Navigation Links
Human Genome Sciences and GlaxoSmithKline Announce Positive Phase 3 Study Results for BENLYSTA(TM) in Systemic Lupus Erythematosus
Date:7/19/2009

primary efficacy endpoint of superiority versus placebo at Week 52. A clinically and statistically significant improvement was shown in patient response rate for belimumab plus standard of care, vs. placebo plus standard of care: 57.6% for 10 mg/kg belimumab, 51.7% for 1 mg/kg belimumab, and 43.6% for placebo (p=0.0006 and p=0.011 for 10 mg/kg and 1 mg/kg belimumab, respectively vs. placebo). Patient response was defined by an improvement in SELENA SLEDAI score of 4 points or greater, no clinically significant BILAG worsening, and no clinically significant worsening in Physician's Global Assessment. Results for each individual component of the patient response rate were consistent with the overall improvement shown for the primary endpoint. -- Results for prespecified major secondary efficacy endpoints were: -- A significantly greater percentage of patients receiving belimumab achieved a reduction in SELENA SLEDAI score of at least 4 points by Week 52, with 58.3% for 10 mg/kg belimumab, 53.% for 1 mg/kg belimumab, and 46.0% for placebo (p=0.0024 and p=0.019 for 10 mg/kg and 1 mg/kg belimumab, respectively vs. placebo). -- Improvement in Physician's Global Assessment (PGA) at Week 24 was greatest in the belimumab 10 mg/kg treatment group versus placebo (p=0.0003 for 10 mg/kg and p=0.27 for 1 mg/kg belimumab, respectively) with improvement observed within 4-8 weeks. -- A higher percentage of patients in both belimumab treatment groups, versus placebo, had their average prednisone dose reduced by at least 25% from baseline to 7.5 mg per day or less during the last 12 weeks of study (p=0.053 for 10 mg/kg and p=0.025 for 1 mg/kg belimum
'/>"/>
SOURCE Human Genome Sciences, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Lpath Demonstrates Strong Safety Profile of Lead Drug Candidate, Sphingomab(TM), in Non-Human Primates
3. Enrollment Begins on Human PK Study for Medidur(TM) FA
4. Human Genome Sciences Completes Enrollment of First Phase 3 Albuferon(R) Trial Ahead of Schedule
5. Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006
6. Lpath Demonstrates Preclinical Efficacy of Lpathomab(TM) and Initiates Humanization Process
7. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
8. Dr. Roger Kenneth Hershline PhD MD, CEO of Global Humanceuticals, Inc. Donates New HIV Drug
9. Study Shows Plasma-Derived Human Thrombin Equivalent to Bovine Thrombin in Achieving Hemostasis in Surgery
10. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
11. Flexible Medical Systems Raises $1.2M Seed Investment for Initial Human Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... YORK , August 21, 2014 ... Israeli subsidiary, BreedIT Ltd., the exclusive worldwide license ... software for plant breeders and researchers, today is ... a joint venture with Seach Ltd, a leading ... formed to research and develop new breeds of ...
(Date:8/21/2014)... 2014  ACI Clinical ( www.aciclinical.com ) announces ... Committees. Using this solution, trial sponsors ... standard costs and receive the same expertise that ... services. Leveraging a decade of DMC ... development, statistical programming and meeting facilitation), ACI analyzed ...
(Date:8/21/2014)...  Henry Schein, Inc. (NASDAQ: HSIC ), the ... office-based dental, animal health and medical practitioners, announced today that ... , September 4, 2014 – Baird 2014 Healthcare ... p.m. ET , September 8, 2014 – ... , NY at 1:25 p.m. ET Henry ...
Breaking Medicine Technology:BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 4ACI Clinical: Innovation and Savings in Data Safety Monitoring Committees 2Henry Schein To Present At Two Investor Conferences In September 2
... Pharmaceuticals, Inc. (Nasdaq: TRBN ) today announced financial ... Sept. 30, 2009. , (Logo: http://www.newscom.com/cgi-bin/prnh/20090320/TRUBIONLOGO ) , ... , Revenue for the third quarter and ... and $12.8 million, respectively, compared with $3.8 million and ...
... SADDLE RIVER, N.J., Nov. 5 PDI, Inc. (Nasdaq: PDII), ... to U.S. pharmaceutical companies, today reported financial and operational results ... Commenting on today,s announcement, Nancy Lurker, Chief Executive Officer of ... were lower than last year by approximately 14%. Higher ...
Cached Medicine Technology:Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 2Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 3Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 4Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 5Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 6Trubion Pharmaceuticals, Inc. Reports Third Quarter and Nine Months 2009 Financial Results 7PDI Reports 2009 Third Quarter Financial Results 2PDI Reports 2009 Third Quarter Financial Results 3PDI Reports 2009 Third Quarter Financial Results 4PDI Reports 2009 Third Quarter Financial Results 5PDI Reports 2009 Third Quarter Financial Results 6PDI Reports 2009 Third Quarter Financial Results 7PDI Reports 2009 Third Quarter Financial Results 8PDI Reports 2009 Third Quarter Financial Results 9PDI Reports 2009 Third Quarter Financial Results 10PDI Reports 2009 Third Quarter Financial Results 11
(Date:8/21/2014)... According to a new market report published ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 ... at USD 236.1 million in 2011 and is estimated ... 2018 at a CAGR of 6.3% from 2012 to ... http://www.transparencymarketresearch.com/fundus-cameras.html . , Fundus cameras market growth in ...
(Date:8/21/2014)... 21, 2014 It's a terrible thing when ... to a serious substance abuse issue. When that happens to ... action is getting reliable help from the qualified substance abuse ... facility isn’t always easy for those young adults living in ... significant addiction issue. , Thankfully there is a new ...
(Date:8/21/2014)... The worlds of personal care and yoga are ... grab free products. BaliniSports will be shipping ... with all qualifying purchases for a limited time. “The ... apparel is simply perfect,” said Ada Hung, founder and ... brands is intended to give people in the yoga ...
(Date:8/21/2014)... Rockville, Maryland (PRWEB) August 21, 2014 ... developed with guidance from Lockton Companies and builds ... the industry’s only cellular glucometer, combined with Accountable ... and robust data analytic capabilities and adds a ... provider care, including eye exams, provider visits, HbA1c ...
(Date:8/21/2014)... Tibet has long been a desired ... kingdom. Prayers flags whip in the wind against ... rumble of chanting monks fill the otherwise silent temples. ... access to Tibet is challenging due to high elevation ... prove to be daunting for even the most experienced ...
Breaking Medicine News(10 mins):Health News:Fundus Cameras Market: Product Type- Mydriatic, Non-Mydriatic, Hybrid and ROP Cameras; End Users- Hospitals, Ophthalmology Clinics and Ophthalmic & Optometrist Offices 2Health News:Young Adults in Pompano Beach, FL Are Finding Success With Innovative New Helpline 2Health News:Tom's of Maine Partner up with BaliniSports Yoga Apparel 2Health News:Accountable Health Expands Diabetes Management Solutions to Address Gaps in Provider Care 2Health News:Accountable Health Expands Diabetes Management Solutions to Address Gaps in Provider Care 3
... HealthDay Reporter , MONDAY, Aug. 30 (HealthDay News) -- ... summer months, new research shows. In a study using ... from Brigham and Women,s Hospital in Boston found that new ... spring and summer compared to colder times of the year. ...
... women during visits to family planning clinics whether their ... a type of intimate-partner violence called reproductive coercion ... continue to experience such pressures, according to a new ... School of Medicine. Young women who recently experienced ...
... A new study from Hasbro Children,s Hospital finds visits ... team sports have increased dramatically over a 10-year period, ... football. The number of sports-related concussions is highest in ... is significant and rising. The study is published in ...
... Alan Mozes HealthDay Reporter , SUNDAY, Aug. ... low-dose omega-3 fatty acid supplements don,t appear to gain ... research cautions. In fact, neither low doses of ... found in fish oil, nor of alpha-linolenic acid (ALA), ...
... Dr. Hernn Makse, professor of physics at The City College ... way that information and infectious diseases proliferate across complex networks. ... contrary to conventional wisdom, persons with the most connections are ... where someone is located in a network," said Professor Makse ...
... Austin,s new Health Information Technology program has received $2.7 ... and Education for Health Information Technology (PURE HIT) consortium ... of Health and Human Services Office of the National ... graduated its first class of 54 students this summer. ...
Cached Medicine News:Health News:Multiple Sclerosis Changes With the Seasons 2Health News:Multiple Sclerosis Changes With the Seasons 3Health News:Study finds asking about pregnancy coercion and intimate-partner violence can reduce their incidence 2Health News:Study finds asking about pregnancy coercion and intimate-partner violence can reduce their incidence 3Health News:Concussions in young athletes on the rise 2Health News:Concussions in young athletes on the rise 3Health News:Low-Dose Omega-3 Fatty Acids Don't Protect Heart Patients 2Health News:Low-Dose Omega-3 Fatty Acids Don't Protect Heart Patients 3Health News:Location determines social network influence, CCNY-led team finds 2Health News:Location determines social network influence, CCNY-led team finds 3Health News:Health IT program at the University of Texas at Austin receives $2.7 million in federal funding 2Health News:Health IT program at the University of Texas at Austin receives $2.7 million in federal funding 3
...
...
Conforms to the convexity of the lens providing easier access to anterior capsule. Reduces pontential of corneal touch. 25G x 5/8in (.50 x 16mm)...
... Unique product designed for LASIK surgery ... Designed to irrigate the corneal interface ... easy insertion under the flap and ... ports provide multi-directional irrigation. Two 25G ...
Medicine Products: