Navigation Links
Human Genome Sciences Modifies Dosing in Achieve Trials of Albuferon(R)
Date:1/23/2008

ROCKVILLE, Md., Jan. 23 /PRNewswire-FirstCall/ -- Human Genome Sciences Inc. (Nasdaq: HGSI) announced today that it will modify the dosing in one arm of each of its ACHIEVE clinical trials of Albuferon(R) (albinterferon alfa-2b) for chronic hepatitis C. Patients in the Phase 3 trials who have been receiving the 1200-mcg dose will now receive a 900-mcg dose. The change is based on recommendations made by the studies' independent Data Monitoring Committee (DMC). HGS continues to expect to have all Phase 3 data available by spring 2009 to support the filing of global marketing authorization applications by fall 2009.

(Logo: http://www.newscom.com/cgi-bin/prnh/20010612/HGSLOGO )

"For some time we have viewed the 900-mcg dose administered every two weeks as the most likely marketed dose of Albuferon," said H. Thomas Watkins, President and Chief Executive Officer, HGS. "The 900-mcg dose demonstrated comparable efficacy and safety to Pegasys in Phase 2 - with half the injections, improvements in quality of life and fewer missed days of work during treatment. We continue to believe that Albuferon could become the market-leading interferon for the treatment of hepatitis C if Phase 2 900-mcg results are confirmed in Phase 3."

Consistent with its charter, the DMC routinely reviews all adverse events for each treatment group. Serious pulmonary adverse events, while expected and rare during interferon therapy, were higher in the treatment group receiving 1200-mcg Albuferon administered every two weeks. The DMC did not express any safety concerns about the 900-mcg dose of Albuferon. Based on the DMC's review and conclusions, the patients receiving a 12
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Study Reports Successful Cloning of Human Embryo Using Adult DNA
2. Tengion Launches Third Phase 2 Clinical Trial of Regenerated Human Bladder
3. Novavax Announces Favorable Interim Results from Human Clinical Trial for Its Pandemic Influenza Vaccine Program
4. Medarex Announces Allowance of Investigational New Drug Applications for Wholly Owned Fully Human Anti-CD19 Antibody, MDX-1342
5. U.S. Department of Health and Human Services Completes Funding of 2006 Contract Award to CSCs DVC and Baxter
6. Two Major Studies Show: Human Pluripotent Stem Cells without Cloning or Destroying Embryo
7. Quark Pharmaceuticals, Inc. Announces First Systemic siRNA Dosing in Humans
8. New Data Confirms That a Selective, Fully Human Anti-VEGF Antibody Being Developed by Peregrine is as Effective as Avastin(R) in Preclinical Cancer Models
9. Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus
10. Human Genome Sciences Announces Presentation at AASLD of Results of Phase 2b Trial of Albuferon(R) for Chronic Hepatitis C
11. Human Genome Sciences Presents Results of Phase 2 Trial of Albuferon(R) in Chronic Hepatitis C Patients Who Failed To Respond To Previous Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/1/2014)... -- Dyadic International, Inc. ("Dyadic") (OTCQX: DYAI), a global ... to develop, manufacture and sell enzymes and other proteins ... industries, announced today that it will report its financial ... after market close on Thursday, August 14, 2014 and ... p.m. Eastern Time to discuss those results. ...
(Date:7/31/2014)... , Indien, August 1, 2014 /PRNewswire/ ... und BioQuiddity Inc. gaben heute bekannt, vor ... regionalen Anästhesieanwendungen zur Schmerzbehandlung nach chirurgischen Eingriffen ... das Gebiet der Europäischen Union und weiterer ... CE-Kennzeichnung versehene und mit Ropivacain gefüllte OneDose ...
(Date:7/31/2014)... STAAR Surgical Company (NASDAQ: STAA ... lenses and delivery systems for the eye today reported ... of $20.0 million, a 10% increase over $18.2 million ... constant currency basis, revenues grew 11% during the second ... 2013.  The effect of foreign currency exchange reduced sales ...
Breaking Medicine Technology:Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 2Dyadic International To Announce Second Quarter 2014 Financial Results And Host Conference Call On Thursday, August 14, 2014 3Cipla und BioQuiddity geben EU-Geschäftspartnerschaft für OneDose-ReadyfusOR zur Schmerzbehandlung nach chirurgischen Eingriffen bekannt 2Cipla und BioQuiddity geben EU-Geschäftspartnerschaft für OneDose-ReadyfusOR zur Schmerzbehandlung nach chirurgischen Eingriffen bekannt 3STAAR Surgical Reports 10% Second Quarter Revenue Growth 2STAAR Surgical Reports 10% Second Quarter Revenue Growth 3STAAR Surgical Reports 10% Second Quarter Revenue Growth 4STAAR Surgical Reports 10% Second Quarter Revenue Growth 5STAAR Surgical Reports 10% Second Quarter Revenue Growth 6STAAR Surgical Reports 10% Second Quarter Revenue Growth 7STAAR Surgical Reports 10% Second Quarter Revenue Growth 8STAAR Surgical Reports 10% Second Quarter Revenue Growth 9STAAR Surgical Reports 10% Second Quarter Revenue Growth 10STAAR Surgical Reports 10% Second Quarter Revenue Growth 11STAAR Surgical Reports 10% Second Quarter Revenue Growth 12STAAR Surgical Reports 10% Second Quarter Revenue Growth 13STAAR Surgical Reports 10% Second Quarter Revenue Growth 14STAAR Surgical Reports 10% Second Quarter Revenue Growth 15STAAR Surgical Reports 10% Second Quarter Revenue Growth 16STAAR Surgical Reports 10% Second Quarter Revenue Growth 17STAAR Surgical Reports 10% Second Quarter Revenue Growth 18STAAR Surgical Reports 10% Second Quarter Revenue Growth 19STAAR Surgical Reports 10% Second Quarter Revenue Growth 20STAAR Surgical Reports 10% Second Quarter Revenue Growth 21STAAR Surgical Reports 10% Second Quarter Revenue Growth 22STAAR Surgical Reports 10% Second Quarter Revenue Growth 23STAAR Surgical Reports 10% Second Quarter Revenue Growth 24STAAR Surgical Reports 10% Second Quarter Revenue Growth 25STAAR Surgical Reports 10% Second Quarter Revenue Growth 26STAAR Surgical Reports 10% Second Quarter Revenue Growth 27STAAR Surgical Reports 10% Second Quarter Revenue Growth 28STAAR Surgical Reports 10% Second Quarter Revenue Growth 29STAAR Surgical Reports 10% Second Quarter Revenue Growth 30STAAR Surgical Reports 10% Second Quarter Revenue Growth 31
... , BOSTON, Nov. 17 ... and information management solutions, today announced that it will showcase ... (IDNs) at the 2009 Radiological Society of North America (RSNA) ... IL. AMICAS will be in the North Hall in booth ...
... HistoRx today announced that the Company,s proprietary AQUA technology, ... was noted in a recent National Comprehensive Cancer ... testing in breast cancer as one of the "... promising ... PgR in breast cancer tissue." Experts from the country,s ...
Cached Medicine Technology:AMICAS' Enterprise Image Management Solutions To Be Showcased at RSNA 2009 2AMICAS' Enterprise Image Management Solutions To Be Showcased at RSNA 2009 3AQUA(R) Technology Recognized as 'Promising New Strategy' for Hormone Receptor Testing in Breast Cancer by NCCN Task Force 2
(Date:8/1/2014)... 01, 2014 Cannabis use among young people ... 14 to 17 having used marijuana at least once and ... slogan “Say ‘No’ to Drugs, Say ‘Yes to Life,’ volunteers ... to youth this summer with factual information about drugs, to ... months, Hamburg “Say ‘No’ to Drugs, Say ‘Yes’ to Life,” ...
(Date:8/1/2014)... Washington University School of Medicine in St. Louis helps ... and frequently are more harmful than similar tumors in ... tumors, are diagnosed twice as often in males, who ... survive as long. , The researchers found that retinoblastoma ... is significantly less active in male brain cells than ...
(Date:8/1/2014)... HealthDay Reporter FRIDAY, Aug. 1, ... manufacturing jobs may have significantly less endurance than those who weigh ... people -- half were obese, half were of normal weight -- ... 60 percent longer. Obesity also was associated with less strength, ... older -- 50 to 65 years of age -- neither improved ...
(Date:8/1/2014)... News) -- Almost 140 people die every year ... United States. But there are several simple ... injury prevention coordinator at Cincinnati Children,s Hospital Medical ... medical center news release. "As families begin ... important for parents and children to go over ...
(Date:8/1/2014)... 2014 Summer is here, and with it ... the summer, and they can be a pain for dogs. ... help all their customers get rid of ticks and prevent ... eggs in the summer, which is why they are so ... grass and woodland areas and carry a number of diseases, ...
Breaking Medicine News(10 mins):Health News:Addressing a Serious Issue Affecting German Teens 2Health News:Study reveals one reason brain tumors are more common in men 2Health News:Obesity Might Slow You Down at Work 2Health News:Obesity Might Slow You Down at Work 3Health News:Expert Offers School Bus Safety Tips 2Health News:Tis the Season for Tick Prevention 2
... each year , , THURSDAY, Jan. 15 (HealthDay News) -- A ... is 300 times more likely to die during pregnancy or ... annual report released Thursday shows. , The State of ... in developing nations have a 14-fold higher chance of dying ...
... Online Care service available to all Hawaii residents.HONOLULU, Jan. 15 ... launch of its new Online Care service that connects patients ... Care is now available to everyone in Hawaii and may ... not have to be an HMSA member to use the ...
... a leading middle market investment bank recently released ... Information and Technology M&A Trends Report . ... 2008 and compares it with activity during the ... and healthcare information and technology markets.(Photo: ...
... Nonin Medical, Inc., a leading,innovator of physiological ... SIG Best of CES 2009 award for the ... world,s first wireless fingertip oximeter,the innovative device combines ... -- enabling individuals to accurately,monitor vital signs. , ...
... sell homes, seniors increasingly turning to home care vs. ... real estate crisis has affected all aspects of life, ... seniors unable to sell their homes, moving to an ... this reason, the option of aging-in-place with retrofits is ...
... because they may lead to blood clots, study says ... birth control pills don,t seem to increase the risk of ... study says. , But more research on the newer ... This is especially true because more women over age 35 ...
Cached Medicine News:Health News:Mothers, Newborns at High Risk in Developing World 2Health News:First in the Nation, HMSA's Online Care Goes Live 2Health News:First in the Nation, HMSA's Online Care Goes Live 3Health News:First in the Nation, HMSA's Online Care Goes Live 4Health News:Berkery Noyes Report Shows Pharma and Healthcare Information and Technology M&A Remained Strong in 2008 2Health News:Nonin Medical's Onyx(R) II, Model 9560 Receives Bluetooth SIG's Best of CES 2009 Award 2Health News:Housing Crisis Affects Seniors Needing Care 2Health News:Housing Crisis Affects Seniors Needing Care 3Health News:Newer Contraceptives Don't Increase Heart Risk 2Health News:Newer Contraceptives Don't Increase Heart Risk 3
... Proven tension-free sling technology ... porcine acellular collagen matrix sling, ... tissue-to-tissue contact between sling and ... urethral or vaginal abrasion or ...
... Delivers the advanced performance ... exceptional strength, versatility, and durability ... implant that augments the effectiveness ... pelvic floor reconstruction. Comprised of ...
... system is a state-of-the-art, comprehensive cardiac ... programs, modalities, and parameters are highly ... multiple applications including cardiac and pulmonary ... clinics. Its open architecture delivers flexibility ...
NephroMax High Pressure Nephrostomy Balloon Catheter allows one-step, atraumatic dilatation of the nephrostomy tract....
Medicine Products: