Navigation Links
Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives
Date:5/28/2008

on-small cell lung cancer

in 2009.

New Targets Initiative to Feed Early-Stage Pipeline

HGS has a rich heritage of scientific discovery that has produced a vast intellectual property estate and a library of thousands of therapeutic and diagnostic targets. Over the past couple of years, HGS has conducted a careful review and selected approximately 50 targets for further research and potential development, with the goal of filing new IND's in 2010-2011.

HGS plans to develop the selected targets through co-development or research collaborations, as well as through its own internal research, including the application of antibody development technology from collaborators such as Cambridge Antibody Technologies and Xencor.

DARAPLADIB ADVANCING TO PHASE 3 TRIALS FOR THE TREATMENT OF ATHEROSCLEROSIS

Darapladib, a small-molecule inhibitor of Lp-PLA2, was discovered by GSK based on HGS technology. HGS will receive a 10% royalty on worldwide sales of darapladib if it is commercialized, and also has a 20% co-promotion option in North America and Europe.

In April 2008, GSK announced that it intends to advance darapladib to Phase 3 clinical trials as a potential treatment for atherosclerosis and will shortly start discussions with regulators regarding the structure of the darapladib Phase 3 program. Darapladib has the potential to be an important treatment for atherosclerosis.

At the American College of Cardiology's 57th Annual Scientific Session in March, GSK presented data from a randomized Phase 2 dose-ranging trial of darapladib in patients with coronary heart disease (CHD). The study showed that darapladib produced sustained, dose-dependent inhibition of plasma lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in patients receiving intensive atorvastatin (cholesterol-lowering) therapy. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques and identified in clinical trials as an independ
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine technology :

1. Pulmo BioTech Announces Details of the Methodology for its Phase I Human Trials
2. St. Jude Finds Dancing Hair Cells Are Key to Humans Acute Hearing
3. Increases in West Nile Virus Replikin Concentrations Precede Increases in the Number of Human Cases
4. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
5. Quantum Immunologics, Inc. and the South Alabama Medical Science Foundation Announce an Early Clinical Evaluation of a Novel Immuno-therapeutic Vaccine for Treating Advanced Human Breast Carcinomas
6. First Human Implant of New Archus Orthopedics Facet Replacement System
7. Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
8. Tepha Announces First Human Usage of Medical Devices Derived from New Class of Resorbable Polymers
9. Data Show SuperGens MP-470 is Safe in Humans
10. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
11. CardioMind Launches First-in-Human Trial of Small Vessel, Drug-Eluting Stent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/1/2015)... MOUNTAIN VIEW, Calif. , May 1, 2015 /PRNewswire/ ... the United States launch of ... an integrated, fast and easy system for exosome collection ... International Society for Extracellular Vesicles ("ISEV") Annual Meeting, April ... , D.C.  Both products are intended for research use ...
(Date:5/1/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/pjbxjd/us_aco_it ... ACO IT Spending Outlook 2018" report to their ... lives covered by ACO would grow at a CAGR ... ACO IT spending has been studied on three main ... spending on services. Our research provides current market estimation ...
(Date:5/1/2015)... May 1, 2015 Braeburn Pharmaceuticals ... current therapeutic focus beyond addiction and pain ... disorders. Braeburn has acquired an implantable, six-month ... risperidone for treatment of schizophrenia from Endo ... global rights to other potential applications of ...
Breaking Medicine Technology:New Products for Exosome Isolation to mRNA Purification 2United States ACO IT Spending Outlook 2014-2018 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4
(Date:5/2/2015)... (PRWEB) May 03, 2015 As one ... of the prestigious Safety and Health Achievement and Recognition ... honored to be chosen by the Illinois Department of ... has achieved and maintained SHARP certification by the Occupational ... 2006, as Essentra has continued to meet or exceed ...
(Date:5/2/2015)... ProText Kinetic 2 is a set of typography creation ... ProText Kinetic 2 features 40 animation presets that ... . Easily create interactive text videos without having to ... 2. , Using ProText Kinetic is as easy as drag ... in the FCPX timeline. Playback the default animation and ...
(Date:5/2/2015)... East Liverpool, Ohio (PRWEB) May 02, 2015 ... of East Liverpool City Hospital (ELCH) gathered to celebrate ... direction of River Valley Health Partners (RVHP), had zero ... and zero urinary catheter associated infections. ELCH was also ... , The management team at ELCH credited the ...
(Date:5/2/2015)... With the success that Veatch Dental Consulting has had over ... and Alex Shields to the team. With Neida and Alex ... combined experience working with dentists to ensure their success. , ... years. She was certified as dental assistant from Texas ... and showing the importance of oral hygiene to patients, Neida ...
(Date:5/1/2015)... 01, 2015 Jusuru International has been ... successful repositioning of its flagship nutritional supplement, Liquid BioCell™ ... a new name, new logo, new packaging, new products, ... are designed to identify and promote programs that serve ... , “DSA congratulates Jusuru International for their outstanding accomplishments ...
Breaking Medicine News(10 mins):Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 2Health News:Essentra Specialty Tapes is Selected to Host Gov. Rauner and the Workers' Memorial Day Celebration 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:Veatch Dental Consulting Services Welcomes New Team Members 2Health News:Jusuru International Receives 2015 DSA Ethos Award 2Health News:Jusuru International Receives 2015 DSA Ethos Award 3Health News:Jusuru International Receives 2015 DSA Ethos Award 4Health News:Jusuru International Receives 2015 DSA Ethos Award 5
... April 30 Approximately sixty-five state and local public ... responsibility for confirmatory testing of Human Influenza A H1N1 ... week. Previously, all swine flu specimens had to be ... testing, which identifies specimens to the strain level.The rRT-PCR ...
... Justice grant creates federal-state-local partnership to help fight ... A sweeping $1.1 million U.S. Justice Dept. grant ... prosecution agency to help combat domestic violence and ... State,s Attorney,s Appellate Prosecutor,s office has hired two ...
... the pancreas, invagination of the pancreas into the small ... according to researchers at the Jefferson Pancreas, Biliary and ... Journal of the American College of Surgeons . ... gold standard for studies. , Removing the head of ...
... agreement on principles for Getting Health IT Right under ... Today the Markle Foundation hosts a forum to ... information technology (IT) under the American Recovery and Reinvestment ... will meet with government and policy experts to talk ...
... Golf Car and a Day on the Field of a ... April 30 On Saturday, May 2 nd ... at the Los Angeles Equestrian Center for the 11th Annual ... support of raising funds for cancer research. Fiesta, a ...
... Podcast from Perot Systems on the Role of Information Technology in Improving HealthcarePLANO, Texas, ... Dr. Harry Greenspun, executive vice president and chief, ... Guest: Dr. Nathaniel Hupert, Director of The Preparedness Modeling Unit, ... Centers for Disease Control and Prevention (CDC) and, ...
Cached Medicine News:Health News:Public Health Laboratories To Assume Primary Responsibility for Confirmatory Testing of Swine Flu 2Health News:New Illinois Prosecution Unit Helps Protect Women Against Violence 2Health News:Type of connection procedure after pancreatic surgery influenced rate of pancreatic fistula 2Health News:Meaningful Investment of $19 Billion on Health Information Technology 2Health News:Meaningful Investment of $19 Billion on Health Information Technology 3Health News:Celebrities, Horses, Music and History Will Unite for 2009 'Fiesta of the Spanish Horse' Cancer Research Benefit 2Health News:Looking Forward: The Use of Health IT in Crisis 2Health News:Looking Forward: The Use of Health IT in Crisis 3Health News:Looking Forward: The Use of Health IT in Crisis 4
... Mid-Calf Boot is a shorter and ... designed for second degree ankle sprains, ... protection. The Bledsoe EZ Set Mid-Calf ... motion from 20 degrees of dorsi-flexion ...
... Diabetic Boot features a fully enclosed thick, ... unique auto-molding innersole which embeds into a ... aluminum shelled walking boot. This unique Automold™ ... distribute body weight across the entire bottom ...
... and Cronin, Inc. is ... Patient Footwear, Orthopedic Softgoods, ... Products. Our products are ... and available in the ...
DarcoGel™ Upper chamber is foam filled, conforms to calf; gel-filled lower chamber molds to the malleoli for a custom fit. Freeze the removable liner for cold therapy. One size. Fits left or ri...
Medicine Products: