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Human Genome Sciences Announces Fourth-Quarter and Full-Year 2008 Financial Results and Key Developments

and costs associated with facilities, intense competition, the uncertainty of patent and intellectual property protection, the Company's dependence on key management and key suppliers, the uncertainty of regulation of products, the impact of future alliances or transactions and other risks described in the Company's filings with the Securities and Exchange Commission. In addition, while the Company has begun shipment of ABthrax to the U.S. Strategic National Stockpile, the Company will continue to face risks related to acceptance of future shipments and FDA's approval of the Company's Biologics License Application for ABthrax, if and when it is submitted. If the Company is unable to meet requirements associated with the ABthrax contract, future revenues from the sale of ABthrax to the U.S. Government will not occur. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of today's date. Human Genome Sciences undertakes no obligation to update or revise the information contained in this announcement whether as a result of new information, future events or circumstances or otherwise.


                            Three months ended         Twelve months ended
                               December 31,                December 31,
                            2008            2007       2008        2007
                            ----            ----       ----        ----
                    (dollars in thousands, except share and per share amounts)

    Revenue - R&D contracts    $12,906      $12,526      $48,422      $41,851

    Costs and expenses:
      Research and
       development(a)           48,516       87,312      242,710      245,745
      General and
       administrative(b)        14,860       16,125       60,865       55,874
      Lease terminati
SOURCE Human Genome Sciences, Inc.
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