Navigation Links
Human Genome Sciences Completes Enrollment in Randomized Phase 2 Trial of HGS-ETR1 in Non-Small Cell Lung Cancer
Date:8/22/2008

ROCKVILLE, Md., Aug. 22 /PRNewswire-FirstCall/ -- Human Genome Sciences, Inc. (Nasdaq: HGSI) today announced that it has completed the enrollment and initial dosing of patients in a randomized Phase 2 trial of HGS-ETR1 (mapatumumab) in combination with the chemotherapy agents paclitaxel and carboplatin as first-line therapy in advanced non-small cell lung cancer (NSCLC).

(Logo: http://www.newscom.com/cgi-bin/prnh/20080416/HGSLOGO )

"There is an urgent medical need for effective treatment options for non- small cell lung cancer because current treatment strategies have only a minimal impact on survival," said Joachim von Pawel, M.D., a principal investigator in the study from the Asklepios Fachkliniken Munchen-Gauting, Germany. "The majority of patients who are newly diagnosed with non-small cell lung cancer have locally advanced or metastatic disease that is currently incurable. We look forward to evaluating the potential of mapatumumab plus chemotherapy to offer a new approach to the first-line treatment of this deadly disease."

The NSCLC trial is a randomized, multi-center, open-label Phase 2 study to evaluate the efficacy and safety of HGS-ETR1 in combination with carboplatin and paclitaxel as first-line therapy in the treatment of advanced non-small cell lung cancer (Stage IIIB or IV). 111 patients have been randomly assigned to one of three treatment groups and treated with either the two-agent combination of carboplatin and paclitaxel or the three-agent combination of carboplatin, paclitaxel, and HGS-ETR1 at either 10 mg/kg or 30 mg/kg. HGS announced the initiation of the NSCLC trial In December 2007.

"A growing body of precl
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Boston University and The Center for Human Genetics, Inc. Announce Change in Testing Services
2. ViaViente Demonstrates Cardiovascular Benefits in New Human Trial
3. Lixte Biotechnology Holdings Announces That Novel Compounds Being Developed as Potential Treatments for Brain Tumors Have Positive Activity in a Mouse Model of Human Pancreatic Cancer
4. ProteoTechs Exebryl-1(R) Enters Human Clinical Trials for the Treatment of Alzheimers Disease
5. Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-PD-L1 Antibody, MDX-1105
6. deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia
7. New Research on Pre-Eclampsia in Mice May Have Important Implications for Humans
8. Ekkyo Describes the First Benefits of Controlled Hyperthermia in Humans in "Lasers in Surgery and Medicine"
9. Vical Announces Breakthrough for Pandemic Influenza DNA Vaccines With Preliminary Human Data
10. Insmed Announces First Human Bioequivalence Data for a Follow-on Biologic by a U.S. Company
11. IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following June Meeting of European Committee for Medicinal Products for Human Use (CHMP)

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/25/2009)...OVELAND, Colo., Nov. 25 ...ovider of advanced diagnostic and specialty prod...greements with Roche Diagnostics Corporation for t...sumables for the veterinary market. ,, (Logo...ESKALOGO ) ,, "Heska and Roche share the same p...
(Date:11/25/2009)...ON, Pa., Nov. 25 BioTrends Researc...s(TM) : Stelara report, the first in a multi-...the launch of Centocor Ortho-Biotech,s Stelara, fr...availability. Each wave of the report provides qu...ts and qualitative information from a subset of 20...
(Date:11/25/2009)...KING RIDGE, N.J., Nov. 25 Regado B...evelopment of antithrombotic aptamers with active ...EO and President, will be presenting at the Piper ...New York Palace Hotel in New York City. Dr. Mazzo...uesday, December 1 and will include an overview of...
Breaking Medicine Technology:Heska Announces Supply Agreement With Roche Diagnostics 2Heska Announces Supply Agreement With Roche Diagnostics 3Despite Managed Care Obstacles, Interest and Anticipated Use of Centocor Ortho-Biotech's New Psoriasis Agent Stelara (ustekinumab) is High 2Regado Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference on December 1, 2009 2Two New Easy To Use Training Computers from Polar Simplify the Benefits of Exercising with Heart Rate 60154 1Two New Easy To Use Training Computers from Polar Simplify the Benefits of Exercising with Heart Rate 60154 2Two New Easy To Use Training Computers from Polar Simplify the Benefits of Exercising with Heart Rate 60154 3New Poll Shows Americans Want Medical Liability Reform 60150 1New Poll Shows Americans Want Medical Liability Reform 60150 2TOPAZ Technologies Announces SoBran Inc as New Customer 14612 1TOPAZ Technologies Announces SoBran Inc as New Customer 14612 2TOPAZ Technologies Announces SoBran Inc as New Customer 14612 3
(Date:11/28/2009)...erts offer tips to help lift spirits, recognize si...(HealthDay News) -- For many seniors, the holiday ...lost loved ones, struggle with health issues or wo...n Geriatrics Society. , To help overcome the se...ng offers the following advice: , Get out and so...
(Date:11/27/2009)... , DALLAS, Nov. 27 /PRNewswire-USNewswire/ -...cal procedure only 25 years ago, solid organ trans...on thanks to the extraordinary men and women who g...ov. 11. Leaders came together from medical centers...y of Baylor Regional Transplant Institute (BRTI), ...
(Date:11/27/2009)... , KIBBUTZ SHAMIR, Israel, Nov. 27 /PRNewswir...aq: SHMR ) ( "Shamir" ), a leading provider of in... lens market, announced today that its board of di... aggregate amount of US$ 10 million (approximately...representative rate of exchange), or approximately...
(Date:11/27/2009)... , SEATTLE, Nov. 27 /PRNewsw...te, received record-high Thanksgiving traffic numb...efore Thanksgiving, providing a clear picture of w...year. The average Thanksgiving meal in 2009 weighe...crease from last year,s feast. According to the Al...
(Date:11/27/2009)... Three new interactive anato...liams & Wilkins expand health sciences learnin... Durham, NC (Vocus) November 27,...& Wilkins (LWW), a division of Wolters Kluwer ...new anatomy education apps on the App Store. Cleme...
Breaking Medicine News(10 mins):Health News:Seniors May Need Help Overcoming Holiday Blues 2Health News:Organ Transplant Pioneers Celebrate Baylor Regional Transplant Institute's 25th Anniversary 2Health News:Organ Transplant Pioneers Celebrate Baylor Regional Transplant Institute's 25th Anniversary 3Health News:Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 2Health News:Shamir Optical Industry Ltd. Announces Declaration of a Cash Dividend 3Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 2Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 3Health News:It's Black Friday - Time to Shop Off the Calories! Allrecipes Finds Average Thanksgiving Meal Weighed in at 2,225 Calories 4Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 2Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 3Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 4Health News:Clemente's Anatomy, Rohen's Photographic Anatomy, and Moore's Clinical Anatomy Customizable Apps Now Available on App Store 5
...or its complementary therapy. Silymarin, is a mixt...believed to contain a number of active constituent...inst poisoning. Hence,its wide use in the t...also help control blood sugar levels in patients s...
...ugh an artificial pancreas which is supposed to mo... provides insulin automatically. This could free c... tests and injections. Around 350,000 Britons...e method for sufferers to monitor their blood suga...
...cur in kids who had low levels of iron as infants....// The study conducted on 185 Costa Rican te...d Adolescent Medicine. It reveals the need for ear...ect and indirect effects of early iron deficiency ...
... Indiana have no one to look out for them. They ar...s //or in the community without any money or famil...ental retardation or another condition that impair...te-funded program that is assigned to help at leas...
...rd flu virus H5N1 will at some point in the future...ty //being "when?" This would be a truly horrifyin... a science fiction film. The WHO figures are...reak could take place within a few weeks . This is...
...tice of using duct tape a strong wide adhesive tap... crop up on skin of hands or feet in schoolchildre...ata which disproves the popularly attested belief ...r than a regular corn pad which itself is consider...
Other Medicine News:Health News:A Wonder Drug From Milk Thistle 2Health News:Lives of Diabetics Transformed 2Health News:Low Iron levels in infants lead to brain defects 2Health News:Hoosiers Live at the Mercy of Nursing Homes 2Health News:Hoosiers Live at the Mercy of Nursing Homes 3Health News:Human Strain Of Bird Flu Virus, Just A Matter Of Time? 2
...eDoc is a user friendly computerized medical recor...and productivity of the practice as well as improv...s clinical templates for commonly presenting probl... an exhaustive database to cover rare diagnostic e...
Veatch Z-1
ReSeeVit 5V
...ring your percent free PSA will help improve the a... in multiple forms in the blood. Most is bound to ...1990s, it was discovered that measuring the ratio ...tinguishing prostate cancer from benign prostate d...
Medicine Products: