Navigation Links
Human Genome Sciences Completes Enrollment in Randomized Phase 2 Trial of HGS-ETR1 in Non-Small Cell Lung Cancer
Date:8/22/2008

ROCKVILLE, Md., Aug. 22 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI) today announced that it has completed the enrollment and initial dosing of patients in a randomized Phase 2 trial of HGS-ETR1 (mapatumumab) in combination with the chemotherapy agents paclitaxel and carboplatin as first-line therapy in advanced non-small cell lung cancer (NSCLC).

(Logo: http://www.newscom.com/cgi-bin/prnh/20080416/HGSLOGO )

"There is an urgent medical need for effective treatment options for non- small cell lung cancer because current treatment strategies have only a minimal impact on survival," said Joachim von Pawel, M.D., a principal investigator in the study from the Asklepios Fachkliniken Munchen-Gauting, Germany. "The majority of patients who are newly diagnosed with non-small cell lung cancer have locally advanced or metastatic disease that is currently incurable. We look forward to evaluating the potential of mapatumumab plus chemotherapy to offer a new approach to the first-line treatment of this deadly disease."

The NSCLC trial is a randomized, multi-center, open-label Phase 2 study to evaluate the efficacy and safety of HGS-ETR1 in combination with carboplatin and paclitaxel as first-line therapy in the treatment of advanced non-small cell lung cancer (Stage IIIB or IV). 111 patients have been randomly assigned to one of three treatment groups and treated with either the two-agent combination of carboplatin and paclitaxel or the three-agent combination of carboplatin, paclitaxel, and HGS-ETR1 at either 10 mg/kg or 30 mg/kg. HGS announced the initiation of the NSCLC trial In December 2007.

"A growing body of precl
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Boston University and The Center for Human Genetics, Inc. Announce Change in Testing Services
2. ViaViente Demonstrates Cardiovascular Benefits in New Human Trial
3. Lixte Biotechnology Holdings Announces That Novel Compounds Being Developed as Potential Treatments for Brain Tumors Have Positive Activity in a Mouse Model of Human Pancreatic Cancer
4. ProteoTechs Exebryl-1(R) Enters Human Clinical Trials for the Treatment of Alzheimers Disease
5. Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-PD-L1 Antibody, MDX-1105
6. deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia
7. New Research on Pre-Eclampsia in Mice May Have Important Implications for Humans
8. Ekkyo Describes the First Benefits of Controlled Hyperthermia in Humans in "Lasers in Surgery and Medicine"
9. Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data
10. Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company
11. IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following June Meeting of European Committee for Medicinal Products for Human Use (CHMP)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... Calif. , May 24, 2013 Solta Medical, ... the medical aesthetics market, today reported Dr. Edward ... the Company,s Board of Directors effective immediately.  Dr. Knowlton is ... and had served as a director since 1996. ... as our management team, I would like to thank Ed ...
(Date:5/24/2013)... China Biologic Products, Inc. (Nasdaq: CBPO, "China Biologic" or ... in China , today announced that ... issued by Shanghai RAAS Blood Products Co., Ltd. ("Shanghai ... that on May 21, 2013, Ms. Siu ... shareholders of the Company, and her spouse, Mr. Tung ...
(Date:5/24/2013)... , May 24, 2013  Sinovac Biotech ... provider of biopharmaceutical products in China ... operating subsidiary company of Sinovac, obtained the Certificate ... Certificate) from the China State and Food Administration ... bulk production plants, and its Changping filing and ...
Breaking Medicine Technology:Dr. Edward W. Knowlton Resigns as a Director of Solta Medical, Inc. 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 2China Biologic Comments on the Proposed Shanghai RAAS Transaction 3China Biologic Comments on the Proposed Shanghai RAAS Transaction 4Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 3
... ALTO, Calif., Oct. 12 Varian, Inc. (Nasdaq: ... for its 710-ES Series of ICP-OES (Inductively Coupled Plasma ... hardware, software and accessory options available both on new ... They enable users to reduce sample analysis times by ...
... Ill., Oct. 12 Hospira, Inc. (NYSE: HSP ), ... announced that the company will present at the Credit Suisse ... Phoenix, Ariz. , The presentation is scheduled to begin at ... It will be available to all interested parties through ...
Cached Medicine Technology:Varian, Inc. Delivers a Productivity Increase of Up to 100% With Its 710-ES Series ICP-OES 2Varian, Inc. Delivers a Productivity Increase of Up to 100% With Its 710-ES Series ICP-OES 3
(Date:5/25/2013)... 2013 Pradaxa lawsuits filed ... of internal bleeding while using the blood thinner continue to ... Southern District of Illinois, Bernstein Liebhard LLP reports. According ... effect claims had been filed in the litigation ... claims reported by the Court on May 15th. ( In ...
(Date:5/25/2013)... According to a new market report,"Global Homeland Security ... is expected to reach $544.02 Billion by 2018 ... studies the major market drivers, restraints, and opportunities ... the World. , Browse:, , ... Figures , 175 Pages and in-depth ...
(Date:5/25/2013)... Acuity Games ’ innovative brain games ... Word Hunt is available today, expanding it beyond ... Flash 2, Sudoku and Matchematics will roll out over the ... revolutionary lifetime brain fitness measurement have been re-optimized for the ... of brain fitness measurement in your pocket. What could ...
(Date:5/25/2013)... May 25, 2013 For college ... finals week. Increasingly, they are turning to prescription ... and study. For more on this, go to ... treatment facility, warns that students who pick up ... at risk for developing a physical and psychological ...
(Date:5/25/2013)... Flagstaff, Arizona (PRWEB) May 25, 2013 The ... Rehabilitation Center, their parents, and the B2B staff all came ... While everyone enjoyed an array of Indian Cuisine, the residents ... the company, for helping them on their road to recovery, ... started the Drug and Alcohol center in 2010 after realizing ...
Breaking Medicine News(10 mins):Health News:Pradaxa Lawsuits Mount, as Filings in Federal Pradaxa Side Effect Litigation Exceed 800, Bernstein Liebhard LLP Reports 2Health News:Pradaxa Lawsuits Mount, as Filings in Federal Pradaxa Side Effect Litigation Exceed 800, Bernstein Liebhard LLP Reports 3Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 2Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 3Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 4Health News:Acuity Games Apps Come to the iPhone 2Health News:Addiction and Drug Abuse: Study Drug Adderall Abuse Spikes During Finals 2Health News:Back2Basics Drug and Alcohol Rehabilitation Center Celebrates Their 3rd Anniversary 2
... Poor communication of the outcomes of medical tests whose ... hospital discharge is common and can lead to serious ... new study by researchers from the Regenstrief Institute and ... hospital discharge summaries are grossly inadequate at documenting both ...
... - Hard to Treat Diseases, Inc. (HTDS:PK), ( http://www.htdsmedical.com ... (Mellow Hope) announced today that the general manager of ... to a significant new business development opportunity related to ... to participate in a formal tender process to supply ...
... , , JEDDAH, Saudi ... feel beautiful and good about themselves, and Saudi women are ... which is such a strong guiding force in the kingdom? ... strict Muslim country. , http://susiesbigadventure.blogspot.com/2009/08/plastic-surgery-in-saudi-arabia.html ...
... that could change if fall outbreak proves more severe, ... The school closures that swept across the United States ... flu needn,t be repeated this fall, according to new ... the same guidelines noted that everything could change if ...
... Pharmaceutical Institute, a leading provider of specialized training solutions ... O,Grady has been appointed Senior Vice President and General Manager ... will manage the day-to-day operations of the business, as well ... teams. , , Mr. O,Grady has over ...
... , NEW YORK, Aug. 7 A ... vaccines beyond those received when they were infants or small children. ... most pre-teens and teens do not have all the vaccinations that ... certain diseases and protection from some childhood vaccines can wear off ...
Cached Medicine News:Health News:Fumbled handoffs can lead to medical errors 2Health News:Hard To Treat Diseases (HTDS) Chile Flu Vaccine Tender 2Health News:Hard To Treat Diseases (HTDS) Chile Flu Vaccine Tender 3Health News:Hard To Treat Diseases (HTDS) Chile Flu Vaccine Tender 4Health News:School Closures May Not Be Necessary When Swine Flu Strikes 2Health News:School Closures May Not Be Necessary When Swine Flu Strikes 3Health News:School Closures May Not Be Necessary When Swine Flu Strikes 4Health News:Garry O'Grady Appointed Senior Vice President and General Manager of Pharmaceutical Institute 2Health News:Photo: New Survey Results Show Most Moms Are Aware Their Pre-teens and Teens Need Vaccines 2Health News:Photo: New Survey Results Show Most Moms Are Aware Their Pre-teens and Teens Need Vaccines 3
Sub Pectoral Bra...
Bandeau Bra...
Post-Surgical compression garments...
... Cobalt Binding (ACB®) Test is a clinical ... (IMA®) by measuring the cobalt binding capacity ... First identified in the early 1990s, IMA ... contact with ischemic tissue in the heart. ...
Medicine Products: