Equal Opportunity for the Disabled 2 Health News:Elderly Lung Transplant Patients More Likely to Survive 2 Health News:Elderly Lung Transplant Patients More Likely to Survive 3 Health News:Disability Factor Among Older Americans Shows Improvement 2 Health News:Varying Weight Training Intensity Ups Growth Hormone in Women 2

Common PTSD Drug is No More Effective Than Placebo Southern California Wildfires Pose Health Risks to Children Equal Opportunity for the Disabled Elderly Lung Transplant Patients More Likely to Survive Disability Factor Among Older Americans Shows Improvement Varying Weight Training Intensity Ups Growth Hormone in Women

... PROXIMATE PLUS MD Skin Stapler is a ... deliver rectangular, stainless steel staples for routine ... Skin Stapler is supplied sterile and preloaded ... ,PROXIMATE Skin Staplers place single staples ...

... reloadable articulating (22° and 45° in both ... for resection, transection and anastomosis for open ... places two triple-staggered rows of staples and ... between. The instrument is designed for multiple ...

... delivers two staggered rows of titanium staples ... instrument is available in two sizes to ... a 30mm staple line while the 60mm ... ,The PROXIMATE Vascular Linear Stapler delivers three ...

Single Use Reloadable Stapler with Titanium Staples., ,The Auto Suture™ PREMIUM MULTIFIRE TA™ stapler has applications in abdominal, gynecological, pediatric and thoracic surgical proced...

Medicine Products:

PROXIMATE PLUS MD Skin Stapler GIA™ Universal 12 mm (Single Use Instrument)PROXIMATE TX Reloadable Linear Staplers PREMIUM MULTIFIRE TA™ (Single Use Reloadable Stapler with Titanium Staples)