Navigation Links
How IT Helps Solve Pharma's R&D Problems: in silico Drug Discovery
Date:11/8/2010

ore predictive to increase the number of drug successes 15

The use of virtual models is rare during target identification and validation 16

The greatest bottlenecks reside in lead generation and optimization 16

Poor ADMET is the cause of majority of drug failures in late-stage development 17

Systems biology and the 'omics' add another layer to in silico technologies 18

TECHNOLOGY FOCUS: IN SILICO TECHNOLOGIES MUST ENHANCE DRUG DISCOVERY 19

Drug discovery requires high performance computing 19

Cloud computing is facilitating the use of predictive modeling and molecular simulations 19

Amazon is the current mainstream cloud provider for the life sciences industry 20

Pre-built versus custom models - different needs for different companies 20

Companies are debating between building their own models or seeking external services 21

Data management is the backbone of in silico research 21

In silico technologies must offer benefits across the R&D spectrum 21

Target identification and validation are not high on the priority list for in silico model development 22

Computer simulations and modeling must complement high throughput screening 22

In silico needs to provide predictive ADMET earlier in the discovery and development process 22

In silico must go beyond traditional drug discovery 22

The complexity of drug discovery has resulted in a diverse vendor market 23

RECOMMENDATIONS 25

Recommendations for pharma and biotech companies 25

With R&D productivity hitting rock bottom, research must incorporate in silico methods 25

Scientists must test the waters before making a final decision on in silico technologies 25

Collaboration with the larger research community and technology vendors is a necessity for growth 26

Recommendations for vendors 26

Vendors must engage with customers as if they too were part of
'/>"/>

SOURCE Reportlinker
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. VelaShape™ Helps Moms Regain their Body Confidence after Baby
2. Cranewares Pharmacy ChargeLink® Version 3 Helps Improve Margins and Control Costs
3. Innovative Web-based Tool Helps Doctors Improve Care
4. Cardinal Health Helps Health Care Providers Prepare for 2010-2011 Flu Season
5. Newly Re-launched Website Helps PhDs and MDs Capitalize on Growth in Life Science Industries
6. Results of Pilot Study Published in Journal Music and Medicine Reveal The Listening Program Helps Children With Down Syndrome Improve Speech Skills
7. Innovative Partnership Helps Improve Medical Research by Optimizing Clinical Trials
8. New White Paper Helps Medical Device Manufacturers Apply New FDA Regs to Combination Products
9. Power Wheelchair From Medicare Helps Save Elderly Alabama Woman From Raging Fire That Destroyed Her Home of 40 Years
10. Exclusive Mapping Tool Helps Create Walking Communities
11. New White Paper Helps Medical Device Manufacturers Validate Cleaning Processes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... 17, 2014 BRIC Biopsy Devices Market Outlook ... new report, "BRIC Biopsy Devices Market Outlook to 2020", ... market. The report provides value, in millions of US ... dollars) within market segments - Biopsy Guns (Disposable and ... Needles (Disposable and Reusable Fine Aspiration Needles) and Disposable ...
(Date:9/17/2014)... Brazil Gynecological Devices Market ... GlobalData,s new report, "Brazil Gynecological Devices Market ... the Brazil Gynecological Devices market. The report provides ... units) and average prices (in US dollars) within ... Devices (Micro-inserts) and Mechanical Sterilization Devices (Tubal Clips ...
(Date:9/17/2014)... Sept. 17, 2014 The ambulance ... last decade due to the recession, an ... technological advancements. This BCC Research report analyzes ... of the ambulance and emergency medical services ... and hemorrhage control devices, equipment used for ...
Breaking Medicine Technology:BRIC Biopsy Devices Market Outlook to 2020 2BRIC Biopsy Devices Market Outlook to 2020 3Brazil Gynecological Devices Market Outlook to 2020 2Brazil Gynecological Devices Market Outlook to 2020 3Ambulance and Emergency Equipment: Global Markets 2Ambulance and Emergency Equipment: Global Markets 3Ambulance and Emergency Equipment: Global Markets 4
... Bulletin Board: HEWA ), a leading retail ... clinic system offering medical services in the Spokane, Washington ... 30-day supply of more than 300 generic prescription medications ... Medical Associate,s "Columbia Care" program offers preventive primary healthcare ...
... Cogdell Spencer ERDMAN President and CEO, Frank Spencer turned ... organizations in the Charlotte community. Frank Spencer ... as President and Chief Executive Officer of Cogdell Spencer ... three local housing ministries with which he has worked ...
Cached Medicine Technology:HealthWarehouse.com Partners with Columbia Medical Associates to Bring Affordable Healthcare to Washington State 2Retirement Event Turned Fundraiser Brings in More Than $35,000 for Local Housing Ministries 2
(Date:9/18/2014)... 18, 2014 CD-adapco, the largest privately ... today announced its new partnership with Ben Ainslie Racing. ... simulation tool, STAR-CCM+® in the design of its racing ... in the 35th America’s Cup taking place in 2017. ... America’s Cup is sustainability, the set of restrictive rules ...
(Date:9/18/2014)... in Spain of newborns with a gestational age under 26 ... ,exceptional, although other factors such as birth weight and sex ... of Neonatology have studied the survival rates in Spain of ... account that a newborn carried to term is between 37 ... the national database that gathers information on all babies born ...
(Date:9/18/2014)... Coral Gables, FL (PRWEB) September 18, 2014 ... donate a portion of proceeds to Feeding America Eastern ... “7 Days, 7 Ways to Save” with Turbana bananas ... will be two for $4 and Turbana bananas will ... donate $1 for every two Fyffes pineapples that are ...
(Date:9/18/2014)... Dotinga HealthDay Reporter WEDNESDAY, ... largest number of post-traumatic stress disorder symptoms are almost three ... new study suggests. The findings don,t prove a ... to food. And it,s also possible that certain women are ... Still, the research seems to add to existing ...
(Date:9/18/2014)... September 18, 2014 How much is ... one of the factors contributing to the obesity epidemic ... a single serving and how to manage portion size ... presentation Oct. 3 at Humility House, 755 Ohltown Road, ... will lead the informational discussion and answer questions from ...
Breaking Medicine News(10 mins):Health News:Ben Ainslie Racing Using STAR-CCM+ Simulation Software to Design 35th America’s Cup Racing Boat 2Health News:The viability of premature babies is minimal at 22 weeks' gestation 2Health News:Turbana Partners with Sendik's Food Market to Donate Portion of Proceeds to Local Hunger-Relief Non-Profit 2Health News:Turbana Partners with Sendik's Food Market to Donate Portion of Proceeds to Local Hunger-Relief Non-Profit 3Health News:PTSD Link to Food Addiction Seen in Report 2Health News:PTSD Link to Food Addiction Seen in Report 3Health News:HMHP Workshop Addresses Portion Control 2
... ... Practices of Mind Control Cult. Inspired by numerous responses to his first ... AMORC Unmasked! This book goes into greater depth, exposing the hidden mind ... called AMORC, but also defending the possibility for a true spiritual path ...
... 13 /PRNewswire-FirstCall/ - The Westaim Corporation announced today that for the ... $0.2 million, or zero cents per share, on revenues of $6.7 ... cents per share, on revenues of $5.5 million in the same ... for the quarter ended September 30, 2009 was $0.02 million compared ...
... , HOUSTON, Nov. 13 Plagued by a growing weakness that ... 11-year-old Iraqi Aram Ali was a shell of the bright little girl ... wrong. Not the 13 doctors her distraught parents saw in Syria, not ... physicians she had seen in Iraq, the war-torn country the family had ...
... Million Project Expected to Create 1,500 Jobs , HERSHEY, Pa., ... start of construction on the new Penn State Hershey Children,s ... for the regional economy, but most importantly, for sick children ... 300 construction jobs and another 1,200 jobs once the facility ...
... , NEW HAVEN, Conn., Nov. 13 On November 12th ... celebrated the ribbon cutting ceremony for its New Haven dental ... During the celebration, Kool Smiles dentists were joined by state ... health in New Haven and Kool Smiles, commitment to providing ...
... Today, Lung Cancer Alliance (LCA) formally thanked New Mexico ... Month throughout his state. , (Logo: http://www.newscom.com/cgi-bin/prnh/20081016/LCALOGO ... praised the New Mexico Governor and the Legislature for leadership ... for lung cancer. , "New Mexico is taking the issue ...
Cached Medicine News:Health News:Pierre S. Freeman Adds Book AMORC Unmasked! To his Arsenal of Whistleblower Weapons Aimed at Rosicrucian Order 2Health News:Pierre S. Freeman Adds Book AMORC Unmasked! To his Arsenal of Whistleblower Weapons Aimed at Rosicrucian Order 3Health News:Westaim announces 2009 third quarter results 2Health News:Westaim announces 2009 third quarter results 3Health News:Westaim announces 2009 third quarter results 4Health News:Physicians Heal Bridge to Nowhere; Iraqi Girl With Rare Neuromuscular Disorder Has New Hope 2Health News:Physicians Heal Bridge to Nowhere; Iraqi Girl With Rare Neuromuscular Disorder Has New Hope 3Health News:Physicians Heal Bridge to Nowhere; Iraqi Girl With Rare Neuromuscular Disorder Has New Hope 4Health News:Physicians Heal Bridge to Nowhere; Iraqi Girl With Rare Neuromuscular Disorder Has New Hope 5Health News:Governor Rendell Helps to Break Ground for New Children's Hospital at Penn State Hershey 2Health News:Mayor John DeStefano Declares November 12th Kool Smiles Day 2Health News:Lung Cancer Alliance Hails New Mexico Proclamation on Lung Cancer Awareness Month 2
Direct assays, no sample extraction, hydrolysis or other pretreatment required. Highly specific antiserum, minimal cross-reactivity with estrone, estradiol and other estrogen metabolites....
Helmer's Horizon Series line of refrigerators are designed specifically for the cost conscious buyer. This line offers outstanding performance, quality, and the features you need to ensure the safety...
... Helmer presents the ... with innovative solutions for ... more sophisticated features than ... Bank Refrigerators are at ...
... the precise requirements of blood banking ... Bank Equipment meets American Association of ... Cross (ANRC) and U.S. Food & ... freezers, and platelet incubators feature alarm ...
Medicine Products: