Navigation Links
Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
Date:4/22/2008

jects.

"The results of previous studies suggest that belimumab significantly reduced SLE disease activity in serologically active patients," said Professor Sandra V. Navarra, M.D., a principal investigator and head of Rheumatology at the University of Santo Tomas, Manila, Philippines. "There is a great need for better tolerated and more effective treatments for lupus, and we look forward to seeing the first Phase 3 data for belimumab by mid-2009."

About the LymphoStat-B Phase 3 Development Program

The LymphoStat-B Phase 3 development program includes two double-blind, placebo-controlled, multi-center Phase 3 superiority trials -- BLISS-52 and BLISS-76 -- to evaluate the efficacy and safety of LymphoStat-B plus standard of care, versus placebo plus standard of care, in patients with serologically active SLE. The design of the two trials is similar, but the duration of therapy in the two studies is different -- 52 weeks for BLISS-52 and 76 weeks for BLISS-76. The data from BLISS-76 will be analyzed after 52 weeks in support of a potential Biologics License Application (BLA). HGS designed the LymphoStat-B Phase 3 program in collaboration with GSK and leading international SLE experts.

"A total of nearly 1700 patients worldwide will be enrolled and randomized in the Phase 3 trials of belimumab, making this the largest double-blinded clinical development program ever undertaken in lupus patients," said William W. Freimuth, M.D., Ph.D., Vice President, Clinical Research - Immunology, Rheumatology and Infectious Diseases, HGS. "Today's milestone brings us closer to seeing Phase 3 data that we hope will confirm belimumab's promise as a potential treatment for patients with SLE. We are grateful for the superb performance of our clinical investigators, whose diligence made it possible to complete the enrollment of BLISS-52 ahead of our fall 2008 projection."

The primary efficacy endpoint of BLISS-52 and BLISS-76 is the patient response rate
'/>"/>

SOURCE Human Genome Sciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Tepha Announces First Human Usage of Medical Devices Derived from New Class of Resorbable Polymers
2. Data Show SuperGens MP-470 is Safe in Humans
3. Longevinex(R) Found to be Superior to Green Tea Molecule in Independent Human Study
4. CardioMind Launches First-in-Human Trial of Small Vessel, Drug-Eluting Stent
5. Gen-Probe Begins U.S. Clinical Study of Molecular Test for Human Papillomavirus, Which Causes Cervical Cancer
6. ExonHits EHT 0202 Counters Scopolamines Detrimental Effects on Cognition in Humans
7. Valor Medical Announces First Human Implant of Neucrylate AN(TM) for Treatment of Cerebral Aneurysm
8. Synbiotics Corporation Announces Human Submission for FluDetect(R)
9. GeoVax Vaccine Only 5th AIDS Vaccine Moving to Phase 2 Human Trials
10. Ardea Biosciences Presents Preclinical Data Demonstrating Favorable Resistance Profiles for Non-Nucleoside Reverse Transcriptase Inhibitors for the Treatment of Human Immunodeficiency Virus
11. N30 Pharma Announces Successful Initiation of Human Studies With N30-201
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... Mass. , Sept. 15, 2014 /PRNewswire/ ... Digital MedTech Physician™ 2014, finds that online ... ways for brands to differentiate their offering ... for medical device purchasing decisions rely on ... for learning about devices—and these physicians are ...
(Date:9/15/2014)... 15, 2014 The Society of Corporate ... serving more than 4,500 compliance and ethics professionals ... which chronicles corporate fines and settlements.  The SCALENDAR ... have a ready reference to demonstrate to employees ... the SCALENDAR to help compliance and ethics officers ...
(Date:9/15/2014)... -- Research and Markets has announced the addition ... Tests, 9th Edition" report to their offering. ... testing market and all of its segments, providing customers with ... For Business Planning. This is the ninth edition ... 2013 and early 2014. New entrants, new technologies have entered ...
Breaking Medicine Technology:Physician device decision-makers show strong demand for device manufacturer digital content and support 2Physician device decision-makers show strong demand for device manufacturer digital content and support 3More than $55 billion in fines and settlements added by SCCE to its 2015 Corporate Scandal Calendar 2The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 2The Worldwide Market for In Vitro Diagnostic Tests, 9th Edition 3
... N.J., Dec. 17 BASF today announced that ... Aseptrol® S10 - Tab in H1N1 sanitization operations in institutional ... and restaurants, and recreational facilities. Aseptrol S10 - Tab ... S10 - Tab delivers a broad spectrum disinfectant as ...
... , NASHVILLE, Tenn. , Dec. 16 ... management services, today commended two new studies highlighting the dangers ... imaging tests. , "When used properly, CT imaging is ... chief medical officer of MedSolutions. "However, these new studies offer ...
Cached Medicine Technology:BASF's Aseptrol(R) S10 - Tab Receives EPA Approval For H1N1 Sanitization Label 2BASF's Aseptrol(R) S10 - Tab Receives EPA Approval For H1N1 Sanitization Label 3MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 2MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 3
(Date:9/16/2014)... 16, 2014 Triad Semiconductor, Inc. today ... of Intersil and former President of Linear Technology Corporation ... “David has extraordinary technology and business expertise, and we ... directors,” said Lynn Hayden, Triad CEO and chairman. , ... and mixed signal semiconductor experience to Triad's board. From ...
(Date:9/15/2014)... 16, 2014 The team of defective ... Danis & Lowe report that the company behind ... responsible for the injuries that a woman sustained after ... stress urinary incontinence (SUI). , Carey Danis & Lowe ... litigation and personal injury law. The St. Louis law ...
(Date:9/15/2014)... iFitDress.com, one of the most distinguished dress companies, has ... dresses to its online store. In addition, the company ... They are now provided at very low prices, up to ... confidence in the newly unveiled sapphire evening outfits. “I believe ... all over the world. Up to now, over 200 items ...
(Date:9/15/2014)... 2014 Imaging can be a cost-effective ... might benefit from aggressive intervention, according to a new ... , The study looked at people with asymptomatic carotid ... supplying blood to the head due to atherosclerosis, or ... of up to 20 percent of ischemic strokes, which ...
(Date:9/15/2014)... September 15, 2014 Ticket Down ... tickets for her 2015 Honeymoon Tour. Ariana Grande ... of Boca Raton, Florida has been active in the music ... album, which reached the top of the charts in the ... Association of America for selling more than 400,000 copies. Less ...
Breaking Medicine News(10 mins):Health News:David Bell Joins Triad Semiconductor's Board of Directors 2Health News:Carey Danis & Lowe Reports On $73 Million Boston Scientific Verdict 2Health News:Beautiful Sapphire Evening Dresses Provided By iFitDress.com 2Health News:RSNA: Imaging Identifies Asymptomatic People at Risk for Stroke 2Health News:RSNA: Imaging Identifies Asymptomatic People at Risk for Stroke 3Health News:Ariana Grande Tickets in Fairfax, Uncasville, Philadelphia, Orlando, San Jose, Miami, New York, Detroit, Saint Paul, Chicago, San Antonio, Pittsburgh, Atlanta & Dallas 2Health News:Ariana Grande Tickets in Fairfax, Uncasville, Philadelphia, Orlando, San Jose, Miami, New York, Detroit, Saint Paul, Chicago, San Antonio, Pittsburgh, Atlanta & Dallas 3
... ... , ... May 6, 2010 -- CosmoCom the global leader in Contact Center Consolidation 2.0, ... 2010 Long Island Software Award (LISA). Presented by the Long Island Software and Technology ...
... ... are many Americans struggling to find steady employment in a highly competitive market. In order ... to provide a more youthful, refreshed appearance. Non-surgical med spa treatments can offer many benefits ... ...
... ... are interested in achieving top performance from GPUs in diverse applications using Monte Carlo ... the Numerical Algorithms Group (NAG). , ... (Vocus) May 6, 2010 -- Developers and researchers who are interested ...
... In ... leading online fresh-from-the-farm food and grocery delivery service, is celebrating Nurse Appreciation Week (May ... to nurses at five community hospitals in Westchester and Greenwich, CT. , ... Long Island City, NY ...
... ... its corporate headquarters to King Farm in Rockville, Maryland. The move comes at a time ... ... comprehensive HR solutions, recently announced plans to move its corporate headquarters to King Farm in ...
... There,s no safe amount of alcohol for women during this ... Pregnant woman may have another reason to avoid drinking, with ... the risk for a rare blood cancer in children. , ... acute myeloid leukemia (AML), an often fatal blood cancer, increased ...
Cached Medicine News:Health News:CosmoCom Wins Software Award for CosmoHealth 2Health News:CosmoCom Wins Software Award for CosmoHealth 3Health News:Med Spa Treatments Become More Popular as Unemployment Rates Climb 2Health News:Med Spa Treatments Become More Popular as Unemployment Rates Climb 3Health News:More GPU Routines for Technical Research Now Available from Numerical Algorithms Group 2Health News:More GPU Routines for Technical Research Now Available from Numerical Algorithms Group 3Health News:FreshDirect Celebrates Nurse Appreciation Week with Delivery of Complimentary 4-Minute Meals for Nurses at Hospitals in Westchester and Greenwich, CT 2Health News:FreshDirect Celebrates Nurse Appreciation Week with Delivery of Complimentary 4-Minute Meals for Nurses at Hospitals in Westchester and Greenwich, CT 3Health News:Astra HR Moves its Corporate Headquarters to King Farm, Rockville, MD 2Health News:Astra HR Moves its Corporate Headquarters to King Farm, Rockville, MD 3Health News:Drinking While Pregnant Tied to Rare Leukemia in Offspring 2Health News:Drinking While Pregnant Tied to Rare Leukemia in Offspring 3
... Diagnostics is a leading provider of immunofluorescence ... test menu that includes kits for autoimmune ... as miscellaneous conjugates and components. Our Impact ... assortment of substrates and kit sizes to ...
... disease ELISA products make us a leader ... for faster integration into the busy laboratory, ... reliability and run-to-run consistency. Our Infectious Disease ... a wide range of serological assays including ...
... of infectious disease ELISA products make us ... assay protocols for faster integration into the ... provide increased reliability and run-to-run consistency. Our ... assays for a wide range of serological ...
... infectious disease ELISA products make us a ... protocols for faster integration into the busy ... increased reliability and run-to-run consistency. Our Infectious ... for a wide range of serological assays ...
Medicine Products: