Navigation Links
Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives
Date:5/28/2008

imminent in a Phase 1 clinical trial of HGS1029 in patients with advanced solid tumors. Preclinical studies of HGS1029 in combination with the Company's TRAIL receptor antibodies demonstrated synergistic activity against a number of cancer types. HGS1029 has also shown significant anti-tumor activity alone and in combination with other agents in a broad range of cancers. HGS plans to develop its TRAIL receptor antibodies and IAP inhibitors in combination with one another and in combination with other therapeutic agents.

HGS reacquired the rights to its TRAIL receptor antibodies from GSK in April 2008 in return for a reduction in royalties due to HGS if Syncria(R) (albiglutide) is commercialized. The fees and milestone payments due to HGS under the original Syncria agreement, some of which have already been received, could amount to as much as $183 million and remain unchanged in the amended agreement.

HGS views the oncology portfolio as a key driver of future growth beyond the launch of the Company's late-stage products. Reacquiring the rights to HGS-ETR1 and HGS-ETR2 (lexatumumab) gives HGS the opportunity to drive and advance this important program more aggressively by enabling the exploration of new alliances with a more optimal structure that could bring development expertise and resources, commercial leadership, near-term milestone payments and cost-sharing. HGS is also capable financially and organizationally of taking the TRAIL receptor antibodies forward on its own, thus retaining 100% of the value.

Key milestones of advancement for the HGS oncology portfolio:

-- Potential new alliance(s) for TRAIL receptor antibodies.

-- Initiation of HGS1029 Phase 1 trial in solid tumors imminent.

-- Initiation of HGS-ETR1 randomized trial in hepatocellular cancer.

-- Data expected from HGS-ETR1 Phase 2 trial in multiple myeloma in the

third quarter of 2008.

-- Data expected from HGS-ETR1 Phase 2 trial in n
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine technology :

1. Pulmo BioTech Announces Details of the Methodology for its Phase I Human Trials
2. St. Jude Finds Dancing Hair Cells Are Key to Humans Acute Hearing
3. Increases in West Nile Virus Replikin Concentrations Precede Increases in the Number of Human Cases
4. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
5. Quantum Immunologics, Inc. and the South Alabama Medical Science Foundation Announce an Early Clinical Evaluation of a Novel Immuno-therapeutic Vaccine for Treating Advanced Human Breast Carcinomas
6. First Human Implant of New Archus Orthopedics Facet Replacement System
7. Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
8. Tepha Announces First Human Usage of Medical Devices Derived from New Class of Resorbable Polymers
9. Data Show SuperGens MP-470 is Safe in Humans
10. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
11. CardioMind Launches First-in-Human Trial of Small Vessel, Drug-Eluting Stent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... 2014 Amgen (NASDAQ: AMGN ) ... 2014. Key results include: , Total revenues increased ... sales growth driven by strong performance across the portfolio, ... Prolia ® (denosumab) and XGEVA ® (denosumab). ... driven by higher revenues and a significant increase in ...
(Date:7/29/2014)... July 29, 2014 Regado Biosciences, Inc. (Nasdaq: ... the Phase 3 clinical development of Revolixys™ Kit (previously ... system, today announced that it will hold a conference ... 2014, at 8:30 a.m. EDT to discuss its second ... Interested participants and investors may access the conference call ...
(Date:7/29/2014)...  EnteroMedics Inc. (NASDAQ: ETRM ), the ... obesity, metabolic diseases and other gastrointestinal disorders, today announced ... August 7, 2014 at 11:00 AM Eastern Time to ... 30, 2014 and to provide a business update. ... conference call may be accessed by dialing (877) 280-7473 ...
Breaking Medicine Technology:Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 2Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 3Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 4Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 5Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 6Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 7Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 8Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 9Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 10Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 11Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 12Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 13Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 14Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 15Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 16Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 17Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 18Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 19Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 20Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 21Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 22Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 23Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 24Amgen's Second Quarter 2014 Revenues Increased 11 Percent To $5.2 Billion And Adjusted Earnings Per Share (EPS) Increased 25 Percent To $2.37 25Regado Biosciences to Provide Second Quarter 2014 Financial Results and Corporate Highlights 2Regado Biosciences to Provide Second Quarter 2014 Financial Results and Corporate Highlights 3EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 2EnteroMedics to Host Second Quarter 2014 Financial Results and Business Update Conference Call 3
... 27, 2011 A milestone in lupus research was met this ... Research (ALR) held its 8th annual New York City Walk ... Park was matched by the enthusiasm of the nearly 3000 walkers ... by NYC master of ceremonies, My9 news anchor Brenda Blackmon, ALR ...
... 27, 2011   FHSSA counts its partnership initiative ... known as the Foundation for Hospices in Sub-Saharan ... between US hospice programs and organizations providing care ... assistance, support and friendship.  They are working collaboratively ...
Cached Medicine Technology:Alliance for Lupus NYC Walk With Us to Cure Lupus First Lupus Walk In History To Raise $1-Million 2FHSSA Launches New Campaign to Partner US Hospices with Programs in Sub-Saharan Africa 2
(Date:7/29/2014)... Daily Gossip reveals in its review that ... that will permanently eliminate all the symptoms associated to this ... will banish symptoms such as mild hearing loss, as well ... patients will be gone forever. , The method will lead ... of this program says that at the end of the ...
(Date:7/29/2014)... 29, 2014 Daily Gossip indicates in its ... tips to gain beautiful and clear skin in just 30 ... see these positive results even sooner than that. The new ... who used this step by step program, too. , ... for years. Mike battled this condition for a decade and ...
(Date:7/29/2014)... combat injuries threatening more than one limb, reconstructive surgical ... safety and effectiveness in avoiding amputation, reports a paper ... Reconstructive Surgery , the official medical journal of ... , Experience with multiple limb salvage procedures in solders ... with no increase in complications compared to single-flap techniques, ...
(Date:7/29/2014)... TUESDAY, July 29, 2014 (HealthDay News) -- Chlorine helps ... swimmers more likely to develop eye infections, doctors say. ... eyes as well as blurry vision, said Dr. Sampson ... Center in New Jersey. It,s important to understand ... pools washes away the outer film layer of the ...
(Date:7/29/2014)... According to a July 22, 2014 ... “From Kim’s Butt to Angelina’s Lips: The Plastic Surgery ... the celebrity feature most requested by women seeking cosmetic ... Jennifer Lawrence’s nose, and Angelina Jolie’s ... data collected by an online community focused on plastic ...
Breaking Medicine News(10 mins):Health News:Tinnitus Miracle Review Exposes the Only Holistic System for Tinnitus Cure 2Health News:Acne No More Review Reveals Most Effective Acne Cure Program 2Health News:Good outcomes with multiple limb salvage after severe combat injuries, reports Plastic and Reconstructive Surgery 2Health News:Protect Your Eyes When Hitting the Pool 2Health News:Celebrity Plastic Surgery: Kim Kardashian’s Butt Tops the List of Celebrity Plastic Surgery Requests 2
... Chains; 6 Receive an ,F, NEW YORK, Aug. ... your children fat? A year-long study of children,s meals ... sit-down,chain restaurants, according to the authors of the new ... and Matt Goulding calculated,calories, fat (trans- and saturated), and ...
... services for cardiovascular ... ... leader in disease prevention, announced today that the City of Tempe,Arizona ... have asthma or diabetes and are covered under the City,s PPO,Medical ...
... Current strategies can,t beat this growing challenge, researchers say ... of treating tuberculosis are failing in countries with high ... say researchers who analyzed World Health Organization data from ... countries with high rates of MDR-TB, patients are nearly ...
... that builds on healthcare reform proposal, WASHINGTON, ... today by Senators Max Baucus (D-MT) and Kent ... officer of the Blue,Cross and Blue Shield Association ... Senators Baucus and Conrad for introducing legislation that,would ...
... higher risk; doctors urged to expand education efforts , , ... at higher risk for HIV/AIDS, and doctors need to ... tested for HIV. , That,s the new recommendation released ... (ACOG). , "Rates of infection among African Americans ...
... available in <A HREF="http://www.eurekalert.org/pub_releases_ml/2008-08/aaft-t080108.php,">German . , , If someone ... change, but they don,t immediately pull off one of ... leg. With some molecules, however, the situation is quite ... seven atoms. In a charged state, the atoms arrange ...
Cached Medicine News:Health News:America's Worst Restaurants for Kids Revealed 2Health News:America's Worst Restaurants for Kids Revealed 3Health News:America's Worst Restaurants for Kids Revealed 4Health News:America's Worst Restaurants for Kids Revealed 5Health News:City of Tempe, Arizona Extends Contract with U.S. Preventive Medicine for Employee Health Management Program 2Health News:City of Tempe, Arizona Extends Contract with U.S. Preventive Medicine for Employee Health Management Program 3Health News:Drug Resistance Is Slowing Global Fight Against TB 2Health News:BCBSA: Time Is Right for Comparative Effectiveness Research Institute 2Health News:Ob/Gyn Group Urges Routine HIV Tests for All Women 2Health News:Nano sculptures in gold 2Health News:Nano sculptures in gold 3Health News:Nano sculptures in gold 4
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Kleinert-Kutz Single Skin Hook, Large...
Designated most popular model or size....
Medicine Products: