Navigation Links
Human Genome Sciences Completes Enrollment in Second Phase 3 LymphoStat-B(R) Trial
Date:8/27/2008

indicate a severe flare of lupus disease activity) and no more than one new BILAG B organ domain score (which would indicate a moderate flare of disease activity).

In each of the two Phase 3 trials, patients have been randomized to one of three treatment groups: 1 mg/kg belimumab, 10 mg/kg belimumab, or placebo. Patients are dosed intravenously on Days 0, 14 and 28, then every 28 days for the duration of the study. All receive standard of care therapy in addition to the study medication. Safety and tolerability are evaluated by an independent Data Monitoring Committee throughout both studies.

About LymphoStat-B (belimumab)

Belimumab is a human monoclonal antibody that specifically recognizes and inhibits the biological activity of B-lymphocyte stimulator, or BLyS(R). BLyS is a naturally occurring protein discovered by HGS that is required for the development of B-lymphocyte cells into mature plasma B cells. Plasma B cells produce antibodies, the body's first line of defense against infection. In lupus and certain other autoimmune diseases, elevated levels of BLyS are believed to contribute to the production of autoantibodies - antibodies that attack and destroy the body's own healthy tissues. The presence of autoantibodies appears to correlate with disease severity. Preclinical and clinical studies demonstrate that B-cell antagonists can reduce autoantibody levels and help control autoimmune disease activity.

About Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic, life-threatening autoimmune disease. Approximately 1.5 million people in the United States and approximately 5 million worldwide suffer from various forms of lupus, including SLE. Lupus can occur at any age, but appears mostly in young people ages 15 to 45. About 90 percent of those diagnosed with lupus are women. African-American women are about three times more likely to develop lupus, and it is also more common in Hispanic, Asian and America
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Video: New Research Discovers Independent Brain Networks Control Human Walking
2. Lpath Demonstrates Strong Safety Profile of Lead Drug Candidate, Sphingomab(TM), in Non-Human Primates
3. Enrollment Begins on Human PK Study for Medidur(TM) FA
4. Human Genome Sciences Completes Enrollment of First Phase 3 Albuferon(R) Trial Ahead of Schedule
5. Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006
6. Lpath Demonstrates Preclinical Efficacy of Lpathomab(TM) and Initiates Humanization Process
7. Peregrine Researchers Report Data Showing Bavituximabs Potential to Shrink Human Prostate Tumors in Model of Relapsed Disease
8. Dr. Roger Kenneth Hershline PhD MD, CEO of Global Humanceuticals, Inc. Donates New HIV Drug
9. Study Shows Plasma-Derived Human Thrombin Equivalent to Bovine Thrombin in Achieving Hemostasis in Surgery
10. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
11. Flexible Medical Systems Raises $1.2M Seed Investment for Initial Human Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... , Oct. 18, 2014  In a ... Campaign (HRC), the nation,s largest lesbian, gay, bisexual ... the use of Truvada for Pre-Exposure Prophylaxis (PrEP). ... used to prevent the spread of a disease ... only brand name anti-HIV drug combination currently approved ...
(Date:10/17/2014)... , Oct. 17, 2014 UBM Medica US ... a leading online community and information resource for neurologists and ... and Alzheimer disease , with discussions of the ... 1 million Americans have Parkinson disease , more than ... or Lou Gehrig disease. Diagnosis can be difficult ...
(Date:10/17/2014)... 2014 A victim of medical negligence at the ... with a history of alcohol abuse, a physician and consumer ... 46 today, highlighting how Prop 46 will identify and deter ... The ad pictures a doctor drinking at a ...  Proposition 46 will enact the first law in the nation ...
Breaking Medicine Technology:HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 2HRC Endorses PrEP, Calls for Bold Action to Expand Access to Anti-HIV Drug 3Neurology Times Features Coverage of Parkinson and Alzheimer Disease 2Neurology Times Features Coverage of Parkinson and Alzheimer Disease 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 2Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 4
... Measuring the body temperatures of newborns with ... rectal thermometers, according to a cross-sectional study recently ... thermometry methods are necessary when measuring neonate temperatures. ... at the Sanglah Hospital within the Neonatology Division ...
... 15, 2011 Dynatronics Corporation (Nasdaq: DYNT ) ... $1 million open market share repurchase program of the company,s ... of management and our board of directors in the future ... said Kelvyn H. Cullimore, president of Dynatronics. "Based on recent ...
Cached Medicine Technology:New Study Finds Temporal Artery Thermometry Equivalent to Rectal Thermometry 2Dynatronics Announces $1 Million Stock Buyback Program 2
(Date:10/20/2014)... October 20, 2014 Zereana Jess-Huff, a 34-year-old ... Maryland 2014 on a platform to think outside the bra. ... uses her position to raise awareness about women’s other lady ... breast cancer. You say the color pink and everybody knows ... for a fact that it has not been won when ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 ... Voicheck as Assistant Director of their CentralSource ... in managing the innovative turnkey drug sourcing, distribution, ... Matthew brings over 12 years of industry experience, ... Myoderm at the peak of their international success ...
(Date:10/20/2014)... Final Cut Pro X Plugin developers from ... theme for FCPX filmmakers . , “Fun, cool, and ... Citrus theme” Says Christina Austin, CEO of Pixel Film Studios. ... , Citrus comes with all the tools needed for a ... transitions for added style, a title screen for an introduction, ...
(Date:10/20/2014)... October 20, 2014 Do you ever ... Here comes a wonderful app Metassessor for teachers, specialists ... company helped its client “Intervention Development LLC” to ... app is designed for iOS 4.3 or later and ... app is optimized for iPhone 5. It is now ...
(Date:10/19/2014)... Dallas, Texas (PRWEB) October 20, 2014 ... therapeutic development for Partial Seizure, complete with comparative ... target, mechanism of action (MoA), route of administration ... and featured news and press releases. It also ... for Partial Seizure and special features on late-stage ...
Breaking Medicine News(10 mins):Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 2Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 3Health News:Myoderm Hires Matthew Voicheck to Lead Turnkey Drug Sourcing Service 2Health News:Today Pixel Film Studios Announced the Release of the Citrus theme for Final Cut Pro X 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 2Health News:Metassessor App Launched: an RTI tool for Teachers & Parents 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 4
... Ramadoss has added a new twist to the cola row ... added pesticides.// , ,"All carbonated drinks like Pepsi and ... a comprehensive policy on such drinks are needed," he said ... of Madras Medical College. ,Ramadoss added that the issue ...
... and Prevention say that mothers who are at a low-risk ... deliver their baby by C-section// rather than vaginally. The report ... Perinatal Care. For the study researchers looked at 5.7 million ... ,In general, neonatal ( ,The overall rate ...
... Boston have discovered a new common, noncoding variant in ... with age-related macular degeneration// (AMD), the leading cause ... 60 and older. Their analyses, for the first time, ... to estimate individual risk of advanced AMD. They observed ...
... people and the possible link between these changes and the ... Forest University School of Medicine// . ,Comparison of ... disorder with the tissue from normal people will be done ... from the National Institute of Mental Health. ,The ...
... Institutet in Sweden and Makerere University in Uganda finds that ... and this is the reason for pregnant women and children ... worst of the four malaria parasites that infect man. It ... of pregnant women, with fatal consequences for both her and ...
... claim to have discovered how a specific chemotherapy drug helps ... was conducted on the use of a virus in animals ... led by scientists from the Ohio State University Comprehensive Cancer ... Research Institute, and has been published in the August 22nd ...
Cached Medicine News:Health News:Cesarean Section May Increase Infant Mortality Rates in Low-Risk Women 2Health News:AMD influenced by Variation in 3 Genes 2Health News:AMD influenced by Variation in 3 Genes 3Health News:Brain changes in schizophrenia to be analyzed 2Health News:Brain changes in schizophrenia to be analyzed 3Health News:Malarial Parasite Hides In Placenta 2Health News:Cancer Drug Helps An Anti-Cancer Virus To Act More Exhaustively 2Health News:Cancer Drug Helps An Anti-Cancer Virus To Act More Exhaustively 3
Designated most popular model or size. Double-ended. 2 mm wide....
Heavy. 7.5 mm curved tip....
Desmarres Infant Retractor...
2.0 mm cup , straight shaft, Flat handle, length 125.0 mm....
Medicine Products: