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Hospira Japan Receives Approval for New Indication for 'Precedex IV™ 200ug'
Date:8/22/2010

tients spent within the targeted sedation range. The results also demonstrated safety of Precedex when used long-term in terms of frequency of side effects and combined administration with other sedatives/ analgesics.

Precedex is a central alpha-2 receptor agonist and it is the first drug in its class approved as a sedative in the intensive care setting. It has been shown to be an effective agent for mild to moderate sedation in the intensive care setting and it reduces the need for opioids without compromising patient comfort. The product is sold in more than 30 markets around the world.

The expanded indication offers an additional option for sedation management in the intensive care setting and more possibilities for sedation/pain management.

"I think it is extremely significant that greater-than-24-hour administration of Precedex in an intensive care unit has become possible, which is a new indication much awaited by healthcare providers," said Makoto Ozaki, M.D., Ph.D., Professor and Chairman of Department of Anesthesiology at Tokyo Women's Medical University, who led the long-term administration study as the principal investigator. "We were often forced to use other sedatives because of the restraint that did not allow us to administer Precedex for more than 24 hours and manage the sedation using the sedative's excellent features, which was really unfortunate. The new indication will allow us to avoid such a situation, and represents significant progress that will be greatly appreciated by patients."

Hospira is continuing its efforts to bring this important medication to new markets. Prior to the approval of long-term use of Precedex in Japan, the product was launched in Canada and South Korea earlier this year.

For Clinicians

Precedex IV ™200ug

Precedex IV™200ug (generic name: dexmedetomidine hydrochloride) is a highly selective central alpha-2 adrenoceptor agonist sedative that
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SOURCE Hospira, Inc.
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