Navigation Links
Human Genome Sciences Reports Progress With Late-Stage Products and New Initiatives
Date:5/28/2008

y control disease symptoms and progression. HGS market research suggests that LymphoStat-B, assuming Phase 3 trials are successful, could play a major role in the treatment of SLE, with a differentiated profile for use in chronic therapy.

Key milestones leading to a potential U.S. launch of LymphoStat-B in 2010:

-- Complete enrollment and initial dosing in BLISS-76, one of two Phase 3

trials of LymphoStat-B in patients with active SLE, by the end of

summer 2008.

-- First Phase 3 data available by mid-2009 (from BLISS-52), the second

Phase 3 trial of LymphoStat-B in patients with active SLE.

-- All Phase 3 data available in fall 2009.

-- Planned filing of a Biologics License Application (BLA) in early 2010.

HGS today also announced that HGS and GSK have agreed to initiate a Phase 2 trial of LymphoStat-B for use in the treatment of multiple sclerosis (MS). Patients with MS continue to have unmet medical needs despite the treatments currently available. The scientific rationale for testing LymphoStat-B in MS is strong, since the drug acts by inhibiting the activity of BLyS(TM), a protein discovered by HGS, which is found at elevated levels in MS lesions and is associated with the MS disease process. In addition, the results of a Phase 2 trial of rituximab provided clinical validation for B-cell modulation in the treatment of relapsing-remitting MS.

ABthrax(TM) (raxibacumab), a human monoclonal antibody that prevents anthrax toxins from entering and killing cells, for the treatment of anthrax disease

HGS reported in December 2007 that the results of two animal studies demonstrated the life-saving potential of ABthrax in the treatment of inhalation anthrax. The results show that a single dose of ABthrax, administered without the use of antibiotics, improved survival rates by up to 64 percent when administered after animals were already showing symptoms of anthrax disease as a result of
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine technology :

1. Pulmo BioTech Announces Details of the Methodology for its Phase I Human Trials
2. St. Jude Finds Dancing Hair Cells Are Key to Humans Acute Hearing
3. Increases in West Nile Virus Replikin Concentrations Precede Increases in the Number of Human Cases
4. Video: The Journal, Human Genetics, Publishes Results Supporting Interleukin Genetics Heart Health Test
5. Quantum Immunologics, Inc. and the South Alabama Medical Science Foundation Announce an Early Clinical Evaluation of a Novel Immuno-therapeutic Vaccine for Treating Advanced Human Breast Carcinomas
6. First Human Implant of New Archus Orthopedics Facet Replacement System
7. Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
8. Tepha Announces First Human Usage of Medical Devices Derived from New Class of Resorbable Polymers
9. Data Show SuperGens MP-470 is Safe in Humans
10. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
11. CardioMind Launches First-in-Human Trial of Small Vessel, Drug-Eluting Stent
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... May 22, 2015 /CNW/ - More than fifty years ago, ... morning sickness in expectant mothers. Tragically, Thalidomide caused serious and ... Support has been provided to survivors over ... Canada in 1991 and settlements from ... a legal obligation to provide support, we have a clear ...
(Date:5/22/2015)... YORK , May 22, 2015 ... of the $13 billion global cardiac rhythm management ... Information.  Kalorama found that Medtronic, St. Jude Medical, ... command 80% of this market segment. The healthcare ... Device Markets , uses 2015 as a base ...
(Date:5/22/2015)... , May 22, 2015  RegeneRx Biopharmaceuticals, Inc. ... a peer-reviewed publication of the results of the ... (RegeneRx,s preservative-free eye drops) for the treatment of ... environment (CAE ® ) model.  The exploratory study ... which were previously disseminated by the Company in ...
Breaking Medicine Technology:Statement from Minister Ambrose on Thalidomide 2Statement from Minister Ambrose on Thalidomide 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 2Kalorama: Top Companies Dominate Cardiac Defibrillator Market 3Kalorama: Top Companies Dominate Cardiac Defibrillator Market 4Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 2Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 3Complete Data from RegeneRx Phase II Dry Eye Trial Published in Current Issue of Clinical Ophthalmology 4
(Date:5/23/2015)... A live auction will be held to sell over 5,200 ... medical facilities around the United States. Various types of ... exam and much more. , The live auction will ... at 9:00am CDT each day. The equipment is at their ... IL 60160. Anyone can participate in the auction including ...
(Date:5/23/2015)... Viejo, CA (PRWEB) May 23, 2015 Add ... from Pixel Film Studios. , It's as simple as ... as utilizing the included tool for full effect. , ... filmed on high-dynamic range 5k sensors making this the ultimate ... The prismatic flares included in this package are movie files ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 The ... communication and capacity are intersecting to create new ... society, the opening speaker at WesternU's 34th annual ... Lieut. Gov. Gavin Newsom, a former San Francisco ... keynote speaker at the graduation ceremony for WesternU's ...
(Date:5/22/2015)... San Francisco, CA (PRWEB) May 22, 2015 ... is hosting two exciting events in June. They will ... First Professional Doctorate and a two-day class on Classical ... 1:30-2:30 p.m. June 3, Dr. Steve Given, the Dean ... he will discuss the new First Professional Doctorate program. ...
(Date:5/22/2015)... East Liverpool, OH (PRWEB) May 22, 2015 ... today announced that Kyle Johnson, the health system’s Chief ... pursue other interests. Johnson has served as the company ... announced Wesley West will be joining the health system ... operations on an interim basis, while the Board of ...
Breaking Medicine News(10 mins):Health News:Over 5,200 Lots of Medical Equipment Will Be Sold by Live Auction 2Health News:Developers at Pixel Film Studios Release ProFlare 5K Prism for Final Cut Pro X. 2Health News:Newsom to WesternU Grads: The Future is Inside You 2Health News:Newsom to WesternU Grads: The Future is Inside You 3Health News:ACTCM Announces Upcoming June Events 2Health News:River Valley Health Partners Announces CFO Transition, Appointment of Interim CFO 2
... researchers say data show aging alone, not hormonal impact of ... Contradicting the long-held medical belief that the risk of ... from Johns Hopkins suggests instead that heart disease mortality rates ... The findings, published in BMJ , the ...
... Diabetes Risk It is well-documented that lifestyle ... and alcohol consumption affect a person,s risk for diabetes. ... quitting smoking, can delay or prevent the onset of ... affect diabetes risk. Researchers surveyed more than 100,000 men ...
... detected at an early, mild stage, is a significant ... a new, long-term study from Regenstrief Institute and Indiana ... severe stages has an impact on life expectancy similar ... failure. Their findings, "Cognitive Impairment: An Independent Predictor of ...
... , MONDAY, Sept. 5 (HealthDay News) -- Mild ... memory in particular -- may be a stronger predictor ... such as changes in brain volume or levels of ... Spanish researchers looked at 116 people with mild ...
... When it comes to aggressive courtship strategies, sexist men and ... suggests. U.S. researchers conducted two surveys: One included 363 ... was a national Internet poll of 850 adults. The ... toward women and whether they were willing to engage in ...
... , SUNDAY, Sept. 4 (HealthDay News) -- Many teens with ... finds. Researchers analyzed data from a 10-year study of ... were enrolled in special education. The participants were aged 13 ... than 46 percent of the teens with autism used a ...
Cached Medicine News:Health News:Study: No link betweem menopause and increased risk of fatal heart 2Health News:Study: No link betweem menopause and increased risk of fatal heart 3Health News:Embargoed news from Annals of Internal Medicine 2Health News:Embargoed news from Annals of Internal Medicine 3Health News:Even mild cognitive impairment appears to substantially increase risk for death 2Health News:Short-Term Memory Loss May Be Best Predictor of Alzheimer's 2Health News:Sexist Men, Women May Be a Good Fit: Study 2
The Pinn-ACL Femoral Guide is offered in right and left versions and is designed to easily accommodate unusually large or small knees....
Hand surgery basic instrument set...
Needle holder, delicate, curved without lock...
Dilator...
Medicine Products: